Hyperplastic polyposis associated with two asynchronous colon cancers

Figure 2 A: Tubular adenoma located in the transverse colon (HE, × 100). The lesion shows duct proliferation and cells that have mild nuclear atypia; B: Hyperplastic polyp located in the transverse colon (HE, × 200). Serrated ducts with no atypical features are observed; C: Hyperplastic polyp located in the ascending colon (HE, × 100). Serrated ducts with no atypical features are observed. The inflammatory infiltration is mainly composed of lymphocytes in the lamina propria; D: High-grade serrated adenoma located in the sigmoid colon (HE, × 200). Papillary or serrated structures with obvious atypical cells are seen. Atypical structures, such as fusion of the tubular structure, are also shown. There is no evidence of malignancy.