Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO

doi:10.3748/wjg.v10.i15.2205

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Aug 1, 2004 (publication date) through Apr 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Aug 1, 2004; 10(15): 2205-2208
Published online Aug 1, 2004. doi: 10.3748/wjg.v10.i15.2205

Table 2 Effect of honokiol on cell cycle distribution and apoptosis in RKO cells

Treatment(μg/mL)	Cell cycle distribution (%)			Apoptosis (%)
Treatment(μg/mL)	G0/G1	S	G2/M	Apoptosis (%)
Control	44.76	45.09	10.14	0.21
5	48.03	42.37	9.60	4.51
10	54.04	40.30	5.66	14.10^b
15	58.94	39.36	1.70	20.31^d

Cell cycle distribution was determined after 48 h of treatment in each group. The tabulated percentages were an average calculated on the results of three separate experiments.

^bP < 0.01,

^dP < 0.01 vs corresponding control group.

Citation: Wang T, Chen F, Chen Z, Wu YF, Xu XL, Zheng S, Hu X. Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO. World J Gastroenterol 2004; 10(15): 2205-2208
URL: https://www.wjgnet.com/1007-9327/full/v10/i15/2205.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i15.2205