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Copyright ©The Author(s) 2018.
World J Gastroenterol. Aug 21, 2018; 24(31): 3521-3530
Published online Aug 21, 2018. doi: 10.3748/wjg.v24.i31.3521
Figure 1
Figure 1 Ischemia-reperfusion injury: A complex multifactorial process that causes cell damage during liver transplantation. While the oxygen deprivation due to ischemia depletes cell energy, subsequent reoxygenation due to reperfusion induces many cascades, from production of reactive oxygen species to initiation of apoptosis. UPS: Ubiquitin-proteasome system; mPTP: mitochondrial permeability transition pore.