Serum insulin, insulin resistance, &beta;-cell dysfunction, and gallstone disease among type 2 diabetics in Chinese population: A community-based study in Kinmen, Taiwan

doi:10.3748/wjg.v11.i45.7159

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Dec 7, 2005 (publication date) through Apr 22, 2024

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Dec 7, 2005; 11(45): 7159-7164
Published online Dec 7, 2005. doi: 10.3748/wjg.v11.i45.7159

Table 1 Crude and age-adjusted odds ratios of baseline-associated factors of GSD among type 2 diabetics in Kinmen

	GSD (yes vs no)
	Male				Female
	Crude OR (95%CI)		Age-adjusted OR (95%CI)		Crude OR (95%CI)		Age-adjusted OR (95%CI)
Age (≥65 vs ＜65 yr)	3.14	(1.32-7.47)^a	-	-	2.25	(1.04-4.90)^a	-	-
Type 2 diabetes (known vs new cases)	0.90	(0.34-2.39)	0.87	(0.32-2.34)	1.44	(0.68-3.02)	1.46	(0.68-3.13)
FPG (≥11.1 vs ＜11.1 mmol/L)	2.12	(0.70-6.37)	1.95	(0.64-5.94)	1.24	(0.50-3.07)	1.49	(0.59-3.79)
SBP (≥140 vs ＜140 mmHg)	1.70	(0.73-3.97)	1.50	(0.63-3.56)	2.59	(1.23-5.46)^a	1.99	(0.92-4.31)
DBP (≥90 vs ＜90 mmHg)	1.44	(0.62-3.35)	1.57	(0.67-3.73)	1.12	(0.52-2.42)	1.21	(0.55-2.67)
Obesity (yes vs no)	2.04	(0.85-4.88)	2.00	(0.83-4.83)	2.97	(1.30-6.83)^a	2.88	(1.24-6.70)^a
Central obesity (yes vs no)	2.76	(1.13-6.77)^a	2.36	(1.01-5.97)	1.85	(0.68-5.02)	1.47	(0.53-4.09)
Cholesterol (≥5.17 vs ＜5.17 mmol/L)	1.02	(0.19-1.91)	0.88	(0.18-1.09)	0.92	(0.45-1.88)	0.85	(0.41-1.77)
Triglyceride (≥2.24 vs ＜2.24 mmol/L)	1.92	(0.12-2.36)	1.61	(0.13-2.84)	1.43	(0.20-2.46)	1.35	(0.15-1.96)
BUN (≥7.14 vs ＜7.14 mmol/L)	0.44	(0.16-1.25)	0.38	(0.13-1.09)	1.65	(0.75-3.61)	1.30	(0.58-2.93)
Uric acid (high vs normal)	0.30	(0.09-1.06)	0.29	(0.08-1.03)	1.61	(0.77-3.38)	1.12	(0.51-2.48)
AST (≥40 vs ＜40 U/L)	1.05	(0.08-5.72)	0.60	(0.07-5.31)	3.68	(1.01-9.32)^a	3.93	(1.04-10.89)^a
ALT (≥40 vs ＜40 U/L)	1.09	(0.19-4.33)	1.09	(0.21-5.61)	2.00	(0.67-6.02)	2.20	(0.71-6.85)
Serum insulin (2^ndvs 1^st quartile)	0.29	(0.06-1.33)	0.30	(0.06-1.39)	1.39	(0.44-4.40)	1.68	(0.52-5.45)
(μU/mL) (3^rdvs 1^st quartile)	0.61	(0.19-2.00)	0.56	(0.17-1.86)	2.05	(0.71-5.88)	2.20	(0.75-6.45)
(4^thvs 1^st quartile)	0.61	(0.18-2.03)	0.65	(0.20-2.17)	5.38	(2.14-13.48)^a	5.32	(2.08-13.64)^a
Log HOMA IR (2^ndvs 1^st quartile)	0.61	(0.19-2.00)	0.60	(0.18-1.99)	1.17	(0.38-3.57)	1.65	(0.52-5.29)
(3^rdvs 1^st quartile)	0.58	(0.06-1.29)	0.49	(0.06-1.36)	2.60	(1.02-6.64)^a	2.66	(1.02-6.94)^a
(4^thvs 1^st quartile)	0.63	(0.19-2.08)	0.60	(0.18-2.01)	2.60	(1.01-6.66)^a	2.59	(1.01-6.76)^a
Log HOMA β-cell (2^ndvs 1^st quartile)	1.16	(0.35-3.80)	1.27	(0.38-4.25)	0.35	(0.08-1.55)	0.45	(0.10-2.03)
(3^rdvs 1^st quartile)	0.52	(0.11-2.43)	0.51	(0.11-2.39)	0.16	(0.02-1.23)	0.17	(0.02-1.35)
(4^thvs 1^st quartile)	0.25	(0.03-2.97)	0.22	(0.03-1.73)	0.17	(0.02-1.28)	0.16	(0.02-1.21)

^aP＜0.05.

Citation: Liu CM, Tung TH, Tsai ST, Liu JH, Tsai YK, Chen VTK, Tam TN, Lu HF, Wang KK, Hsu CT, Shih HC, Chan DC, Chou P. Serum insulin, insulin resistance, β-cell dysfunction, and gallstone disease among type 2 diabetics in Chinese population: A community-based study in Kinmen, Taiwan. World J Gastroenterol 2005; 11(45): 7159-7164
URL: https://www.wjgnet.com/1007-9327/full/v11/i45/7159.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i45.7159