Neutrophil depletion-but not prevention of Kupffer cell activation-decreases the severity of cerulein-induced acute pancreatitis

Table 2 Pulmonary injury in control (CONT) mice and mice treated with cerulein (CER)

	CONT	CER
Pancreatic water content (% wet weight) 0.74 [0.71 – 0.76] 0.80 [0.78 - 0.83] P < 0.0001 Pancreatic MPO activity (U/mg tissue dry weight) 322 [125 - 456] 2738 [1978 - 3245] P = 0.0002 Pancreatic necrosis (%) 1.26 [0.5 – 2.3] 27.7 [24.5 – 35.0] P = 0.0001 CONT CER Pulmonary MPO activity (U/mg tissue dry weight) 947 [782 - 1145] 10173 [8710 - 12035] P < 0.0001 Pulmonary permeability index 0.57 [0.5 – 0.8] 3.9 [3.1 - 5.1] P = 0.0002 Pulmonary MPO activity (U/mg tissue dry weight)	947 [782 - 1145]	10173 [8710 - 12035]	P < 0.0001
Pulmonary permeability index	0.57 [0.5 – 0.8]	3.9 [3.1 - 5.1]	P = 0.0002

MPO = myeloperoxidase. Pulmonary permeability index: ratio of FITC-labeled bovine albumin between bronchoalveolar lavage and serum. n ≥ 5 in each group. Pulmonary MPO activity and pulmonary permeability index were compared by Mann-Whitney test.