Initial experience from a combination of systemic and regional chemotherapy in the treatment of patients with nonresectable cholangiocellular carcinoma in the liver

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Feb 28, 2005 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Feb 28, 2005; 11(8): 1091-1095
Published online Feb 28, 2005. doi: 10.3748/wjg.v11.i8.1091

Table 2 Present status, chemotherapy-related response and changes of tumor markers.

Patient number	Observervation period (mo)	Maximum response	Highest tumor markers before	Lowest tumor marker under therapy (%)	Time to tumor progression (mo)	Survival therapy (mo)
1	10	SD	None	-	7	Dead (10)
2	14	SD	Ca15-3:48	47 (-2¹)	5	Alive
3	18	PR	Ca19-9:1 442	34 (-98¹)	18	Alive
4	12	PR	Ca19-9:89	19 (-77¹)	NA (still PR)	Alive
			AFP:35	6 (-83¹)
5	10	PR	Ca19-9:786	139 (-82¹)	NA resected after 10	Alive
6	16	SD	Ca15-3:54	43 (-20¹)	7	Alive
			Ca19-9:88	115 (+31¹)
7	12	SD	Ca19-9:845 200	435 (-99¹)	7
			CEA:285	2 (-99¹)		Alive
8	9	SD	Ca15-3:435	204 (-53¹)	3
			Ca19-9:117	84 (-28¹)		Dead (9)

¹Change of tumor marker in percent compared to highest value before therapy NA: not assessable.

Citation: Kirchhoff T, Zender L, Merkesdal S, Frericks B, Malek N, Bleck J, Kubicka S, Baus S, Chavan A, Manns MP, Galanski M. Initial experience from a combination of systemic and regional chemotherapy in the treatment of patients with nonresectable cholangiocellular carcinoma in the liver. World J Gastroenterol 2005; 11(8): 1091-1095
URL: https://www.wjgnet.com/1007-9327/full/v11/i8/1091.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i8.1091