Molecular therapy for hepatic injury and fibrosis: Where are we?

doi:10.3748/wjg.v12.i4.509

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Jan 28, 2006 (publication date) through Apr 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2006; 12(4): 509-515
Published online Jan 28, 2006. doi: 10.3748/wjg.v12.i4.509

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Figure 1 Strategies for the prevention and treatment of hepatic fibrosis. A simplified version of the pathogenesis of hepatic fibrosis is illustrated schematically. At various stages, possible therapeutic strategies are provided in italics. See the text for details. KC = Kupffer cells; ECM = extracellular matrix; HSC = hepatic stellate cells; PDGF = platelet-derived growth factor; ROS = reactive oxygen species; TNF-α = tumor necrosis factor-α; TGF-β = transforming growth factor-β.

Citation: Prosser CC, Yen RD, Wu J. Molecular therapy for hepatic injury and fibrosis: Where are we? World J Gastroenterol 2006; 12(4): 509-515
URL: https://www.wjgnet.com/1007-9327/full/v12/i4/509.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i4.509