High level of hepatitis B virus DNA after HBeAg-to-anti-HBe seroconversion is related to coexistence of mutations in its precore and basal core promoter

Table 2 Relationship between CD-PCR results and serum HBV DNA load in 165 serum samples with detectable HBV DNA in serum after HBeAg-to-anti-HBe seroconversion.

	No. (%) of CD-PCR results
	Total G1896A	Total A1762T/G1764A	G1896A only	A1762T/G1764A only	Coexistence
Low-level group (n = 61)	53 (86.9)b	20 (32.8)	35 (57.4)d	2 ( 3.3)	18 (29.5)
Median level group (n = 58)	45 (77.6)	32 (55.2)e	23 (39.6)	10 (17.3)	22 (37.9)
High-level group (n = 46)	30 (65.2)	31 (67.4)f	6 (13.0)	7 (15.2)	24 (52.2)g

¹χ² = 7.08,

^bP<0.01, ²χ² = 21.81,

^dP<0.01, compared with high-level group. ³χ² = 6.06,

^eP<0.05, compared with low-level group. ⁴χ² = 8.20,

^fP<0.01, compared with median level group. ⁵χ² = 5.65,

^gP<0.05, compared with low-level group.