Caecal pH is a biomarker of excessive colonic fermentation

Figure 1 A typical wireless motility capsule trace demonstrating temperature (blue line), pH (green line) and contractility (red line) across the ileo-caecal junction. The pH drop was defined as the difference between the stable ileal pH and the caecal pH nadir. ICJ: Ileo-caecal junction.

Figure 2 Differences (mean ± SD) in ileal, caecal and ileo-caecal junction pH drop between patients and controls. Caecal pH significantly lower in patients than in controls and pH drop across the ICJ was lower in patients than in controls. ^bP < 0.01 vs patients group. ICJ: Ileo-caecal junction.

Figure 3 Caecal pH and caecal contractility was positively correlated (r = 0. 54, P = 0.002). AUC: Area under the curve.