Topic Highlight
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Jul 7, 2008; 14(25): 3974-3981
Published online Jul 7, 2008. doi: 10.3748/wjg.14.3974
Table 1 Mayo criteria for the diagnosis of PSC[27]
Mayo criteria
Typical cholangiographic abnormalities involving any part of the biliary treeMultifocal stricturing and beading, usually involving both the intrahepatic and extrahepatic biliary system
Compatible clinical and biochemical findings (for longer than 6 mo)Cholestatic symptoms, history of inflammatory bowel disease
Twofold to threefold increase in serum alkaline phosphatase levels
Exclusion of identifiable causes of secondary sclerosing cholangitisAIDS cholangiopathy
Bile duct neoplasm (unless diagnosis of PSC previously established)
Biliary tract surgery, trauma
Choledocholithiasis
Congenital abnormalities of biliary tract
Caustic sclerosing cholangitis
Ischemic stricturing of bile ducts
Toxicity or stricturing of bile ducts related to intra-arterial infusion of floxuridine