Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture

Table 1 Test sensitivity of delisheng in 3d and 2d cell culture

Concentration (μL/mL)	Inhibition ratio (%)
	3-d	Monolayer	P value
12.5	11.73 ± 11.58	33.81 ± 10.54	0.014
25	20.94 ± 8.29	37.79 ± 9.55	0.018
50	25.45 ± 5.62	46.01 ± 6.32	0.001
100	36.69 ± 5.37	75.65 ± 10.47	< 0.001
200	43.93 ± 7.81	84.62 ± 3.24	< 0.001