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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 21, 2007; 13(11): 1715-1722
Published online Mar 21, 2007. doi: 10.3748/wjg.v13.i11.1715
Published online Mar 21, 2007. doi: 10.3748/wjg.v13.i11.1715
Table 3 Comparison between patients with both Hashimoto’s thyroiditis and coeliac disease compared to patients with coeliac disease only
| Characteristics | Patients with only | Patients with both coeliac disease | P |
| coeliac disease | and Hashimoto’s thyroirditis | ||
| n = 140 | n = 27 | ||
| Positive any or combinations of coeliac serology, n (%) | 60 (43) | 16 (59) | < 0.05 |
| IgA anti-gliadin | 43 (31) | 12 (44) | < 0.05 |
| IgG anti-gliadin | 41 (29) | 16 (59) | < 0.01 |
| IgA anti-tissue transglutaminase | 43 (31) | 14 (50) | < 0.01 |
| IgA anti-endomysium | 46 (33) | 14 (52) | < 0.01 |
| Positive for HLA-DQ 2 and/or 8, n (%) | |||
| DQ2 heterozygote | 83 (59) | 20 (74) | < 0.05 |
| DQ2 homozygote | 38 (27) | 3 (11) | < 0.01 |
| DQ8 heterozygote | 9 (6) | - | - |
| DQ8 homozygote | 3 (2) | - | - |
| Combined DQ2 & DQ8 | 7 (5) | 4 (15) | < 0.05 |
| Small bowel histology, n (%) | |||
| Marsh 0 | 13 (9) | - | - |
| Marsh I | 13 (9) | 2 (7) | > 0.05 |
| Marsh II | 6 (4) | 2 (7) | > 0.05 |
| Marsh IIIa | 49 (35) | 12 (44) | > 0.05 |
| Marsh IIIb | 42 (30) | 6 (22) | > 0.05 |
| Marsh IIIc | 17 (12) | 5 (19) | > 0.05 |
| Villous atrophy | 108 (77) | 23 (85) | > 0.05 |
| Presence of autoimmune diseases, n (%) | 5 (4) | 7 (26) | < 0.01 |
- Citation: Hadithi M, de Boer H, Meijer JW, Willekens F, Kerckhaert JA, Heijmans R, Peña AS, Stehouwer CD, Mulder CJ. Coeliac disease in Dutch patients with Hashimoto’s thyroiditis and vice versa. World J Gastroenterol 2007; 13(11): 1715-1722
- URL: https://www.wjgnet.com/1007-9327/full/v13/i11/1715.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i11.1715