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For: Song NN, Li QS, Liu CX. Intestinal permeability of metformin using single-pass intestinal perfusion in rats. World J Gastroenterol 2006; 12(25): 4064-4070 [PMID: 16810761 DOI: 10.3748/wjg.v12.i25.4064]
URL: https://www.wjgnet.com/1007-9327/full/v12/i25/4064.htm
Number Citing Articles
1
Xiao-yan Zeng, Shu Dong, Nan-nan He, Chun-jie Jiang, Yue Dai, Yu-feng Xia. Comparative pharmacokinetics of arctigenin in normal and type 2 diabetic rats after oral and intravenous administrationFitoterapia 2015; 105: 119 doi: 10.1016/j.fitote.2015.06.014
2
Jin-Ah Lee, Sang Keun Ha, Young-Chan Kim, Inwook Choi. Effects of friedelin on the intestinal permeability and bioavailability of apigeninPharmacological Reports 2017; 69(5): 1044 doi: 10.1016/j.pharep.2017.04.012
3
Camilla Sander, Hanne Mørck Nielsen, Jette Jacobsen. Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancementInternational Journal of Pharmaceutics 2013; 458(2): 254 doi: 10.1016/j.ijpharm.2013.10.026
4
Tugba Gulsun, Nihan Izat, Selma Sahin. Influence of permeability enhancers on the paracellular permeability of metformin hydrochloride and furosemide across Caco-2 cellsCanadian Journal of Physiology and Pharmacology 2023; 101(4): 185 doi: 10.1139/cjpp-2022-0265
5
John R. Crison, Peter Timmins, Anther Keung, Vijay V. Upreti, David W. Boulton, Barry J. Scheer. Biowaiver Approach for Biopharmaceutics Classification System Class 3 Compound Metformin Hydrochloride Using In Silico ModelingJournal of Pharmaceutical Sciences 2012; 101(5): 1773 doi: 10.1002/jps.23063
6
Bo Feng, Manthena V Varma, Chester Costales, Hui Zhang, Larry Tremaine. In vitroandin vivoapproaches to characterize transporter-mediated disposition in drug discoveryExpert Opinion on Drug Discovery 2014; 9(8): 873 doi: 10.1517/17460441.2014.922540
7
Jinling Wang, Lin Li, Yuqian Du, Jin Sun, Xiaopeng Han, Cong Luo, Xiaoyu Ai, Qi Zhang, Yongjun Wang, Qiang Fu, Zhifu Yang, Zhonggui He. Improved Oral Absorption of Doxorubicin by Amphiphilic Copolymer of Lysine-Linked Ditocopherol Polyethylene Glycol 2000 Succinate: In Vitro Characterization and in Vivo EvaluationMolecular Pharmaceutics 2015; 12(2): 463 doi: 10.1021/mp500833m
8
Yang Mai, Francisco Afonso-Pereira, Sudaxshina Murdan, Abdul W. Basit. Excipient-mediated alteration in drug bioavailability in the rat depends on the sex of the animalEuropean Journal of Pharmaceutical Sciences 2017; 107: 249 doi: 10.1016/j.ejps.2017.07.009
9
Yoo-Seong Jeong, William J. Jusko. Meta-Assessment of Metformin Absorption and Disposition Pharmacokinetics in Nine SpeciesPharmaceuticals 2021; 14(6): 545 doi: 10.3390/ph14060545
10
J. D. Yuvenesan Jagabalan, Vikneswaran Murugaiyah, Hadzliana Zainal, Sharif Mahsufi Mansor, Surash Ramanathan. Intestinal permeability of mitragynine in rats using in situ absorption modelJournal of Asian Natural Products Research 2019; 21(4): 351 doi: 10.1080/10286020.2018.1461088
11
Yan Gao, Yuqiang Wang, Yukun Ma, Aihua Yu, Fengqun Cai, Wei Shao, Guangxi Zhai. Formulation optimization and in situ absorption in rat intestinal tract of quercetin-loaded microemulsionColloids and Surfaces B: Biointerfaces 2009; 71(2): 306 doi: 10.1016/j.colsurfb.2009.03.005
12
Kuei‐Yu Chien, Ku‐Fu Hsu, Hsin‐I Lo, Ryh‐Nan Pan, Chia‐Hua Kuo, Fu‐An Chen, Mei‐Chich Hsu. Effects of swimming on the pharmacokinetics and glucose tolerance of metformin in insulin‐resistant ratsBiopharmaceutics & Drug Disposition 2008; 29(5): 300 doi: 10.1002/bdd.615
13
Soung Baek Jang, Dongju Kim, Seong Yeon Kim, Changhee Park, Ji Hoon Jeong, Hyo-Jeong Kuh, Jaehwi Lee. Impact of Micellar Vehicles onin situIntestinal Absorption Properties of Beta-Lapachone in RatsThe Korean Journal of Physiology & Pharmacology 2013; 17(1): 9 doi: 10.4196/kjpp.2013.17.1.9
14
Chunxi Liu, Donghua Liu, Fan Bai, Jian Zhang, Na Zhang. In vitro and in vivo studies of lipid-based nanocarriers for oral N3-o-toluyl-fluorouracil deliveryDrug Delivery 2010; 17(5): 352 doi: 10.3109/10717541003762839
15
Eunjung Shin, Naree Shin, Ju-Hee Oh, Young-Joo Lee. High-Dose Metformin May Increase the Concentration of Atorvastatin in the Liver by Inhibition of Multidrug Resistance–Associated Protein 2Journal of Pharmaceutical Sciences 2017; 106(4): 961 doi: 10.1016/j.xphs.2016.11.020
16
Arik Dahan, Daniel Porat, Milica Markovic, Moran Zur, Olga Kister, Peter Langguth. Optimized In Silico Modeling of Drug Absorption after Gastric Bypass: The Case of MetforminPharmaceutics 2021; 13(11): 1873 doi: 10.3390/pharmaceutics13111873
17
Caleb J. Kelly, Andrew A. Verdegaal, Brent W. Anderson, William L. Shaw, Natasha A. Bencivenga-Barry, Ewa Folta-Stogniew, Andrew L. Goodman. Metformin inhibits digestive proteases and impairs protein digestion in miceJournal of Biological Chemistry 2023; 299(12): 105363 doi: 10.1016/j.jbc.2023.105363
18
Fatima Zohra Dahmani, Hui Yang, Jianping Zhou, Jing Yao, Ting Zhang, Qiang Zhang. Enhanced oral bioavailability of paclitaxel in pluronic/LHR mixed polymeric micelles: Preparation, in vitro and in vivo evaluationEuropean Journal of Pharmaceutical Sciences 2012; 47(1): 179 doi: 10.1016/j.ejps.2012.05.015
19
Sarah J. Hemauer, Svetlana L. Patrikeeva, Tatiana N. Nanovskaya, Gary D.V. Hankins, Mahmoud S. Ahmed. Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metforminAmerican Journal of Obstetrics and Gynecology 2010; 202(4): 383.e1 doi: 10.1016/j.ajog.2010.01.035
20
I.S. Song, M.K. Choi, W.S. Shim, C.K. Shim. Transport of organic cationic drugs: Effect of ion-pair formation with bile salts on the biliary excretion and pharmacokineticsPharmacology & Therapeutics 2013; 138(1): 142 doi: 10.1016/j.pharmthera.2013.01.006
21
Rong Shi, Zhangyao Xu, Xining Xu, Jingyi Jin, Yining Zhao, Tianming Wang, Yuanyuan Li, Yueming Ma. Organic cation transporter and multidrug and toxin extrusion 1 co-mediated interaction between metformin and berberineEuropean Journal of Pharmaceutical Sciences 2019; 127: 282 doi: 10.1016/j.ejps.2018.11.010
22
Mahendra Kumar Hidau, Yeshwant Singh, Shio Kumar Singh. Intestinal Permeability and Role of P-Glycoprotein in Intestinal Absorption of Novel Triethylamine Containing Thiophene S006–830 Using Single-Pass Intestinal Perfusion in RatsInternational Journal of Pharmacokinetics 2017; 2(3): 163 doi: 10.4155/ipk-2017-0003
23
Melissa Metry, Yan Shu, Bertil Abrahamsson, Rodrigo Cristofoletti, Jennifer B. Dressman, D.W. Groot, Alan Parr, Peter Langguth, Vinod P. Shah, Tomokazu Tajiri, Mehul U. Mehta, James E. Polli. Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Metformin HydrochlorideJournal of Pharmaceutical Sciences 2021; 110(4): 1513 doi: 10.1016/j.xphs.2021.01.011
24
Yeshwant Singh, Mahendra Kumar Hidau, Jampala Krishna, Shio Kumar Singh. Combined effect of rifampicin-induced P-glycoprotein expression and lipopolysaccharide-induced intestinal sepsis on the effective permeability and pharmacokinetics of an anti-malarial candidate CDRI 97/78 in ratsXenobiotica 2015; 45(8): 731 doi: 10.3109/00498254.2015.1017548
25
Basanth Babu Eedara, Mradul Kankane, Raju Jukanti, Vijay Kumar Nagabandi, Suresh Bandari. Enhanced solubility and permeability of exemestane solid dispersion powders for improved oral deliveryJournal of Pharmaceutical Investigation 2013; 43(3): 229 doi: 10.1007/s40005-013-0069-0
26
William R. Proctor, Xin Ming, David Bourdet, Tianxiang (Kevin) Han, Ruth S. Everett, Dhiren R. Thakker. Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative HypothesisJournal of Pharmaceutical Sciences 2016; 105(2): 484 doi: 10.1016/j.xphs.2015.11.040
27
Rajneet Kaur Khurana, Balan Louis Gaspar, Gail Welsby, O. P. Katare, Kamalinder K. Singh, Bhupinder Singh. Improving the biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled phosholipidic nano-mixed micellar systemsDrug Delivery and Translational Research 2018; 8(3): 617 doi: 10.1007/s13346-018-0498-4
28
Yan Zhou, Yang Jiao, Yu-Hui Wei, Guo-Rong Zhang, Jian-Ping Zhang, Jiang-Xia Ren, Fan Zhang, Guo-Qiang Zhang, Hao-Gang Duan, Xin-An Wu. Effects of pyridoxine on the intestinal absorption and pharmacokinetics of isoniazid in ratsEuropean Journal of Drug Metabolism and Pharmacokinetics 2013; 38(1): 5 doi: 10.1007/s13318-012-0106-9
29
S. Parthasarathi, J. Anu Bhushani, C. Anandharamakrishnan. Engineered small intestinal system as an alternative to in-situ intestinal permeability modelJournal of Food Engineering 2018; 222: 110 doi: 10.1016/j.jfoodeng.2017.11.019
30
Mohammad Mahmoudian, Hadi Valizadeh, Parvin Zakeri-Milani. Bortezomib-loaded solid lipid nanoparticles: preparation, characterization, and intestinal permeability investigationDrug Development and Industrial Pharmacy 2018; 44(10): 1598 doi: 10.1080/03639045.2018.1483385
31
Sandra Cvijić, Jelena Parojčić, Peter Langguth. Viscosity-mediated negative food effect on oral absorption of poorly-permeable drugs with an absorption window in the proximal intestine: In vitro experimental simulation and computational verificationEuropean Journal of Pharmaceutical Sciences 2014; 61: 40 doi: 10.1016/j.ejps.2014.04.008
32
Rajneet Kaur Khurana, Arvind K. Bansal, Sarwar Beg, Andrea Julie Burrow, O.P. Katare, Kamalinder K. Singh, Bhupinder Singh. Enhancing biopharmaceutical attributes of phospholipid complex-loaded nanostructured lipidic carriers of mangiferin: Systematic development, characterization and evaluationInternational Journal of Pharmaceutics 2017; 518(1-2): 289 doi: 10.1016/j.ijpharm.2016.12.044
33
Xin He, Zi-Jing Song, Cui-Ping Jiang, Chun-Feng Zhang. Absorption Properties of Luteolin and Apigenin in Genkwa Flos Using In Situ Single-Pass Intestinal Perfusion System in the RatThe American Journal of Chinese Medicine 2017; 45(08): 1745 doi: 10.1142/S0192415X1750094X
34
Mirko Koziolek, Patrick Augustijns, Constantin Berger, Rodrigo Cristofoletti, David Dahlgren, Janneke Keemink, Pär Matsson, Fiona McCartney, Marco Metzger, Mario Mezler, Janis Niessen, James E. Polli, Maria Vertzoni, Werner Weitschies, Jennifer Dressman. Challenges in Permeability Assessment for Oral Drug Product DevelopmentPharmaceutics 2023; 15(10): 2397 doi: 10.3390/pharmaceutics15102397
35
Darta Maija Zake, Janis Kurlovics, Linda Zaharenko, Vitalijs Komasilovs, Janis Klovins, Egils Stalidzans, Jed N. Lampe. Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissuesPLOS ONE 2021; 16(4): e0249594 doi: 10.1371/journal.pone.0249594
36
Min-Koo Choi, Im-Sook Song. Blockade of P-Glycoprotein Decreased the Disposition of Phenformin and Increased Plasma Lactate LevelBiomolecules & Therapeutics 2016; 24(2): 199 doi: 10.4062/biomolther.2015.087
37
Prasad Neerati, Dinesh Ganji, Sathish Kumar Bedada. Study on in situ and in vivo absorption kinetics of phenytoin by modulating P-glycoprotein with verapamil in ratsEuropean Journal of Pharmaceutical Sciences 2011; 44(1-2): 27 doi: 10.1016/j.ejps.2011.05.005
38
Teruo Murakami. Absorption sites of orally administered drugs in the small intestineExpert Opinion on Drug Discovery 2017; 12(12): 1219 doi: 10.1080/17460441.2017.1378176
39
Jing Cui, Bo Yu, Yu Zhao, Weiwei Zhu, Houli Li, Hongxiang Lou, Guangxi Zhai. Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systemsInternational Journal of Pharmaceutics 2009; 371(1-2): 148 doi: 10.1016/j.ijpharm.2008.12.009
40
Zhenhai Zhang, Yan Chen, Jin Deng, Xiaobin Jia, Jianping Zhou, Huixia Lv. Solid dispersion of berberine–phospholipid complex/TPGS 1000/SiO2: preparation, characterization and in vivo studiesInternational Journal of Pharmaceutics 2014; 465(1-2): 306 doi: 10.1016/j.ijpharm.2014.01.023
41
Xinru Li, Xucheng Hou, Weiming Ding, Shuangchen Cong, Yuanyuan Zhang, Mengmeng Chen, Yansha Meng, Jiongxi Lei, Yan Liu, Guiling Li. Sirolimus-loaded polymeric micelles with honokiol for oral deliveryJournal of Pharmacy and Pharmacology 2015; 67(12): 1663 doi: 10.1111/jphp.12482
42
Lina Zhao, Li He, Yuan Chen, Tongchao Xia, Le Li, Shengyan Wang, Xu Bao, Junyi Yang. Physicochemical Characterization and Biopharmaceutical Evaluation of ZWF: A Novel Anticancer Drug for the Treatment of Non-small Cell Lung CancerAAPS PharmSciTech 2021; 22(6) doi: 10.1208/s12249-021-02084-w
43
Basanth Babu Eedara, Prabhakar Reddy Veerareddy, Raju Jukanti, Suresh Bandari. Improved oral bioavailability of fexofenadine hydrochloride using lipid surfactants:ex vivo, in situandin vivostudiesDrug Development and Industrial Pharmacy 2014; 40(8): 1030 doi: 10.3109/03639045.2013.801984
44
NR Dudhipala, SR Ettireddy, GR Puchakayala. Attenuation of lipid levels in triton induced hyperlipidemia rats through rosuvastatin calcium nanoparticles: Pharmacokinetic and pharmacodynamic studiesChemistry and Physics of Lipids 2021; 237: 105081 doi: 10.1016/j.chemphyslip.2021.105081
45
Takashi Uematsu, Hideo Masuki, Masayuki Nakamura, Hideo Kawabata, Yutaka Kitamura, Taisuke Watanabe, Takao Watanabe, Tomoharu Mochizuki, Takashi Ushiki, Tomoyuki Kawase. Metformin-suppressed platelet's function in vitro: Possible relation to delayed or failure of platelet-rich fibrin preparationToxicology in Vitro 2023; 93: 105692 doi: 10.1016/j.tiv.2023.105692
46
Yong-Qiang Shan, Gang Ren, Yan-Xiang Wang, Jing Pang, Zhi-Yun Zhao, Jing Yao, Xue-Fu You, Shu-Yi Si, Dan-Qing Song, Wei-Jia Kong, Jian-Dong Jiang. Berberine analogue IMB-Y53 improves glucose-lowering efficacy by averting cellular efflux especially P-glycoprotein effluxMetabolism 2013; 62(3): 446 doi: 10.1016/j.metabol.2012.09.009
47
I.R. Dubbelboer, D. Dahlgren, E. Sjögren, H. Lennernäs. Rat intestinal drug permeability: A status report and summary of repeated determinationsEuropean Journal of Pharmaceutics and Biopharmaceutics 2019; 142: 364 doi: 10.1016/j.ejpb.2019.07.005
48
Investigation of the Functional Role of P-Glycoprotein in Limiting the Oral Bioavailability of LumefantrineAntimicrobial Agents and Chemotherapy 2014; 58(1): 489 doi: 10.1128/AAC.01382-13
49
Adam S. Darwich, Kathryn Henderson, Angela Burgin, Nicola Ward, Janet Whittam, Basil J. Ammori, Darren M. Ashcroft, Amin Rostami‐Hodjegan. Trends in oral drug bioavailability following bariatric surgery: examining the variable extent of impact on exposure of different drug classesBritish Journal of Clinical Pharmacology 2012; 74(5): 774 doi: 10.1111/j.1365-2125.2012.04284.x
50
YH Choi, U Lee, BK Lee, MG Lee. Pharmacokinetic interaction between itraconazole and metformin in rats: competitive inhibition of metabolism of each drug by each other via hepatic and intestinal CYP3A1/2British Journal of Pharmacology 2010; 161(4): 815 doi: 10.1111/j.1476-5381.2010.00913.x
51
Swati Jaiswal, Mahendra Shukla, Abhisheak Sharma, Nagarjun Rangaraj, Kalpesh Vaghasiya, Mohd Yaseen Malik, Jawahar Lal. Preclinical pharmacokinetics and ADME characterization of a novel anticancer chalcone, cardamoninDrug Testing and Analysis 2017; 9(8): 1124 doi: 10.1002/dta.2128
52
Shuai Li, Yuanhong Wang, Tingfu Jiang, Han Wang, Shuang Yang, Zhihua Lv. Absorption and Transport of Sea Cucumber Saponins from Apostichopus japonicusMarine Drugs 2016; 14(6): 114 doi: 10.3390/md14060114
53
Xiaoyou Qu, Yang Zou, Chuyu He, Yuanhang Zhou, Yao Jin, Yunqiang Deng, Ziqi Wang, Xinru Li, Yanxia Zhou, Yan Liu. Improved intestinal absorption of paclitaxel by mixed micelles self-assembled from vitamin E succinate-based amphiphilic polymers and their transcellular transport mechanism and intracellular trafficking routesDrug Delivery 2018; 25(1): 210 doi: 10.1080/10717544.2017.1419513
54
Khalil Sakeer, Pompilia Ispas-Szabo, Mircea Alexandru Mateescu. Self-Stabilizing Ampholytic Starch Excipients for Sustained Release of Highly Soluble Drugs: the Case Study of MetforminAAPS PharmSciTech 2017; 18(7): 2658 doi: 10.1208/s12249-017-0723-3
55
Yuan Chen, Xiaowei Jin, Yanhui Kuang, Sisi Zhang, Chuanping Zhang, Chuyuan Li, Bohong Guo. A Novel Oral Drugs Delivery System for Borneol Based on HiCap®100 and Maltodextrin: Preparation, Characterization, and the Investigation as an Intestinal Absorption EnhancerAAPS PharmSciTech 2023; 24(7) doi: 10.1208/s12249-023-02654-0
56
Maria Pau García-Moll, Llucia García-Moll, Enrique Javier Carrasco-Correa, Miquel Oliver, Ernesto Francisco Simó-Alfonso, Manuel Miró. Biomimetic Dispersive Solid-Phase Microextraction: A Novel Concept for High-Throughput Estimation of Human Oral Absorption of Organic CompoundsAnalytical Chemistry 2023; 95(35): 13123 doi: 10.1021/acs.analchem.3c01749
57
Maria Manconi, Amparo Nácher, Virginia Merino, Matilde Merino-Sanjuan, Maria Letizia Manca, Carla Mura, Simona Mura, Anna Maria Fadda, Octavio Diez-Sales. Improving Oral Bioavailability and Pharmacokinetics of Liposomal Metformin by Glycerolphosphate–Chitosan MicrocomplexationAAPS PharmSciTech 2013; 14(2): 485 doi: 10.1208/s12249-013-9926-4
58
M. Bouchoucha, B. Uzzan, R. Cohen. Metformin and digestive disordersDiabetes & Metabolism 2011; 37(2): 90 doi: 10.1016/j.diabet.2010.11.002
59
William R. Proctor, David L. Bourdet, Dhiren R. Thakker. Mechanisms Underlying Saturable Intestinal Absorption of MetforminDrug Metabolism and Disposition 2008; 36(8): 1650 doi: 10.1124/dmd.107.020180
60
Parvin Zakeri-Milani, Ziba Islambulchilar, Fatemeh Majidpour, Ensieh Jannatabadi, Farzaneh Lotfipour, Hadi Valizadeh. A study on enhanced intestinal permeability of clarithromycin nanoparticlesBrazilian Journal of Pharmaceutical Sciences 2014; 50(1): 121 doi: 10.1590/S1984-82502011000100012
61
Ju Hun Yeon, Je-Kyun Park. Drug Permeability Assay Using Microhole-Trapped Cells in a Microfluidic DeviceAnalytical Chemistry 2009; 81(5): 1944 doi: 10.1021/ac802351w
62
Hadi Valizadeh, Hadi Fahimfar, Saeed Ghanbarzadeh, Ziba Islambulchilar, Parvin Zakeri-Milani. Effect of anionic macromolecules on intestinal permeability of furosemideDrug Development and Industrial Pharmacy 2015; 41(2): 190 doi: 10.3109/03639045.2013.851210
63
Victoria O. Oyanna, Kenisha Y. Garcia-Torres, Baron J. Bechtold, Katherine D. Lynch, M. Ridge Call, Miklós Horváth, Preston K. Manwill, Tyler N. Graf, Nadja B. Cech, Nicholas H. Oberlies, Mary F. Paine, John D. Clarke. Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in MiceDrug Metabolism and Disposition 2023; 51(11): 1483 doi: 10.1124/dmd.123.001360
64
Noritaka Nakamichi, Hiroyo Shima, Satoshi Asano, Takahiro Ishimoto, Tomoko Sugiura, Kazuki Matsubara, Hiroyuki Kusuhara, Yuichi Sugiyama, Yoshimichi Sai, Ken-ichi Miyamoto, Akira Tsuji, Yukio Kato. Involvement of Carnitine/Organic Cation Transporter OCTN1/SLC22A4 in Gastrointestinal Absorption of MetforminJournal of Pharmaceutical Sciences 2013; 102(9): 3407 doi: 10.1002/jps.23595
65
Hong Li, Meirong Huo, Jianping Zhou, Yindi Dai, Yaping Deng, Xiangjie Shi, Jumah Masoud. Enhanced Oral Absorption of Paclitaxel in N-Deoxycholic Acid-N, O-Hydroxyethyl Chitosan Micellar SystemJournal of Pharmaceutical Sciences 2010; 99(11): 4543 doi: 10.1002/jps.22159
66
Michael P White, Mariana Babayeva, David R Taft, Manoj Maniar. Determination of intestinal permeability of rigosertib (ON 01910.Na, Estybon): correlation with systemic exposureJournal of Pharmacy and Pharmacology 2013; 65(7): 960 doi: 10.1111/jphp.12057
67
Dominik Schreiber, Lisa Marx, Silke Felix, Jasmin Clasohm, Maximilian Weyland, Maximilian Schäfer, Markus Klotz, Rainer Lilischkis, Gerhard Erkel, Karl-Herbert Schäfer. Anti-inflammatory Effects of Fungal Metabolites in Mouse Intestine as Revealed by In vitro ModelsFrontiers in Physiology 2017; 8 doi: 10.3389/fphys.2017.00566