Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection: A study from northern India

Table 4 H pylori infection and COX-2 polymorphism as risk for peptic ulcer disease

H pylori status	COX-2 genotype	Peptic ulcer disease (n = 45)	Non-ulcer dyspepsia (Controls, n = 241)	OR (95% CI)	P-value
HP-	GG	8	79	Referent
HP-	C carriers	1	29	0.86 (0.09-7.48)	0.89
HP+	GG	23	92	2.83 (1.18-6.73)	0.019
HP+	C carriers	13	41	5.65 (2.07-15.34)	< 0.001

HP-: H pylori negative; HP+: H pylori positive.