Comparative clinical trial of S-pantoprazole versus racemic pantoprazole in the treatment of gastro-esophageal reflux disease

Table 3 Between-group efficacy in improvement of symptoms

Decrease compared to baseline (d 0) in score	Patients showing improvement in symptoms (n)
	Heart burn				Regurgitation				Bloating
	On d 14		On d 28		On d 14		On d 28		On d 14		On d 28
	Ref	Test	Ref	Test	Ref	Test	Ref	Test	Ref	Test	Ref	Test
Decrease by 1	89	93	56	71	90	111	76	86	62	81	69	65
Decrease by 2	9	21	61	67	6	12	52	52	11	14	36	38
Decrease by 3	0	1	11	15	0	2	8	20	3	2	9	21
Patients who improved (n)	98	115	128	153	96	125	136	158	76	97	114	124
Patients with symptoms (n)	172	179	172	179	165	170	165	170	149	143	149	143
Fisher’s test, P	0.19		0.01		0.004		0.004		0.004		0.03