Vascular endothelial growth factor attenuates hepatic sinusoidal capillarization in thioacetamide-induced cirrhotic rats

Figure 5 TEM. A: Normal state, LSECs and fenestrae (arrowhead). Bar denotes 200 nm; B: Normal state. Cell conjuction between LECs (small arrowhead) and microvilli of hepatocytes (large arrowhead). Bar denotes 100 nm; C: Cirrhotic state. Fenestrae, cell conjuction and microvilli of hepatocytes disappeared, and a basement membrane appeared (arrowhead). Bar denotes 500 nm; D: VEGF treated group. Fenestrae (small arrowhead), microvilli (large arrowhead) and cell conjunctions between LECs (triangle) appeared, Bar denotes 200 nm.