Advances in small animal mesentery models for in vivo flow cytometry, dynamic microscopy, and drug screening

Figure 10 High-resolution monitoring of cell behavior in lymph flow. Top row (A-C): three sequential images of an individual RBC’s rotation in lymph flow (lymphatic diameter 185 μm, mean cell velocity 220 μm/s, magnification 100 ×). Bottom row: moving aggregates of different sizes in lymph flow; D: Unstable aggregate of a few cells in intact lymphatic; E: large aggregate of RBCs in lymph flow resulting from venous insufficiency; F: rouleaux formation when numerous RBCs appeared in lymph flow due to laser-induced hemorrhage (magnification 100 ×).