Yousefi A, Karbalaei M, Keikha M. Extraintestinal infection of Listeria monocytogenes and susceptibility to spontaneous abortion during pregnancy: A systematic review and meta-analysis. World J Meta-Anal 2021; 9(3): 317-326 [DOI: 10.13105/wjma.v9.i3.317]
Corresponding Author of This Article
Masoud Keikha, PhD, Doctor, Instructor, Teaching Assistant, Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Qoreishi Center, Daneshgah Street, Mashhad 1313199137, Iran. masoud.keykha90@gmail.com
Research Domain of This Article
Health Care Sciences & Services
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Meta-Anal. Jun 28, 2021; 9(3): 317-326 Published online Jun 28, 2021. doi: 10.13105/wjma.v9.i3.317
Extraintestinal infection of Listeria monocytogenes and susceptibility to spontaneous abortion during pregnancy: A systematic review and meta-analysis
Amir Yousefi, Mohsen Karbalaei, Masoud Keikha
Amir Yousefi, Masoud Keikha, Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 1313199137, Iran
Mohsen Karbalaei, Department of Microbiology and Virology, School of Medicine, Jiroft University of Medical Sciences, Jiroft 1313199137, Iran
Author contributions: The study was conceived by Keikha M; Keikha M and Karbalaei M analyzed the data; Yousefi A and Karbalaei M wrote the draft; Keikha M provided critical analysis and revision the draft; All authors read and approved the final manuscript.
Conflict-of-interest statement: There is no conflict of interest among the authors.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Masoud Keikha, PhD, Doctor, Instructor, Teaching Assistant, Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Qoreishi Center, Daneshgah Street, Mashhad 1313199137, Iran. masoud.keykha90@gmail.com
Received: April 23, 2021 Peer-review started: April 23, 2021 First decision: June 7, 2021 Revised: June 13, 2021 Accepted: June 16, 2021 Article in press: June 16, 2021 Published online: June 28, 2021
Abstract
BACKGROUND
Listeria monocytogenes (L. monocytogenes) is one of the most important zoonotic bacteria that is transmitted to humans through infected animal products and is the cause of human listeriosis. Pregnant women and immunocompromised patients are more susceptible to the bacterium than healthy people. Recent studies have reported extensive evidence on the role of L. monocytogenes infection and the risk of spontaneous abortion.
AIM
To evaluate the possible connection with L. monocytogenes in the risk of spontaneous abortion in pregnancy.
METHODS
We conducted a systematic literature review using several databases to search the relevant case-control studies on the association between L. monocytogenes infection and spontaneous abortion. Finally, the impact of infection with L. monocytogenes and risk of spontaneous abortion was assessed via odds ratio at corresponding 95% confidence intervals.
RESULTS
In the present study, we evaluated the data of 4059 pregnant women who had a spontaneous abortion, and interestingly their colonization rate of L. monocytogenes was about 20.5%.
CONCLUSION
Therefore, based on statistical analysis, we found that there is a significant relationship between the infection with L. monocytogenes and spontaneous abortion.
Core Tip: Listeria monocytogenes is one of the most common bacterial infections among developing countries. Acquisition of this bacterium during pregnancy is dangerous for the health of neonates. Our results suggested that Listeria monocytogenes can significantly increase the risk of spontaneous abortion during pregnancy.
