Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials

Table 4 Descriptors for group R1 of all fluoroquinolones compounds

No.	R1
	SA1	V1	HE1	LP1	RF1	P1	MW1
1	162.65	191.65	-4.39	-0.41	6.5	3.64	30.05
2	184.12	230.99	2.6	1.13	10.1	5.41	41.07
3	183.13	229.07	2.59	1.13	10.1	5.41	41.07
4	181.83	225.71	2.61	1.13	10.1	5.41	41.07
5	232.61	320.17	-3.57	1.43	24.71	9.18	96.08
6	171.57	206.82	0.73	1.32	7.29	4.35	29.06
7	192.14	241.82	2.56	1.13	10.1	5.41	41.07
8	180.91	225.56	2.61	1.13	10.1	5.41	41.07
9	185.87	233.6	2.57	1.13	10.1	5.41	41.07
10	209.76	274.58	0.58	2.4	13.05	6.37	58.08
11	173.79	211.56	0.71	1.32	7.29	4.35	29.06
12	172.99	213.28	0.7	1.32	7.29	4.35	29.06
13	213.93	278.93	0.71	2.4	13.05	6.37	58.08
14	172.31	210.04	0.72	1.32	7.29	4.35	29.06
15	187.74	241.74	-1.24	0.8	15.93	7.69	60.11
16	194.84	249.45	2.6	0.82	9.92	5.32	59.06
17	193.09	243.16	2.55	1.13	10.1	5.41	41.07
18	246.11	343.09	-3.4	2.14	26.43	9.8	113.09
19	246.34	343.09	-3.4	2.14	26.43	9.8	113.09
20	239.88	334.78	-2.47	2	26.21	9.89	95.1
21	168.2	205.76	0.8	0.92	7.37	4.26	47.05
22	248.12	343.14	-3.4	2.14	26.43	9.8	113.09