Lymphatic metastasis and nm23H1 genetic instability in Chinese colon cancer patients

Figure 1 Expression of ICAM-1 in lymphatic endothelial cells. A: Negative expression of ICAM-1 in the lymphatic endothelium (L) of normal colon and positive expression of ICAM-1 in blood vessel endothelium (arrow) (Envision, original magnification × 400); B: Positive expression of ICAM-1 in the lymphatic endothelium (arrow) of colon cancer (Ca) (Envision, original magnifi-cation × 400).

Figure 2 Positive D17S396 MSI, LOH and nm23H₁ in 30 cases of colon cancer. A: Positive MSI (arrow-headed) with an additional allele band (1C) compared with normal tissue (1N); B: Positive MSI (arrow-headed) with a removed allele band (4C) compared with normal tissue (4N); C: Positive LOH (arrow-headed) with a lacked allele band (9C) compared with normal tissue (9N); D: Positive nm23H₁ protein (arrow-headed) in cytoplasm, and nucleoli and membranes (Envision, original magnification × 200).