Anti-neoplastic efficacy of Haimiding on gastric carcinoma and its mechanisms

Table 2 Effect of HMD on formation of colonies in culture of BGC-823, E_ca-109 and HCT-8 cell lines (n = 8)

Drug	Percentage of colony formation (mean ± SD)
	Dose (mg/ml)	BGC-823	HCT-8	Eca-109
HMD	10.00	72.18 ± 7.29c	83.18 ± 9.01	61.58 ± 4.12a
HMD	20.00	50.21 ± 5.18d	59.45 ± 6.78c	22.43 ± 3.65d
HMD	40.00	28.43 ± 3.42d	30.15 ± 4.20d	0
5-Fu	0.04	61.18 ± 4.27c	68.70 ± 5.15a	69.27 ± 5.48a
HMD without 5-Fu	19.63	90.51 ± 7.42	82.15 ± 7.92	78.29 ± 6.25a
Blank control		98.27 ± 6.58	95.68 ± 9.12	97.14 ± 8.26c

^aP < 0.05, ^bP < 0.01 vs blank control;

^cP < 0.05,

^dP < 0.01 vs HMD without 5-Fu.