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Fryze M, Mlak R, Kulbaka A, Wertheim-Tysarowska K, Matosiuk D, Pietrzak A. Increased risk of anxiety and coping strategies in patients with selected genodermatoses with cornification disruption. Sci Rep 2025; 15:14013. [PMID: 40269104 PMCID: PMC12019405 DOI: 10.1038/s41598-025-98535-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/21/2024] [Accepted: 04/14/2025] [Indexed: 04/25/2025] Open
Abstract
People with genodermatoses face physical pain, social discrimination, and daily life challenges, all of which have an impact on their emotional and psychological well-being. The assessment of anxiety and the development of coping strategies are crucial. This study aimed to compare state and trait anxiety between healthy adults (n = 30) and patients with Mendelian Disorders of cornification (MeDOC) (n = 29). Using the State and Trait Anxiety Inventory and Coping in Stressful Situations Questionnaire, we compared anxiety levels and coping strategies between patients with MeDOC and healthy controls. Given the rarity of MeDOC, the study group is small, but the findings are highly relevant and can significantly improve patients' well-being. Average or high levels of trait anxiety were significantly more common in the study group compared to the control group (25 vs. 18 cases; 86.2% vs. 60%, respectively; p = 0.0488). It was estimated that the risk of average or a high level of trait anxiety was over 4 times higher in the study group than in the control group (OR = 4.2, 95% CI 1.1-15; p = 0.0293). High-level emotion-oriented coping was significantly more frequent in the study group compared to the control group (8 vs. 1 case; 27.6% vs. 3.3%; p = 0.0259), with the risk being 11 times higher in the study group (OR = 11, 95% CI 1.3-95.2; p = 0.0288). No significant correlation was found between demographic, social, educational, clinical factors, and anxiety levels or avoidant-distracted coping. Patients with MeDOC have an increased risk of experiencing anxiety. Understanding the emotions and behaviors of patients with this disease is essential for clinical specialists to guide their coping strategies effectively.
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Affiliation(s)
- Magdalena Fryze
- Department of Psychology, Psychosocial Aspects of Medicine, Medical University of Lublin, Lublin, Poland
| | - Radoslaw Mlak
- Department of Laboratory Diagnostics, Medical University of Lublin, Lublin, Poland
| | | | | | - Dariusz Matosiuk
- Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland
| | - Aldona Pietrzak
- Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Staszica 11, Lublin, 20-080, Poland.
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Alayón AN, Ochoa Arizal N, Noreña Correa M, López Toro J, Hernández Rojas F. Cortisol, cardiovascular risk, and anxiety in full-time workers in Cartagena, Colombia, 2023. Front Psychiatry 2025; 16:1491987. [PMID: 40276070 PMCID: PMC12018309 DOI: 10.3389/fpsyt.2025.1491987] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/11/2024] [Accepted: 03/19/2025] [Indexed: 04/26/2025] Open
Abstract
Background Considering the general trend toward an increased occurrence of cardiovascular and mental health diseases, we studied the relationship between the presence of trait and state anxiety and the alteration of serum cortisol, lipid, and glycemia levels. Material and methods The study assessed 90 full-time workers waist circumferences, as well as their cortisol levels at 8 AM and 4 PM, and their fasting serum glucose and lipid profiles. The construct of trait and state anxiety was assessed by means of the Inventory of Trait-State Anxiety (IDARE Spanish version). Results The state anxiety scale showed high reliability (ω = 0.94, α = 0.939). Moderate to high state anxiety was observed in 61.1% of participants, while 71.1% had moderate to high trait anxiety. Most participants (94.4%) had AM and PM cortisol levels within normal ranges. PM cortisol levels were lower than AM cortisol levels in 95.6% of participants (86/90). Dyslipidemia was present in 60.4% of participants. No significant sex differences were found in AM and PM cortisol or anxiety levels, except for triglycerides, which were higher in men (p = 0.013). State anxiety was positively correlated with PM cortisol levels (r = 0.232, p = 0.028), no significant associations were found with AM cortisol or age. A significant association was observed between waist circumference and fasting glycemia, with 68.9% of participants exceeding the recommended waist circumference threshold. Obesity was significantly associated with hyperglycemia (p = 0.010). An ANOVA revealed a significant effect of state anxiety on evening cortisol levels (F(2, 87) = 7.336, p = 0.001), with the high state anxiety group exhibiting the highest PM cortisol levels. Additionally, a t-test found a significant difference in triglyceride levels between the presence and absence of state anxiety t (87.999) = -2.244, p = 0.027. Conclusions The presence of state anxiety proved to be the type of anxiety most associated with increased evening cortisol levels and triglyceride levels. Understanding the relationships between mental states and biochemical physical conditions will be essential in the future for maximizing the benefits of technological developments applied to the diagnosis, prognosis, and monitoring of patients' overall health.
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Affiliation(s)
- Alicia Norma Alayón
- Biomedical Research Group, Faculty of Health Sciences, Bacteriology Program, Universidad de San Buenaventura, Seccional Cartagena, Cartagena, Colombia
| | - Nohora Ochoa Arizal
- Psychology Research Group, Faculty of Human and Social Sciences, Psychology Program, Universidad de San Buenaventura, Seccional Cartagena, Cartagena, Colombia
| | - Manuel Noreña Correa
- Psychology Research Group, Faculty of Human and Social Sciences, Psychology Program, Universidad de San Buenaventura, Seccional Cartagena, Cartagena, Colombia
| | - Jose López Toro
- Psychology Research Group, Faculty of Human and Social Sciences, Psychology Program, Universidad de San Buenaventura, Seccional Cartagena, Cartagena, Colombia
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Döner S, Efe YS, Elmalı F. Turkish adaptation of the state-trait anxiety inventory short version (STAIS-5, STAIT-5). Int J Nurs Pract 2024:e13304. [PMID: 39323115 DOI: 10.1111/ijn.13304] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/30/2023] [Revised: 07/19/2024] [Accepted: 09/10/2024] [Indexed: 09/27/2024]
Abstract
AIM This study examines the validity and reliability of a Turkish version of the State-Trait Anxiety Inventory Short Version. METHODS The sample consisted of 306 people between the ages of 18-59 who agreed to participate in the study and met the inclusion criteria. Data were collected with the demographic questionnaire, State-Trait Anxiety Inventory Short Version, State-Trait Anxiety Inventory and Brief Fear of Negative Evaluation Scale. RESULTS All factor loadings of the State Anxiety Inventory Short Version were between 0.706 and 0.835, and those of the Trait Anxiety Inventory Short Version were between 0.694 and 0.810. The Cronbach alpha coefficients of the State and Trait Anxiety Inventory Short Version were calculated as 0.838 and 0.837, respectively. There was a significant difference between the first-test and retest values of the State Anxiety Inventory Short Version (p = 0.033) and no difference in the Trait Anxiety Inventory Short Version (p = 0.145). CONCLUSIONS The Turkish-adapted State-Trait Anxiety Inventory Short Version is a valid and reliable measurement tool to determine the anxiety levels of individuals aged 18-59.
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Affiliation(s)
- Seher Döner
- Department of Mental Health and Diseases Nursing, Faculty of Health Sciences, Yozgat Bozok University, Yozgat, Turkey
| | - Yağmur Sezer Efe
- Department of Pediatric Nursing, Faculty of Health Sciences, Erciyes University, Kayseri, Turkey
| | - Ferhan Elmalı
- Faculty of Medicine, Department of Biostatistics, İzmir Katip Çelebi University, İzmir, Turkey
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Mostowik J, Mielimąka M, Rutkowski K, Ostrowski T. Time in the Mental Health Context: Neurotic Symptomatology, Defense Mechanisms and the Perception of Time Perspective Among Patients Diagnosed With Neurotic and Personality Disorders - A Clinical Study. Psychol Rep 2020; 125:232-255. [PMID: 33349168 DOI: 10.1177/0033294120978164] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/17/2022]
Abstract
AIM The main objective of the study is to explore relations between the time perspective, neurotic symptoms, anxiety, and defense mechanisms in the group of patients diagnosed with neurotic and personality disorders (ICD-10 groups: F4x, F60.x and F61) treated with group psychotherapy. The research is conducted on the theoretical basis of the Zimbardo and Boyd's Time Perspective Theory. METHODS The study included 49 patients treated in the day ward for the Treatment of Neurotic Disorders and Behavioral Syndromes at the University Hospital. The measurement of the TP was performed with the Zimbardo Time Perspective Inventory. Patients also completed the State-Trait Anxiety Inventory and the Defense Style Questionnaire 40. The diagnosis was done by licensed psychiatrists and supported with the measures: Symptom Checklist KO"O", Neurotic Personality Questionnaire KON-2006. RESULTS Multiple regression analysis models showed that the four time perspectives (past negative, present fatalistic, present hedonistic, and future) are predicted in different variations by the level of anxiety state or trait and repertoire of used defense mechanisms (immature or mature). CONCLUSIONS Considering the established bilateral correlations, change in the time perspective may constitute an important factor in the reduction of neurotic symptoms, possibly through changes in the repertoire of utilized defense mechanisms. However, there is also possible that altering neurotic symptomatology would alter time perspective. The assessment of the time perspective in patients with neurotic and personality disorders may provide useful data for the diagnosis and the monitoring of psychotherapy effectiveness. Based on the results of this study conducting further research on the role of the changes in the time perspective in the course of psychotherapy is recommended and necessary to expand the understanding of the relations observed in this study.
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Affiliation(s)
- Joanna Mostowik
- Institute of Applied Psychology, Jagiellonian University, Krakow, Poland; Department of Psychotherapy, University Hospital in Krakow, Krakow, Poland
| | | | - Krzysztof Rutkowski
- Department of Psychotherapy, Jagiellonian University Medical College, Krakow, Poland
| | - Tadeusz Ostrowski
- Faculty of Psychology and Humanities, Andrzej Frycz-Modrzewski Cracow University, Krakow, Poland
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Panek MG, Karbownik MS, Kuna PB. Comparative analysis of clinical, physiological, temperamental and personality characteristics of elderly subjects and young subjects with asthma. PLoS One 2020; 15:e0241750. [PMID: 33156872 PMCID: PMC7647458 DOI: 10.1371/journal.pone.0241750] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [MESH Headings] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/06/2020] [Accepted: 10/21/2020] [Indexed: 11/18/2022] Open
Abstract
BACKGROUND Asthma is a heterogeneous disease of a complex etiology in which genetic, environmental and personality variables are important factors determining the development of complicated strategies related to coping with stress and temperament traits. Our thesis is that coping styles in asthmatic patients are modified by the environment (chronic inflammation and stress) which affects individual temperament traits in the course of time. Thus, patient age is one of factors which determine the clinical image of asthma and its natural history. AIM The aim of the study was to evaluate the variables describing stress coping styles and temperament in young (18 to 35 years old) and elderly asthmatics (aged ≥60 years). MATERIAL AND METHODS A total of 200 patients, 104 elderly and 96 young asthmatics were enrolled in the study. Apart from medical examination, the following tests were performed in all subjects: the Formal Characteristics of Behavior- Temperament Inventory (FCB-TI), Coping Inventory for Stressful Situations (CISS), Beck Depression Inventory, State-Trait Anxiety Inventory, and Borg Rating of Perceived Exertion (RPE) Scale. RESULTS Elderly patients with asthma exhibited higher intensity of anxiety as a trait, a higher level of depression and experienced dyspnea, as well as higher levels of stress coping strategies such as Avoidance-Oriented Coping (AOC), Distraction Seeking (DS) and Social Diversion (SD) compared to young asthmatics. In elderly patients, Perseverance and Sensory Sensitivity traits have been observed to decline with the duration and development of asthma at later life stages as opposed to young asthmatics, in whom these temperament characteristics are elevated. CONCLUSIONS Asthma is a heterogeneous disease of a complex etiopathogenesis that has a complex interplay with mental health. The present study confirms a relationship between age and stress coping strategies as well as temperament traits.
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Affiliation(s)
- Michał G. Panek
- Medical University of Lodz, Department of Internal Medicine, Asthma and Allergy of the Medical University of Lodz, Lodz, Poland
- * E-mail:
| | - Michał S. Karbownik
- Medical University of Lodz, Department of Pharmacology and Toxicology of the Medical University of Lodz, Lodz, Poland
| | - Piotr B. Kuna
- Medical University of Lodz, Department of Internal Medicine, Asthma and Allergy of the Medical University of Lodz, Lodz, Poland
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Wang S, Gao JY, Li X, Wu Y, Huo XX, Han CX, Kang MJ, Sun H, Ge BL, Liu Y, Liu YQ, Zhou JP, Wang Z. Correlation between crowdedness in emergency departments and anxiety in Chinese patients. World J Clin Cases 2020; 8:2802-2816. [PMID: 32742990 PMCID: PMC7360700 DOI: 10.12998/wjcc.v8.i13.2802] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/17/2020] [Revised: 05/13/2020] [Accepted: 06/02/2020] [Indexed: 02/05/2023] Open
Abstract
BACKGROUND Emergency department (ED) overcrowding is a severe health care concern, while anxiety and depression rates among ED patients have been reported to be substantially higher compared to the general population. We hypothesized that anxiety due to over crowdedness may lead to adverse events in EDs.
AIM To investigate correlations between crowdedness in EDs and anxiety of patients and nurses, and to identify factors affecting their anxiety.
METHODS In this prospective observational study, a total 43 nurses and 389 emergency patients from two tier III hospitals located in Beijing were included from January 2016 to August 2017. Patients were grouped into inpatients when they were hospitalized after diagnoses, or into outpatients when they were discharged after treatments. The State Trait Anxiety Inventory (STAI Form Y) questionnaire was used to investigate patient and nurse anxieties, while crowdedness of EDs was evaluated with the National Emergency Department Over Crowding Score.
RESULTS The present results revealed that state anxiety scores (49.50 ± 6.00 vs 50.80 ± 2.80, P = 0.005) and trait anxiety scores (45.40 ± 5.70 vs 46.80 ± 2.70, P = 0.002) between inpatients (n = 173) and outpatients (n = 216) were significantly different, while the state anxiety of nurses (44.70 ± 5.80) was different from those of both patient groups. Generalized linear regression analysis demonstrated that multiple factors, including crowdedness in the ED, were associated with state and trait anxieties for both inpatients and outpatients. In addition, there was an interaction between state anxiety and trait anxieties. However, multivariable regression analysis showed that while overcrowding in the ED did not directly correlate with patients’ and nurses’ anxiety levels, the factors that did correlate with state and trait anxieties of inpatients were related to crowdedness. These factors included waiting time in the ED, the number of patients treated, and the number of nurses in the ED, whereas for nurses, only state and trait anxieties correlated significantly with each other.
CONCLUSION Waiting time, the number of patients treated, and the number of nurses present in the ED correlate with patient anxiety in EDs, but crowdedness has no effect on nurse or patient anxiety.
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Affiliation(s)
- Shuang Wang
- Department of Emergency Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
| | - Jun-Yi Gao
- Department of Cardiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
| | - Xiang Li
- Emergency Intensive Care Unit, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
| | - Yu Wu
- Department of Orthopedic Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
| | - Xiao-Xia Huo
- Department of Emergency Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
| | - Chao-Xia Han
- Department of Emergency Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
| | - Meng-Jie Kang
- Emergency Intensive Care Unit, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
| | - Hong Sun
- Department of Emergency Medicine, Peking University People’s Hospital, Beijing 100044, China
| | - Bao-Lan Ge
- Department of Emergency Medicine, Peking University Third Hospital, Beijing 100191, China
| | - Yu Liu
- Department of Emergency Medicine, Chinese PLA General Hospital, Beijing 100853, China
| | - Ying-Qing Liu
- Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
| | - Jian-Ping Zhou
- Department of Emergency Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
| | - Zhen Wang
- Department of Emergency Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
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