Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Artif Intell Gastroenterol. Feb 28, 2022; 3(1): 21-27
Published online Feb 28, 2022. doi: 10.35712/aig.v3.i1.21
Artificial intelligence and human liver allocation: Potential benefits and ethical implications
Marcos Mucenic, Ajacio Bandeira de Mello Brandão, Claudio Augusto Marroni
Marcos Mucenic, Liver Transplant Adult Group, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90020-090, RS, Brazil
Ajacio Bandeira de Mello Brandão, Claudio Augusto Marroni, Hepatology, Universidade Federal de Ciencias da Saude de Porto Alegre, Porto Alegre 90050-170, RS, Brazil
Author contributions: de Mello Brandão AB wrote about liver allocation; Marroni CA wrote about artificial intelligence; Mucenic M wrote about the applications of artificial intelligence on liver allocation and on the prediction of waiting list mortality, wrote abstract and conclusions, and revised the writing style; all three writers revised the paper.
Conflict-of-interest statement: There is no conflict of interest associated with any of the authors of this manuscript
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Marcos Mucenic, MD, PhD, Doctor, Medical Assistant, Liver Transplant Adult Group, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Av. Independencia, 75, Porto Alegre 90020-090, RS, Brazil.
Received: December 24, 2021
Peer-review started: December 24, 2021
First decision: January 26, 2022
Revised: February 13, 2022
Accepted: February 23, 2022
Article in press: February 23, 2022
Published online: February 28, 2022
Core Tip

Core Tip: This review discusses the ethical aspects and current advancements in liver allocation (LA). It summarizes the concept of artificial intelligence and focuses on the latest developments of machine learning algorithms as applied to predicting waiting list mortality and LA. To date, only a few research groups have published works on this field; they also wrote reviews on the subject. Our minireview offers a thorough and impartial view of the topic, and we hope this will alert other potential researchers to this promising field.