Loss of heterozygosity on chromosome 10q22-10q23 and 22q11.2-22q12.1 and p53 gene in primary hepatocellular carcinoma

Table 2 Clinical and genetic features of 20 patients with HCC (*, LOH; △, homozygous deletion; O, no deletion; +, HBsAg positive; -, HBsAg negative)

Case No.	Age (yr)	Sex	HBsAg	TP53.A	TP53.B	TP53.G	D10S579	D22S421
1	49	M	+	*	*	O	*	O
2	55	M	+	O	△	O	O	△
3	39	M	+	O	△	O	△	△
4	55	F	+	*	O	O	O	*
5	72	F	+	O	*	△	△	O
6	40	M	+	O	O	O	O	O
7	34	F	+	O	*	O	△	△
8	56	M	+	O	O	O	O	O
9	27	F	-	O	*	O	△	O
10	50	M	+	O	O	O	O	△
11	48	M	+	O	△	O	△	△
12	52	M	+	O	O	O	△	O
13	63	F	+	O	△	△	△	△
14	60	M	+	O	△	O	*	△
15	65	M	+	O	O	O	*	O
16	34	M	+	O	*	O	O	O
17	64	M	+	*	*	O	*	*
18	52	F	+	O	O	O	△	O
19	32	F	+	O	△	O	O	△
20	38	M	+	*	O	O	O	*
LOH rate (%)				20	30	0	20	15
Homozygous deletion rate (%)				0	30	10	40	40