Induction of apoptosis on human hepatocarcinoma cell lines by an alkyl resorcinol isolated from Lithraea molleoides

Figure 2 Treatment with 5-AR induces morphological changes typical of apoptosis in HepG2 and Hep3B cells. Control or treated cells were observed under contrast phase microscopy and photographed. A: Control untreated HepG2 cells (100 x magnification); B: HepG2 cells treated for 24 h with 5-AR IC50 (100 x magnification); C: HepG2 cells treated for 24 h with 5-AR IC50 (200 x magnification); D: control untreated Hep3B cells (100 x magnification); E: Hep3B cells treated for 24 h with 5-AR IC50 (100 x magnification); F: Hep3B cells treated for 24 h with 5-AR IC50 (200 x magnification). Results are from one experiment that is representative of three similar ones.