Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats

Figure 3 Analysis of liver histopathology and immunohistochemistry in rats induced with CCl₄. A: Paraffin/saline; B: CCl₄×6 wk; C: CCl₄/MSCs; D: CCl₄/saline; 1: HE staining, original magnification ×100; 2: MT staining, original magnification ×40; 3: immunohistochemistry for α-SMA, DAB staining, original magnification ×400; E: MT and α-SMA staining was quantified using IBAS 2.5 software. Data represent the fold-increase in positive staining vs paraffin/saline. Values are presented as mean±SD. ^bP<0.01 vs CCl₄/saline. Not significantly different between values of CCl₄/saline and CCl₄×6 wk.