Depletion of CD25+CD4+T cells (Tregs) enhances the HBV-specific CD8+ T cell response primed by DNA immunization

Figure 3 Frequency of HBV-specific CD8⁺ T cells induced by DNA immunization. The frequency of S28-39-specific CD8⁺ T cells was detected by DimerX staining and intracellular IFN-γ staining as described in Figure 2. The data (mean±SD of PBMCs from six mice) show the percentages of DimerX positive or IFN-γ producing cells in the CD8⁺ cell population (A and B). The data presented are representative of three individual experiments n = 6.