Meta-Analysis
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Jul 31, 2019; 7(7): 358-372
Published online Jul 31, 2019. doi: 10.13105/wjma.v7.i7.358
Effect of dl-3-n-butylphthalide on infarction volume in animal models of ischemic stroke: A meta-analysis
Di Luan, Zheng-Yu Wu, Yuan-Xiang Zhang, Li-Li Yuan, Yang Xu, Zhao-Hu Chu, Ling-Song Ma, Ya-Ping Wang, Shou-Cai Zhao
Di Luan, Li-Li Yuan, Yang Xu, Zhao-Hu Chu, Ling-Song Ma, Ya-Ping Wang, Shou-Cai Zhao, Department of Neurology, Yijishan Hospital affiliated to Wannan Medical College, Wuhu 241000, Anhui Province, China
Zheng-Yu Wu, Yuan-Xiang Zhang, Department of Clinical Pharmacy, Yijishan Hospital affiliated to Wannan Medical College, Wuhu 241000, Anhui Province, China
Author contributions: Luan D, Wu ZY, Zhang YX, Yuan LL, and Zhao SC conceived and designed the study; study searching was done by Luan D and Wu ZY. Further, studies screening and selection was done by Luan D and Wu ZY independently and disagreement was resolved by Zhao SC, Xu Y, Chu ZH, and Ma LS. Luan D and Wu ZY performed data extraction independently. Wang YP did analysis in supervision of Zhao SC. All authors were involved in interpretation of the results. The final draft of this manuscript was done by Luan D and read and approved by all the authors.
Supported by the National Natural Science Foundation of China, NO. 81701161.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The manuscript is designed as per PRISMA 2009 guideline and checklist is provided as supplementary file.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shou-Cai Zhao, MD, Doctor, Professor, Teacher, Department of Neurology, Yijishan Hospital affiliated to Wannan Medical College, Wuhu 241000, Anhui Province, China. neurozsc@wnmc.edu.cn
Telephone: +86-18505539779
Received: May 10, 2019
Peer-review started: May 14, 2019
First decision: July 26, 2019
Revised: July 27, 2019
Accepted: July 29, 2019
Article in press: July 29, 2019
Published online: July 31, 2019
Core Tip

Core tip: The systematic review of animal research is of great significance in drug development. This study reports for the first time a systematic review and meta-analysis of the effects of butylphthalide on the volume of cerebral infarction in experimental ischemic stroke.