Evidence Review
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Oct 28, 2020; 8(5): 348-374
Published online Oct 28, 2020. doi: 10.13105/wjma.v8.i5.348
Gastrointestinal and hepatic manifestations of COVID-19 infection: Lessons for practitioners
Syed B Pasha, Ahmed Swi, Ghassan M Hammoud
Syed B Pasha, Department of Internal Medicine, University of Missouri, Columbia, MO 65212, United States
Ahmed Swi, Ghassan M Hammoud, Division of Gastroenterology and Hepatology, University of Missouri School of Medicine, Columbia, MO 65212, United States
Author contributions: Hammoud GM conceived the idea; Pasha SB and Swi A wrote the manuscript; Hammoud GM reviewed and revised the manuscript.
Conflict-of-interest statement: None of the authors have any conflict of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ghassan M Hammoud, MD, MPH Professor, Division of Gastroenterology and Hepatology, University of Missouri School of Medicine, 1 Hospital Drive, Columbia, MO 65212, United States. hammoudg@health.missouri.edu
Received: July 30, 2020
Peer-review started: July 30, 2020
First decision: September 13, 2020
Revised: September 26, 2020
Accepted: October 26, 2020
Article in press: October 26, 2020
Published online: October 28, 2020
Core Tip

Core Tip: This review is to summarize the available evidence for extrapulmonary manifestations of coronavirus disease 2019 infection, particularly emphasizing on gastrointestinal and hepatopancreatobiliary manifestations. Here we briefly discussed the possible pathophysiologic mechanism for the disease, and summarized the recommendations of multiple gastrointestinal societies regarding safe and effective clinical practice during the ongoing pandemic. Lastly, we've touched briefly upon management of chronic liver disease and transplant patients.