Management of digestive bleeding related to portal hypertension in cirrhotic patients: A French multicenter cross-sectional practice survey

Table 3 Management of the bleeding event in 126 consecutive patients: conformity with the Baveno III consensus and regional variability

Baveno III guidelines	n (%) of cases complying with the guidelines(95% confidence limits)	Variability among sectors(range, P a)
Endoscopy within 12 h after admission from home	60 (60%) (50%-70%)	52% to 71% P = 0.85
Blood restitution to maintain hematocrit at 25% to 30%	84 (89%) (81%-95%)	ND
	(n = 94 patients transfused)
Early vasoactive drug infusion	110 (87%) (80%-92%)	71% to 100% P = 0.081
	Median time after admission: 2 h
Endoscopic treatment: ligation or sclerosis	- Ligation 52 (42%) (33%-51%)	29% to 61% P = 0.17
	- Sclerosis 26 (21%) (14%-29%)	7% to 43% P = 0.29
Antibiotic prophylaxis	81 (64%) (55%-73%)	50% to 75% P = 0.41
	Prophylaxis 87%/infection 13%
Lactulose administration	50 (40%) (32%-49%)	26% to 86% P = 0.041
	Prophylaxis 57%/encephalopathy 43%
Prophylaxis of rebleeding: beta blockers or ligation	- Beta-blockers alone 31% (22%-41%)	0 to 45%
	- Ligation and beta-blockers 33%	16% to 100%
	(24%-43%)
	- Ligation alone 19% (12%-29%)	0 to 37%
	- Others or none 17% (10%-26%)	0 to 44%
		P = 0.0003

ND: variability not assessed.

^aGeneralized Fisher’s exact test of the homogeneity in practices among the six geographic sectors (five regions and two combined counties).