Rat bone marrow mesenchymal stem cells differentiate into hepatocytes in vitro

Table 1 Concentration of AFP, albumin and urea in the medium at different time points (mean±SE).

Group	3 d	6 d	9 d	12 d	15 d	18 d	21 d	24 d
AFP (µg/L)
Differentiation	12.1±1.2	11.7±0.8	14.4±2.1	15.5±1.4a	24.5±2.9b	25.9±3.0b	46.2±1.5b	24.8±2.2b
Control	11.5±0.9	11.6±1.2	12.6±2.4	13.4±1.9	12.8±1.5	14.0±0.7	12.9±1.3	11.1±2.4
Albumin (µg/mL)
Differentiation	-	-	-	-	0.5±0.4	0.8±0.6	1.4±0.2b	2.1±0.7b
Control	-	-	-	-	-	0.7±0.6	0.6±0.5	0.6±0.7
Urea (mmol/L)
Differentiation	-	-	-	-	-	-	2.3±0.4b	2.6±0.9b
Control	-	-	-	-	-	-	0.6±0.5	0.5±0.5

^aP<0.05 vs control,

^bP<0.01 vs control, - stands for what could not detected, n = 6.