Plasma von Willebrand factor level as a prognostic indicator of patients with metastatic colorectal carcinoma

Table 2 Analysis of prognostic factors on survival.

Variables	n	Univariate(P)	Multivariate(P)
Age (yr)
<50	37	0.528	-
≥50	49
Gender
Male	56	0.986	-
Female	30
Performance status
0	50	0.022	0.014
1. 2	36
Site of primary
tumor
Colon	44	0.430	-
Rectum	42
Extent of metastases
One site	42	0.028	0.012
Multiple sites	44
Liver metastases
Present	54	0.658	-
Absent	32
Lung metastases
Present	54	0.443	-
Absent	32
Histological
differentiation
Well/moderate	57	0.718	-
Poor/unknown	29
Pre-treatment CEA
≤6 ng/mL	29	0.213	-
>6 ng/mL	57
Pre-treatment vWF
≤160%	33	<0.001	<0.001
>160%	53

CEA, carcinoembryonic antigen; vWF: von Willebrand factor; -: no significance.