Published online Jun 30, 2019. doi: 10.13105/wjma.v7.i6.290
Peer-review started: April 28, 2019
First decision: May 9, 2019
Revised: June 1, 2019
Accepted: June 17, 2019
Article in press: June 17, 2019
Published online: June 30, 2019
Perioperative anaemia in hip fracture is a common problem that can influence clinical outcomes. However, it is uncertain which outcomes will be affected and if anaemia before or after surgery will have different effects.
A better understanding of how perioperative anaemia influences clinical outcomes after hip fracture surgery will help to develop more timely interventions.
To determine the effects of perioperative anaemia during hip fracture surgery on mortality, hospital length of stay, postoperative complications, hospital readmission, change of discharge destination, quality of life and functional status.
Electronic databases will be searched for studies evaluating perioperative anaemia and outcomes of hip fracture surgery. Data on study characteristics, patient demographics, timing of anaemia and clinical outcomes will be extracted. Comparison will be made between participants with anaemia and those without. Data will be pooled for meta-analysis for the primary outcome.
This systematic review seeks to clarify the outcomes associated with perioperative anaemia at various time-points among patients who had hip fracture surgery. An evaluation of the outcomes associated with perioperative anaemia in hip fracture surgery will potentially inform evidence-based clinical practice on the effectiveness and timing of interventions in those with reduced haemoglobin.
In presence of small studies evaluating perioperative anaemia among older people having hip fracture surgery, a systematic review and meta-analysis will provide important directions for future research and clinical practice in this field. This protocol will provide an important methodological foundation for the systematic review.