Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Jul 31, 2019; 7(7): 350-357
Published online Jul 31, 2019. doi: 10.13105/wjma.v7.i7.350
Published online Jul 31, 2019. doi: 10.13105/wjma.v7.i7.350
Pediatric recurrent Clostridium difficile infections in immunocompetent children: Lessons learned from case reports of the first twelve consecutive patients
Angela Chu, Sonia Michail, Department of Pediatrics, Miller Children’s and Women’s Hospital, Long Beach, CA 90826, United States
Angela Chu, Sonia Michail, Department of Pediatrics, UC Irvine School of Medicine, Irvine, CA 92612, United States
Sonia Michail, Pediatric Gastroenterology, Hepatology and Nutrition Center, Miller Children’s and Women’s Hospital, Long Beach, CA 90826, United States
Sonia Michail, University of Southern California, Los Angeles, CA 92708, United States
Author contributions: Chu A and Michail S contributed equally to this work. Chu A wrote most of the manuscript, Michail S conceptualized idea and supervised work.
Conflict-of-interest statement: All the authors declare that they have no competing interests.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Sonia Michail, MD, Department of Pediatrics, 2801 Atlantic Ave, Long Beach CA 90806 United States. sonia.michail@hotmail.com
Telephone: +1-7143787230
Received: April 22, 2019
Peer-review started: April 22, 2019
First decision: June 10, 2019
Revised: June 13, 2019
Accepted: July 26, 2019
Article in press: July 26, 2019
Published online: July 31, 2019
Peer-review started: April 22, 2019
First decision: June 10, 2019
Revised: June 13, 2019
Accepted: July 26, 2019
Article in press: July 26, 2019
Published online: July 31, 2019
Core Tip
Core tip: Children with recurrent Clostridium difficile infection who do not have known immunodeficiency or inflammatory bowel disease deserve a thorough workup as many may have an underlying gastrointestinal disease.