Copyright
©2008 The WJG Press and Baishideng.
World J Gastroenterol. Jul 28, 2008; 14(28): 4535-4539
Published online Jul 28, 2008. doi: 10.3748/wjg.14.4535
Published online Jul 28, 2008. doi: 10.3748/wjg.14.4535
Table 2 Incidence and risk of side effects in two groups
| Celecoxib, n (%) | Placebo, n (%) | OR (95% CI) | |
| Gastroduodenal ulcer | 19 (3.72) | 17 (3.31) | 1.13 (0.58-2.22) |
| CV events | 4 (0.86) | 5 (1.06) | 0.84 (0.23-3.15) |
| Main nonadjudicated side effects | |||
| Abdominal pain | 8 (1.73) | 13 (2.75) | 0.62 (0.26-1.52) |
| Bloating | 19 (4.10) | 7 (1.48) | 2.85 (1.19-6.84) |
| Constipation | 9 (1.94) | 15 (3.17) | 0.61 (0.26-1.40) |
| Diarrhea | 24 (5.18) | 24 (5.07) | 1.02 (0.57-1.83) |
| Dizziness | 25 (5.40) | 36 (7.61) | 0.69 (0.41-1.17) |
| Gastric spasmus | 15 (3.24) | 15 (3.17) | 1.02 (0.49-2.12) |
| Headache | 26 (5.62) | 23 (4.86) | 1.16 (0.65-2.07) |
| Heartburn | 29 (6.26) | 23 (4.86) | 1.31 (0.75-2.30) |
| Loss of appetite | 25 (5.40) | 16 (3.38) | 1.63 (0.86-3.10) |
| Muscle pain | 55 (11.88) | 70 (14.80) | 0.78 (0.53-1.13) |
| Nausea | 14 (3.02) | 17 (3.59) | 0.84 (0.41-1.72) |
| Pain in the chest | 16 (3.46) | 17 (3.59) | 0.96 (0.48-1.92) |
| Palpitations | 22 (4.75) | 16 (3.38) | 1.43 (0.74-2.75) |
- Citation: Feng GS, Ma JL, Wong BC, Zhang L, Liu WD, Pan KF, Shen L, Zhang XD, Li J, Xia HH, Li JY, Lam SK, You WC. Celecoxib-related gastroduodenal ulcer and cardiovascular events in a randomized trial for gastric cancer prevention. World J Gastroenterol 2008; 14(28): 4535-4539
- URL: https://www.wjgnet.com/1007-9327/full/v14/i28/4535.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.4535