Pal P, Mateen MA, Pooja K, Rajadurai N, Gupta R, Tandan M, Duvvuru NR. Intestinal ultrasound in Crohn’s disease: A systematic review of its role in diagnosis, monitoring, and treatment response. World J Meta-Anal 2025; 13(2): 104080 [DOI: 10.13105/wjma.v13.i2.104080]
Corresponding Author of This Article
Partha Pal, Department of Medical Gastroenterology, Asian Institute of Gastroenterology, 6-3-661 Red Rose Cafe Lane, Sangeet Nagar, Somajiguda, Hyderabad 500082, India. partha0123456789@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Systematic Reviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Meta-Anal. Jun 18, 2025; 13(2): 104080 Published online Jun 18, 2025. doi: 10.13105/wjma.v13.i2.104080
Intestinal ultrasound in Crohn’s disease: A systematic review of its role in diagnosis, monitoring, and treatment response
Partha Pal, Mohammad Abdul Mateen, Kanapuram Pooja, Nandhakumar Rajadurai, Rajesh Gupta, Manu Tandan, Nageshwar Reddy Duvvuru
Partha Pal, Kanapuram Pooja, Nandhakumar Rajadurai, Rajesh Gupta, Manu Tandan, Nageshwar Reddy Duvvuru, Department of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India
Mohammad Abdul Mateen, Department of Diagnostic Radiology and Imaging, Asian Institute of Gastroenterology, Hyderabad 500082, India
Author contributions: Pal P conceptualized the work, performed the literature search, wrote the first draft, and provided intellectual input; Mateen MA conceptualized the work, supervised the writing and critically revised the manuscript; Pooja K performed literature search, wrote the first draft and revised the manuscript; Rajadurai N performed literature search and helped in writing the first draft; Gupta R supervised the literature search, and the writing, provided intellectual input and critically revised the manuscript; Tandan M supervised the literature search, and the writing, provided intellectual input and critically revised the manuscript; Duvvuru NR supervised the writing, provided intellectual input and critically revised the manuscript.
Conflict-of-interest statement: None of the authors have relevant conflicts of interest to declare.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Partha Pal, Department of Medical Gastroenterology, Asian Institute of Gastroenterology, 6-3-661 Red Rose Cafe Lane, Sangeet Nagar, Somajiguda, Hyderabad 500082, India. partha0123456789@gmail.com
Received: December 10, 2024 Revised: February 26, 2025 Accepted: April 17, 2025 Published online: June 18, 2025 Processing time: 189 Days and 3.7 Hours
Core Tip
Core Tip: Intestinal ultrasound (IUS) is a dynamic, non-invasive imaging tool for Crohn’s disease (CD). It accurately evaluates transmural and extramural complications, with capabilities comparable to magnetic resonance enterography. While these modalities remain necessary for proximal strictures, skip lesions, and extra-intestinal disease, IUS serves as an excellent initial screening option in suspected cases. In established CD, IUS guides clinical decisions during remission, flares, and therapeutic response monitoring. It identifies complications, including strictures and fistulas, with advanced methods like elastography aiding stricture characterization. Additionally, IUS is invaluable in special cases such as perianal fistulas, pregnancy, post-operative CD, and guiding therapeutic interventions.
