• Case report
• Child
• Infection
• Spleen
• Splenectomy
• Tuberculosis

• causes of splenic abscess
• diagnosis of splenic abscess
• management of splenic abscess
• sign and symptoms of splenic abscess
• splenic abscess

• Humans
• Magnetic Resonance Imaging/methods
• Tomography, X-Ray Computed/methods
• Diagnosis, Differential
• Splenic Diseases/diagnostic imaging
• Splenic Diseases/pathology
• Incidental Findings
• Spleen/diagnostic imaging
• Spleen/pathology
• Splenic Neoplasms/diagnostic imaging
• Splenic Neoplasms/pathology
• Splenectomy

• CT
• MRI
• benign
• solitary
• spleen

Solitary splenic tuberculosis (TB) is unusual and rarely reported. Whether splenic TB is best treated surgically is still controversial. We describe a 73-year-old man with solitary splenic TB and no extrapulmonary TB.

We report the case of a 73-year-old man with solitary splenic TB who complained of emaciation and fatigue. Abdominal computed tomography (CT) images suggested a splenic space-occupying lesion. We then performed a CT-guided splenic biopsy. The postoperative pathological examination revealed splenic TB. The patient took quadruple anti-TB medication. After 1 year, the patient recovered his normal weight and had no feeling of fatigue, and the splenic lesion had shrunk significantly.

If patients receive combined, appropriate, regular, full-time anti-TB treatment, solitary splenic TB may be cured.

• Infectious diseases
• Solitary splenic tuberculosis
• Computed tomography
• Computed tomography-guided spleen biopsy
• Anti-tuberculosis medicine
• Pathological diagnosis
• Case report

• Alemtuzumab/adverse effects
• Antibodies, Monoclonal
• Antibodies, Monoclonal, Humanized/therapeutic use
• Humans
• Lymphoma, T-Cell, Peripheral/diagnosis
• Lymphoma, T-Cell, Peripheral/drug therapy
• Lymphoma, T-Cell, Peripheral/pathology

•

In areas where tuberculosis is prevalent, a splenic tuberculosis should be considered in the differential diagnosis of patients presenting with fever of unknown origin and splenomegaly.

• Case report
• Covid-19
• Pyopneumothorax
• Splenic
• Tuberculosis

We present a case of pancreatic and splenic tuberculosis (TB) in a 15-year-old human immunodeficiency virus-negative patient who was initially misdiagnosed as suffering from a pancreatic carcinoma with splenic metastases. Pancreatic and splenic TB are extremely rare in young immunocompetent patients, with a nonspecific clinical presentation, making the diagnosis elusive.

The spleen plays an important role in the immunological homeostasis of the body. Several neoplastic and non-neoplastic diseases may affect this organ, and imaging is of fundamental importance for diagnosis. Infectious diseases of the spleen can be encountered in daily radiology practice, and differential diagnosis may sometimes be challenging. Infectious involvement of the spleen can be primary or secondary to a different source outside the spleen. Despite the fact that different infectious diseases may cause similar imaging findings, we believe that differential diagnosis between different causes may also be possible in certain patients with imaging. Early diagnosis may potentially enhance patients’ treatment and outcome. In this review, we aimed to increase imaging specialists’ awareness of splenic infections by describing the multimodality imaging features of common and atypical infections of the spleen with their differential diagnoses.

• Cross-sectional
• Differential diagnosis
• Spleen
• İmaging
• İnfection

• Diagnosis, Differential
• Humans
• Multimodal Imaging
• Radiography
• Splenic Diseases/diagnostic imaging

The aim of this study was to characterize the contrast-enhanced ultrasound imaging features of focal splenic tuberculosis.

We retrospectively analyzed the conventional ultrasound (US) and contrast-enhanced ultrasound (CEUS) imaging features of 22 patients with splenic TB confirmed by surgical histopathology or biopsy.

Conventional US demonstrated that 15 of the 22 patients had a single lesion, while 7 had multiple lesions. The maximum diameter of the lesions ranged from 1.0 to 3.7 cm. Of the 22, 17 were detected with hypoecho and 5 were detected with complex echo by conventional US. Seven (7/22) were detected with blood flow signals by color Doppler flow image (CDFI). CUES demonstrated that 18 cases (81.8%, 18/22) began to enhance in the arterial phase, mostly followed by slow wash-out in the intermediate or late parenchymal phase, and 4 (18.2%, 4/22) presented with non-enhancement during all phases. The enhancement patterns were categorized into 4 types: Type I, homogeneous enhancement (2/22); Type II, rim-like enhancement (12/22); Type III, septation-like enhancement (4/22); and Type IV, non-enhancement (4/22).

CEUS showed that splenic TB lesions were enhanced in the arterial phase, followed by slow washed out or persistent enhancement in the intermediate and late parenchymal phases. The rim- or septation-like enhancement may be helpful for diagnosing splenic TB. The splenic lesions presenting round hypoecho by conventional US and complete non-enhancement by CEUS are highly suspicious of splenic TB.

Tuberculosis (TB), as a major public health concern, is affecting almost 10 million people globally. At present, diagnostic and screening efforts mainly focus on positive smear results. Therefore, the number of extra pulmonary and negative sputum TB is rising and hampering the diagnosis and treatment process due to the large number of false negatives. Rare cases such as solitary splenic TB are usually seen in patients with splenic abnormalities, spleen trauma, immunosuppression, sickle cell disease, pyogenic infections, etc.

A 40-year-old female with no comorbidity came with chief complaint of early satiety every mealtime and epigastric pain in the last 6 months prior to admission. There was no significant positive examination except for positive IGRA test and enlargement of spleen with multiple cystic lesions on abdominal CT. We performed laparotomy with splenectomy followed by a histopathology examination which showed features of primary tubercular abscess.

In the immunocompromised patient, the visceral abdomen is usually involved and a part of miliary TB. However, this case revealed the rare possibility of a healthy person with primary isolated tubercular splenic abscess while being immunocompetent and lacking any comorbidity.

Splenic TB diagnosis is difficult in patients lacking pulmonary involvement and without specific symptoms. Thorough examinations and clinical expertise are needed to provide accurate diagnosis and treat uncommon forms of TB and cases with negative smear results in consideration of rising prevalence and difficult disease control.

•

A case of isolated splenic tuberculosis was found in an immunocompetent patient.

• Case report
• Immunocompetent
• Infection
• Spleen
• Tuberculosis

• disseminated tuberculosis
• miliary
• splenic tuberculosis
• tuberculosis

• child
• immunocompetent
• spleen
• splenic abscess
• tuberculosis