Inhibition of DNA primase and induction of apoptosis by 3,3’-diethyl-9-methylthia-carbocyanine iodide in hepatocellular carcinoma BEL-7402 cells

Figure 11 Inhibition of DMTCCI on activity of Caspase-3 in BEL-7402 cells. BEL-7402 cells were harvested after exposure to 8 μmol/L of DMTCCI for indicated time. Activity of Caspase-3 was measured by ApoAlert caspase-3 assay kits. Cell lysates were prepared for each sample and used in the Caspase-3 ac-tivity assay using the colorimetric substrate DEVD-pNA. Ab-sorbance was read at 410 nm and This figure is a representa-tive of three experiments.