Yeast expression and DNA immunization of hepatitis B virus S gene with second-loop deletion of &alpha; determinant region

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 10, Issue 20

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

All Articles published online

Item

Count

PDF

217

HTML

2127

Figures (1-4)

210

Tables (1-2)

239

Sum=2793

Oct 15, 2004 (publication date) through Sep 19, 2024

Times Cited of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Oct 15, 2004; 10(20): 2989-2993
Published online Oct 15, 2004. doi: 10.3748/wjg.v10.i20.2989

Table 2 Antigenicity of HBsAg with second-loop deletion of α determinant

Groups	HBsAg titer by IMx S/CO value	Anti-HBs responses in DNA immunization
Groups	HBsAg titer by IMx S/CO value	Positive rate	mIU/L (GMT ± SE)
Empty control	-	0/5	-
pcDNA3	-	0/5	-
pHB	1 589 ± 234.5^b	6/10	27.60 ± 17.3^c
pHB-SD	106 ± 26.8	2/10	4.56 ± 3.52

S/CO: the ratio of sample against cut off value. GMT: geomet-ric mean titer.

^bP < 0.01, t = 5.02 vs groups of pHB-SD;

^cP = 0.02, t = 2.7 vs groups of pHB-SD.

Citation: Hu H, Peng XM, Huang YS, Gu L, Xie QF, Gao ZL. Yeast expression and DNA immunization of hepatitis B virus S gene with second-loop deletion of α determinant region. World J Gastroenterol 2004; 10(20): 2989-2993
URL: https://www.wjgnet.com/1007-9327/full/v10/i20/2989.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i20.2989