Liver fibrosis and tissue architectural change measurement using fractal-rectified metrics and Hurst’s exponent

Figure 4 Comparative analysis of Markovian sequence of the amount of fibrosis, and the three sequences expressing the classes of magnitude of the collagen islets identified in 209 needle biopsy specimens. (1). Markovian sequence of the total amount of fibrosis in a histological biopsy section (blue line); (2). Percentage of collagen islets with a magnitude of 10⁴-10⁶μm² (red line); (3). Percentage of collagen islets with a magnitude of 10³-10⁴μm² (fuchsia line); (4). Percentage of collagen islets with a magnitude of 10¹-10³μm² (green line).