Liver fibrosis and tissue architectural change measurement using fractal-rectified metrics and Hurst’s exponent

Table 1 Intra-sample variability in the area and wrinkledness of fibrosis

Patient number	n	ACF(%)	CV	W	CV	H	CV
1	30	5.97 ± 4.95	0.83	788.63 ± 590.48	0.75	0.51 ± 0.14	0.27
2	30	9.77 ± 2.64	0.27	830.52 ± 124.93	0.15	0.475 ± 0.04	0.08
3	30	20.15 ± 5.51	0.27	69 ± 140.88	0.18	0.38 ± 0.03	0.09

Note: Patient No.1 = Without pathology; Patient No.2 = Chronic hepatitis with intial fibrosis; Patient No.3 = Cirrhosis; n = number of sequential sections; A_CF = Fractal fibrosis area; CV = Coefficient of variability (standard deviation/mean); H = Hurst' exponent.