Viral and cellular determinants involved in hepadnaviral entry

Figure 1 Schematic presentation of human (HBV) and duck (DHBV) hepatitis B virus. The viral DNA is drawn as a single or double line. The viral polymerase is depicted with the primer domain (pr) and the reverse transcription domain (RT). The nucleocapsid (core or HBc/DHBc) is shown in black. Reported encapsidated cellular proteins are omitted. For HBV the surface proteins L, M and S are shown with the S-domain, the preS2-domain and the preS1-domain, whereas for DHBV, L- and S-surface proteins with preS and S-domain are depicted. St, truncated form of DHBV S-surface protein. Non-infectious subviral particles of HBV are shown in filamentous and spherical form and in larger spheroids in the case of DHBV.