Systematic Review
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Apr 30, 2019; 7(4): 162-169
Published online Apr 30, 2019. doi: 10.13105/wjma.v7.i4.162
Safety and efficacy of percutaneous transhepatic balloon dilation in removing common bile duct stones: A systematic review
Yu-Liang Li, Dong Li, Bin Liu, Wu-Jie Wang, Wei Wang, Yong-Zheng Wang
Yu-Liang Li, Dong Li, Bin Liu, Wu-Jie Wang, Wei Wang, Yong-Zheng Wang, Department of Interventional Medicine, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China
Author contributions: Li YL initiated the study and secured the funding; Li D and Liu B designed the review and carried out the analysis; Li D drafted the initial manuscript and Li YL and Wang W revised the manuscript; Wang WJ and Wang YZ participated in developing the manuscript; all authors reviewed and approved the final manuscript as submitted.
Supported by the Natural Science Foundation of Shandong Province, Nos. 2014ZRE27479, ZR2018PH032, and ZR2018PH033; and the National Natural Science Foundation of China, No. 6167276.
Conflict-of-interest statement: There are no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yu-Liang Li, MD, PhD, Chief Doctor, Doctor, Professor, Department of Interventional Medicine, The Second Hospital of Shandong University, No. 247, Beiyuan Street, Jinan 250033, Shangdong Province, China. lyl.pro@sdu.edu.cn
Telephone: +86-531-8524777
Received: March 12, 2019
Peer-review started: March 13, 2019
First decision: March 27, 2019
Revised: April 3, 2019
Accepted: April 18, 2019
Article in press: April 18, 2019
Published online: April 30, 2019
ARTICLE HIGHLIGHTS
Research background

Endoscopic sphincterotomy (EST) is widely regarded as the first choice in the management of common bile duct (CBD) stones. However, for some patients, this treatment is not possible.

Research motivation

The percutaneous transhepatic balloon dilation (PTBD) technique has been suggested as an alternative but has yet to gain wide acceptance.

Research objectives

This review was conducted in an effort to clarify the safety and efficacy of the procedure via reviewing cases of PTBD for removing CBD stones. We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Research methods

We searched EMBASE, PubMed, and Web of Science for cases of PTBD that underwent CBD stone removal from 1981 to January 2019. We analyzed all relevant articles available in full text. We extracted data on patient’s age, gender, overall technique success rate, reasons for technique failure, and the presence and type of major and minor complications.

Research results

The overall technique success rate for removing a CBD stone was 98.5% (1327/1347) and 98.1% (109/111) for removing concurrent CBD and gallbladder stones. The total number of failures for eliminating a CBD stone was 20, and the reasons for failure included: Stone impaction (n = 10), intrahepatic bile duct stricture (n = 5), large stone (n = 2), severe CBD dilation (n = 1), multiple stones (n = 1), and duodenal perforation (n = 1).

Research conclusions

Various major complications related to the procedure were reported, but the incidence rate was low (1.4%). No pancreatitis or procedure related mortality was reported. Minor complications including transient hyperamylasemia, nausea, vomiting, abdominal pain, fever, and mild hemobilia were reported. For 218 patients (88 patients with unsuccessful endoscopic removal due to anatomical change and large or impacted stone and 130 cases who refused endoscopic procedure due to poor general condition or other additional disease), the CBD stones were successfully pushed into the duodenum by performing the PTBD procedure.

Research perspectives

PTBD is a safe and effective approach in the nonoperative management of CBD stones. PTBD provides an alternative treatment when endoscopic procedures fail or are unsuitable for the patient.