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Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. May 7, 2008; 14(17): 2650-2661
Published online May 7, 2008. doi: 10.3748/wjg.14.2650
Table 6 Relief of abdominal pain in 11 probiotic/placebo treatment arms
ReferenceProbioticImprovement in abdominal pain
Definition of secondary outcome1
Probiotic n/n (%)Placebo n/n (%)
Gade[46]Strept faecalis25/32 (78)10/22 (45)Absence or presence of symptom
Nobaek[48]L. plantarum9/25 (36)5/27 (18)Decrease ≥ 1.5 on VAS symptom scale
O'Sullivan[49]L. rhamnosus GG9/19 (47)12/19 (63)Symptom improved
Niedzielin[50]Lacto plantarum20/20 (100)11/20 (55)Absence of symptoms
Bausserman[52]Lacto rhamnosus GG11/25 (44)10/25 (40)Decrease of ≥ 1 point symptom score
Kajander[54]L. rhamnosus GG + L. rham. LC705 + Bifid. breve Bb99 +Prop. freudenreichii27/41 (66)17/40 (43)Symptoms alleviated
Whorwell[35]Bifido. infantis (106 dose)32/74 (43)39/76 (52)Adequate relief of symptoms
Whorwell[35]Bifido. infantis (108 dose)42/72 (59)39/76 (52)Adequate relief of symptoms
Whorwell[35]Bifido. infantis (1010 dose)28/71 (39)39/76 (52)Adequate relief of symptoms
Enck[59]E. coli + Strept faecalis108/149 (72)66/148 (45)≥ 50% decrease in symptom score
Gawronska[60]Lacto rhamnosus GG6/18 (33)1/19 (5)Absence of pain