Serum interleukin-1 receptor antagonist is an early indicator of colitis onset in Gαi2-deficient mice

Figure 1 A: Serum IL-18 concentrations in 24-wk-old Gαi2-deficient mice (n = 9) and their heterozygous littermates (controls; n = 7). Data were analyzed using the non-parametric Mann-Whitney U test. A value of P ≤ 0.05 was regarded as statistically significant. The horizontal bars mark the median values within each group; B: Serum IL-1Ra concentrations in 6-wk-old (healthy; n = 11), 12-wk-old (pre-colitic; n = 8), and 24-wk-old (colitic; n = 7) Gαi2-deficient mice and their heterozygous controls (n = 10). Data were analyzed using the non-parametric Mann-Whitney U test. A value of P ≤ 0.05 was regarded as statistically significant. The horizontal bars mark the median values within each group.