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Luo C, Li L, Hou L, Shi F. Effects of tiered cardiac rehabilitation on CRP, TNF-α, and physical endurance in older adults with coronary heart disease. Open Life Sci 2025; 20:20221040. [PMID: 40417004 PMCID: PMC12103183 DOI: 10.1515/biol-2022-1040] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/30/2024] [Revised: 11/21/2024] [Accepted: 12/11/2024] [Indexed: 05/27/2025] Open
Abstract
Coronary heart disease (CHD) is a highly prevalent disease in the elderly population, with atherosclerosis as its pathology, which can also be viewed as a chronic inflammatory response of the organism. Regular moderate-intensity exercise can direct the immune response toward an anti-inflammatory state, which is beneficial for improving the health and exercise tolerance. In cardiac rehabilitation, attention to the management of inflammatory factors as well as the improvement of exercise endurance is beneficial for the rehabilitation of elderly patients with coronary artery disease. This study investigates the impact of tiered cardiac rehabilitation programs on levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), and the capacity for physical exertion in older CHD patients. From March 2020 to April 2022, 94 elderly patients with CHD visiting our institution were recruited and randomly allocated into either a control group or an observation group, each comprising 47 participants. The standard care group participated in traditional rehabilitation exercises, whereas the experimental group received customized, tiered, cardiac rehabilitation interventions. We assessed the variations in CRP and tumor necrosis factor alpha (TNF-α) levels, along with exercise capacity, before and after treatment in both groups. The result shows that significant reductions in CRP and TNF-α levels were seen in the experimental group after 4 and 12 weeks, compared to the standard care group. Analysis showed clear trends in CRP and TNF-α changes over the interventions, with the experimental group showing better results. CRP levels decreased consistently, while TNF-α levels stayed stable. The experimental group also showed improvements in physical endurance measures compared to the control group. Interleukin 6 (IL-6) and fibrinogen (Fib) in the observation group decreased compared with the control group (P < 0.01). After 12 weeks of treatment, CRP and TNF-α showed significant negative correlation with exercise endurance index - 6 min walking test (6 MWT), anaerobic threshold (AT), maximum oxygen consumption (VO2max), and exercise duration (ED); significant positive correlation between cardiac rehabilitation grade and exercise endurance index (6 MWT, AT, VO2max and ED); and both groups experienced cardiovascular adverse events and exercise muscle injury. The analysis shows that the graded nursing of cardiac rehabilitation can effectively reduce the levels of CRP, TNF-α, IL-6, and Fib in elderly patients with CHD and significantly improve the exercise endurance of patients with good safety.
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Affiliation(s)
- Cong Luo
- Department of Cardiovascular Medicine, The Fourth Hospital of Changsha, Changsha, 410219, China
| | - Lan Li
- Ward of Neurology, The Fourth Hospital of Changsha, Changsha, 410006, China
| | - Lan Hou
- Department of Cardiovascular Medicine, The Fourth Hospital of Changsha, Changsha, 410219, China
| | - Fengjiao Shi
- Department of Cardiovascular Medicine, The Fourth Hospital of Changsha, Changsha, 410219, China
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Szlacheta P, Wlazło M, Grajek M, Kłoda-Suchoń M, Choromańska-Matera B, Yanakieva A, Korzonek-Szlacheta I. Perception of Social Support and Disease Acceptance Among Patients Undergoing Cardiac Rehabilitation-Cross-Sectional Study. Healthcare (Basel) 2025; 13:1059. [PMID: 40361837 PMCID: PMC12071769 DOI: 10.3390/healthcare13091059] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/10/2025] [Revised: 04/30/2025] [Accepted: 05/03/2025] [Indexed: 05/15/2025] Open
Abstract
BACKGROUND Cardiovascular diseases (CVD), the leading cause of mortality worldwide, require a multidisciplinary approach, with cardiac rehabilitation being a recommended component. The rehabilitation process may be directly influenced by social support, which enhances motivation to cope with the disease and fosters its acceptance. AIMS This study aims to assess the level of social support among patients undergoing cardiac rehabilitation and its impact on disease acceptance. METHODS The study included a sample of 150 patients currently participating in cardiac rehabilitation. Data were collected through direct contact using the validated, anonymous Acceptance of Illness Scale questionnaire, supplemented with a demographic section addressing social support. RESULTS The majority of respondents reported receiving strong family support (51.3%) and good institutional support (47.3%) during treatment. The mean score for illness acceptance was 29.6 ± 6.9, indicating a high acceptance level observed in most patients (57.3%). The p-values for the association between illness acceptance and support from family and institutions were p = 0.43 and p = 0.82, respectively, suggesting no statistically significant relationship. CONCLUSIONS Patients undergoing cardiac rehabilitation generally experience strong family support, good institutional support, and a high level of disease acceptance. No statistically significant relationship was observed between family or institutional support and the level of disease acceptance.
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Affiliation(s)
- Patryk Szlacheta
- Department of Basic Medical Sciences, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, 41902 Bytom, Poland
| | - Marika Wlazło
- Department of Cardiovascular Disease Prevention, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, 41902 Bytom, Poland; (M.W.); (I.K.-S.)
| | - Mateusz Grajek
- Department of Public Health, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, 41902 Bytom, Poland;
| | - Magdalena Kłoda-Suchoń
- Silesian Center for Rehabilitation and Prevention, 43450 Ustroń, Poland; (M.K.-S.); (B.C.-M.)
| | | | - Antoniya Yanakieva
- Department of Health Technology Assessment, Faculty of Public Health, Medical University of Sofia, 1000 Sofia, Bulgaria;
| | - Ilona Korzonek-Szlacheta
- Department of Cardiovascular Disease Prevention, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, 41902 Bytom, Poland; (M.W.); (I.K.-S.)
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Farris SG, Kibbey MM, Derby L, Keller B, Leyro TM, Alderman BL, Steinberg MB, Abrantes AM, DiBello AM. A Confirmatory Factory Analysis of the Exercise Sensitivity Questionnaire (ESQ). J Cardiopulm Rehabil Prev 2025; 45:207-214. [PMID: 40014001 DOI: 10.1097/hcr.0000000000000933] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/28/2025]
Abstract
PURPOSE The Exercise Sensitivity Questionnaire (ESQ) is a self-report measure used to assess the extent to which different physical sensations of exercise elicit anxiety (ie, exercise sensitivity). The ESQ was developed for individuals with cardiovascular conditions and initially validated in a non-clinical sample. This study evaluates the factor structure and measurement invariance in a clinical sample of adults with various cardiovascular conditions. METHODS This was a cross-sectional study with retrospective chart review. Patients (N = 265; 73% male, mean age 67.8 ± 10.5 years) were attending an orientation for outpatient medically supervised exercise-based cardiac rehabilitation. The factor structure was examined using Confirmatory Factor Analysis, and tests of measurement invariance were evaluated by sex and advanced age (<65 years, >65 years). Internal consistency, descriptive characteristics, and correlates of ESQ scores and its factors were evaluated. Concurrent validity was evaluated in a subset of patients (N = 57) with elevated exercise sensitivity. RESULTS The Confirmatory Factor Analysis supported a 2-factor model, which was invariant, but not a 1-factor model, and reflected anxiety about (1) cardiopulmonary and (2) pain/weakness exercise sensations. Internal consistency of ESQ items was high. ESQ scores were associated with higher body mass index and shorter 6-Minute Walk Test distance, particularly the pain/weakness factor. ESQ scores evidenced preliminary concurrent validity with anxiety sensitivity and general anxiety but discriminant validity with depressive symptoms. CONCLUSIONS There is support for the validity and reliability of ESQ scores as a 2-dimensional index of exercise sensitivity. The ESQ taps a psychological phenotype with relevance to exercise tolerance, and potentially cardiac rehabilitation participation, that warrants continued investigation.
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Affiliation(s)
- Samantha G Farris
- Author Affiliations: Department of Psychology (Dr Farris., Ms Kibbey, Ms. Derby, Ms Keller and Dr Leyro), Department of Kinesiology & Health (Dr Alderman), Department of Applied Psychology, Graduate School of Applied and Professional Psychology (Dr DiBello), Rutgers, the State University of New Jersey, New Brunswick, New Jersey; Department of Medicine (Dr Steinberg), Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey; Butler Hospital, Behavioral Medicine and Addiction Research Unit (Dr Abrantes), Providence, Rhode Island; and Department of Psychiatry and Human Behavior (Dr Abrantes), Alpert Medical School at Brown University, Providence, Rhode Island
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Nesbitt K, Champion S, Pearson V, Gebremichael LG, Dafny H, Ramos JS, Suebkinorn O, Pinero de Plaza MA, Gulyani A, Du H, Clark RA, Beleigoli A. The effectiveness of interactive cardiac rehabilitation web applications versus usual care on programme completion in patients with cardiovascular disease: A systematic review and meta-analysis of randomised controlled trials. J Telemed Telecare 2025; 31:475-486. [PMID: 37769293 DOI: 10.1177/1357633x231201874] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 09/30/2023]
Abstract
IntroductionAlthough available evidence demonstrates positive clinical outcomes for patients attending and completing cardiac rehabilitation, the effectiveness of interactive cardiac rehabilitation web applications on programme completion has not been systematically examined.MethodsThis JBI systematic review of effects included studies measuring effectiveness of interactive cardiac rehabilitation web applications compared to telephone, and centre-based programmes. Outcome data were pooled under programme completion and clinical outcomes (body mass index, low-density lipoproteins, and blood pressure). Databases including MEDLINE (via Ovid), Cochrane Library, Scopus (via Elsevier) and CINAHL (via EBSCO) published in English were searched. Articles were screened and reviewed by two independent reviewers for inclusion, and the JBI critical appraisal tool and Grading of Recommendations Assessment, Development and Evaluation tool were applied to appraise and assess the certainty of the findings of the included studies. A meta-analysis of the primary and secondary outcomes used random effects models.ResultsIn total, nine studies involving 1175 participants who participated in web-based cardiac rehabilitation to usual care were identified. The mean critical appraisal tool score was 76 (standard deviation: 9.7) with all (100%) studies scoring >69%, and the certainty of evidence low. Web-based programmes were 43% more likely to be completed than usual care (risk ratio: 1.43; 95% confidence interval: 0.96, 2.13) There was no difference between groups for clinical outcomes.DiscussionDespite the relatively small number of studies, high heterogeneity and the limited outcome measures, the results appeared to favour web-based cardiac rehabilitation with regard to programme completion.
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Affiliation(s)
- Katie Nesbitt
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
- Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia
| | - Stephanie Champion
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
- Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia
| | - Vincent Pearson
- JBI Transfer Science Division, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia
| | - Lemlem G Gebremichael
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
- Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia
| | - Hila Dafny
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
- Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia
| | - Joyce S Ramos
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
| | - Orathai Suebkinorn
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
| | - Maria A Pinero de Plaza
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
- Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia
- National Health and Medical Research Council, Transdisciplinary Centre of Research Excellence in Frailty and Healthy Ageing, Adelaide, SA, Australia
| | - Aarti Gulyani
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
| | - Huiyun Du
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
| | - Robyn A Clark
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
- Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia
| | - Alline Beleigoli
- Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, Australia
- Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia
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Hamilton DE, Xie JX, Chang AL, Beatty AL, Golbus JR. Digital Technologies and Artificial Intelligence in Cardiac Rehabilitation: A Narrative Review. J Cardiopulm Rehabil Prev 2025; 45:169-180. [PMID: 40162809 DOI: 10.1097/hcr.0000000000000935] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 04/02/2025]
Abstract
PURPOSE This review explores the role and impact of digital technology in cardiac rehabilitation (CR), assessing its potential to enhance patient outcomes and address barriers to CR delivery. REVIEW METHODS A comprehensive literature search was conducted using curated search terms to target CR studies using digital technologies as an adjunct to in-person CR or as part of remote (ie, asynchronous) or virtual (ie, synchronous audiovisual communication) formats. The literature search focused on studies that evaluated the implementation and efficacy of using digital technologies within CR. SUMMARY Digital technology offers significant opportunities to improve CR by providing flexible and scalable solutions that can overcome traditional barriers to CR such as accessibility and capacity constraints. Remote or virtual CR delivery that incorporates digital technologies improves CR adherence and achieves similar improvements in exercise capacity when compared to in-person CR. While the majority of studies have focused on exercise, digital technologies are increasingly used to deliver comprehensive CR solutions as part of remote and virtual CR programs. However, challenges and gaps in the literature remain, such as the impact of digital literacy and promoting equitable CR access, particularly in high-risk and vulnerable populations. Further research needs to focus on longer term outcomes to evaluate the safety, efficacy, and cost-effectiveness of digital CR interventions. The potential of digital health to transform CR and reduce the burden of cardiovascular disease is substantial and warrants further investigation.
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Affiliation(s)
- David E Hamilton
- Author Affiliations: Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan (Drs Hamilton, Xie, and Golbus); Division of Cardiovascular Medicine, Department of Internal Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania (Dr Chang); Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan (Dr Chang); Department of Epidemiology and Biostatistics, University of California, San Francisco, California (Dr Beatty); Division of Cardiology, Department of Medicine, University of California, San Francisco, California (Dr Beatty); and Michigan Integrated Center for Health Analytics and Medical Prediction (MiCHAMP), University of Michigan, Ann Arbor, Michigan (Dr Golbus)
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Nasrawi D, Latimer S, Massey D, Gillespie BM. Postoperative care pathways for patients following coronary artery bypass grafting surgery: An observational study. Aust Crit Care 2025; 38:101234. [PMID: 40286512 DOI: 10.1016/j.aucc.2025.101234] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/17/2024] [Revised: 01/28/2025] [Accepted: 03/11/2025] [Indexed: 04/29/2025] Open
Abstract
AIMS The aim of this study was to describe the postoperative care pathway, with phase 1 cardiac rehabilitation (CR) delivery, for adult patients following coronary artery bypass grafting (CABG) surgery at one large hospital in Queensland, Australia. DESIGN AND METHODS This observational study involved structured observations, patient electronic medical record audits, and field notes to gather postoperative data. Four continuous hours of patient and healthcare professional (HCP) observations gathered at 30-min intervals occurred on 12 separate days over a 1-month period (February-March 2023). We observed post-CABG patients and HCPs involved in delivering direct care. Data were gathered on the clinical care, timing, delivery mode, and education content. RESULTS Ten post-CABG patients and nine HCPs were observed. Postoperative care delivered by HCPs focussed on clinical care tasks and patient education activities. Patients participated in education focussed on respiratory exercises, wound care, anticoagulant therapy, and thromboembolic deterrent education. HCPs discussed pain management with two patients. CONCLUSION Education was the primary strategy delivered by HCPs to CABG patients during the postoperative care pathway and phase 1 CR; however, many patients were overwhelmed by the complicated information they received. Opportunities exist to improve the postoperative care pathway with phase 1 CR delivery by developing patient-centred education interventions.
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Affiliation(s)
- Dima Nasrawi
- School of Nursing and Midwifery, Griffith University, Logan Campus Meadowbrook QLD, Australia; School of Health and Human Sciences, Southern Cross University, Gold Coast Airport, Terminal Dr, Bilinga QLD 4225, Australia.
| | - Sharon Latimer
- School of Nursing and Midwifery, NHMRC Centre of Research Excellence in Wiser Wounds Care, Griffith University, Gold Coast Campus Southport QLD, Australia.
| | - Debbie Massey
- School of Nursing and Midwifery, Edith Cowan University, Joondalup Drive, Joondalup, WA 6027, Australia.
| | - Brigid M Gillespie
- School of Nursing and Midwifery, NHMRC Centre of Research Excellence in Wiser Wounds Care, Griffith University, Gold Coast Campus Southport QLD, Australia.
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Conradson HE, Chirico D, King-Shier K, Rouleau C, Campbell TS, Aggarwal S, Arena R, Hauer T, Wilton SB, Williamson TM. Women's Improvements in Cardiorespiratory Fitness Following Cardiac Rehabilitation Differ by Body Mass Index Category. CJC Open 2025; 7:525-534. [PMID: 40433134 PMCID: PMC12105753 DOI: 10.1016/j.cjco.2024.12.007] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/16/2024] [Accepted: 12/10/2024] [Indexed: 05/29/2025] Open
Abstract
Background Improving women's cardiovascular outcomes requires optimizing cardiorespiratory fitness (CRF), as higher CRF predicts improved mortality in people with cardiovascular disease (CVD). As such, increasing CRF is a key goal of cardiac rehabilitation (CR). This study assesses the potential influence of body habitus, assessed by body mass index (BMI), on improvements in CRF in women with CVD. Methods Women (18+ years) diagnosed with CVD who completed a 12-week exercise-based CR program between 1996 and 2016 were included in this retrospective analysis. Women completed a symptom-limited graded exercise test before CR and at CR completion to determine CRF via peak metabolic equivalents (METs). Women were categorized by baseline BMI: normal = 18.5 to 24.9 kg/m2, overweight = 25.0 to 29.9 kg/m2, and obese ≥ 30 kg/m2. Mixed analysis of covariance (ANCOVA) was performed to evaluate the impact of BMI classification on ΔMETs at 12 weeks. Results Data from 1313 women (mean age = 62 ± 11 years) were analyzed. Results from mixed ANCOVA indicated a significant time (pre-CR, 12 weeks) by BMI category interaction (F [2,1307] = 3.20, P = 0.041, ƞp2 = 0.005). Follow-up analyses of variance (ANOVAs) showed significant improvements in ΔMETs in women with normal and overweight BMI categories (standard mean difference =1.03, n = 454 and 0.92, n = 461, respectively, P < 0.001). However, ΔMETs among women classified as obese was nonsignificant using a Bonferroni-adjusted alpha of 0.017 (standardized mean difference [SMD] = 0.79, P = 0.028; n = 398). Conclusions A 12-week exercise-based CR program increased CRF in women classified as normal or overweight by BMI, whereas those with obesity did not realize similar improvements. Women with obesity may need tailored strategies to increase their improvements in CRF in CR. Clinical Trial Registration REB18-0083.
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Affiliation(s)
| | - Daniele Chirico
- Faculty of Kinesiology, University of Calgary and TotalCardiology Research Network, Calgary, Alberta, Canada
| | - Kathryn King-Shier
- Faculty of Nursing and Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
| | - Codie Rouleau
- Department of Psychology, University of Calgary and TotalCardiology, Research Network, Calgary, Alberta, Canada
| | - Tavis S. Campbell
- Department of Psychology, University of Calgary and TotalCardiology Research Network, Calgary, Alberta, Canada
| | - Sandeep Aggarwal
- Departments of Cardiac Sciences and Community Health Sciences, University of Calgary and TotalCardiology Research Network, Calgary, Alberta, Canada
| | - Ross Arena
- Department of Physical Therapy, University of Illinois Chicago, Chicago, Illinois, USA and TotalCardiology Research Network, Calgary, Alberta, Canada
| | - Trina Hauer
- Clinical Operations, TotalCardiology Research Network, Calgary Alberta, Canada
| | - Stephen B. Wilton
- Departments of Cardiac Sciences and Community Health Sciences, University of Calgary and TotalCardiology Research Network, Calgary, Alberta, Canada
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Li L, Ringeval M, Wagner G, Paré G, Ozemek C, Kitsiou S. Effectiveness of home-based cardiac rehabilitation interventions delivered via mHealth technologies: a systematic review and meta-analysis. Lancet Digit Health 2025; 7:e238-e254. [PMID: 40023729 DOI: 10.1016/j.landig.2025.01.011] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/08/2024] [Revised: 01/09/2025] [Accepted: 01/16/2025] [Indexed: 03/04/2025]
Abstract
BACKGROUND Centre-based cardiac rehabilitation (CBCR) is underused due to low referral rates, accessibility barriers, and socioeconomic constraints. mHealth technologies have the potential to address some of these challenges through remote delivery of home-based cardiac rehabilitation (HBCR). This study aims to assess the effects of mHealth HBCR interventions compared with usual care and CBCR in patients with heart disease. METHODS We conducted a systematic review and meta-analysis of randomised controlled trials of mHealth HBCR interventions. Four electronic databases (MEDLINE, CENTRAL, CINAHL, and Embase) were searched from inception to March 31, 2023, with no restrictions on language or publication type. Eligible studies were randomised controlled trials of adult patients (age ≥18 years) with heart disease, comparing mHealth interventions with usual care or CBCR. The primary outcome of interest was aerobic exercise capacity, assessed with VO2 peak or 6-min walk test (6MWT). Quality of evidence was assessed using the GRADE system. This review was registered with PROSPERO, CRD42024544087. FINDINGS Our search yielded 9164 references, of which 135 were retained for full-text review. 13 randomised controlled trials met eligibility criteria and were included in the systematic review, involving 1508 adults with myocardial infarction, angina pectoris, or heart failure, or who had undergone revascularisation. Intervention duration ranged from 6 weeks to 24 weeks. Random-effects meta-analysis showed that, compared with usual care, mHealth HBCR significantly improved 6MWT (mean difference 24·74, 95% CI 9·88-39·60; 532 patients) and VO2 peak (1·77, 1·19-2·35; 359 patients). No significant differences were found between mHealth HBCR and CBCR. Quality of evidence ranged from low to very low across outcomes due to risk of bias and imprecision (small sample size). INTERPRETATION mHealth HBCR could improve access and health outcomes in patients who are unable to attend CBCR. Further research is needed to build a robust evidence base on the clinical effectiveness and cost-effectiveness of mHealth HBCR, particularly in comparison with CBCR, to inform clinical practice and policy. FUNDING None.
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Affiliation(s)
- Leah Li
- Department of Biomedical and Health Information Sciences, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA
| | - Mickaël Ringeval
- Department of Information Technologies, HEC Montréal, Montréal, QC, Canada
| | - Gerit Wagner
- Faculty of Information Systems and Applied Computer Science, Otto-Friedrich-Universität Bamberg, Bamberg, Germany
| | - Guy Paré
- Department of Information Technologies, HEC Montréal, Montréal, QC, Canada
| | - Cemal Ozemek
- Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA
| | - Spyros Kitsiou
- Department of Biomedical and Health Information Sciences, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
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Bomtempo APD, Ghisi GLDM. Exploring Cardiac Rehabilitation Barriers Across Health Literacy Levels. Health Lit Res Pract 2025; 9:e72-e77. [PMID: 40489385 DOI: 10.3928/24748307-20241127-02] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 06/11/2025] Open
Abstract
This study aimed to explore the barriers to cardiac rehabilitation (CR) participation across individuals with different levels of health literacy. A cross-sectional study was conducted among individuals referred to a CR program. Participants completed online surveys assessing CR barriers using the Cardiac Rehabilitation Barriers Scale and health literacy using the Brief Health Literacy Screening Tool. Descriptive statistics and comparisons were performed. Among 881 individuals invited, 400 responded, with varying levels of health literacy: 22(6%) limited, 305(76%) marginal, and 72(18%) adequate. The greatest barriers included family responsibilities, lack of energy, and a preference for managing health alone. However, distinct patterns emerged based on health literacy levels, with individuals citing different barriers. Although no significant differences were observed in CR barriers based on health literacy, understanding individual-specific challenges is crucial for intervention development. Addressing common barriers such as family responsibilities and logistical challenges could enhance CR engagement and adherence. [HLRP: Health Literacy Research and Practice. 2025;9(2):e72-e77.].
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Vindis K, Nemeth N, Marge C, Pantis C, Pop MG, Pop MS, Bondar LI, Jurcau MC, Babeș K. Effects of Physical Exercise on Walking Distance and Functional Limitations in Patients with Chronic Dyspnea. MEDICINA (KAUNAS, LITHUANIA) 2025; 61:636. [PMID: 40282927 PMCID: PMC12028406 DOI: 10.3390/medicina61040636] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 02/28/2025] [Revised: 03/23/2025] [Accepted: 03/27/2025] [Indexed: 04/29/2025]
Abstract
Background and Objectives: Chronic dyspnea is a common clinical manifestation in patients suffering from cardiovascular and respiratory diseases globally, representing an independent predictor of mortality for these patients. In addition, it may be a symptom associated with other conditions such as anemia, physical deconditioning, or anxiety. Methods: A prospective study was conducted, between 1 January 2021 and 30 June 2022, at the Medical Recovery Section from "Dr. Pop Mircea Municipal Hospital Pop Mircea" in Marghita. A total of 163 consecutive patients with chronic dyspnea of various etiologies were evaluated for inclusion in the study. Patients who met the inclusion criteria followed a personalized physical training program of variable duration (between 20 and 40 min) up to the limit of exercise tolerance (grade 3-4 modified Borg scale or up to 70% of maximum heart rate, calculated with the formula 220 age in years); the first 10 days, the training was supervised by a physiotherapist, then patients followed a program of 30 min of exercise 5 days/week at home for 3 months. Assessments, performed at inclusion and after 3 months of training, consisted of the 6 min walk test (6MWT) and the London Chest Activity of Daily Living (LCADL) scale. Results: Pulmonary etiology is the most common cause of dyspnea in the cohort (61.65%). The number of patients without ventilatory defects is 56, or 38.35%. The mean value of initial functional limitation (LCADL1) improved significantly after 3 months (LACDL2) of rehabilitation treatment (38% versus 26.5%); at the same time, the mean walking distance (6MWT) increased by 76 m. Conclusions: An adequate rehabilitation program and sedentary lifestyle change significantly reduce the functional limitation of the patient with chronic dyspnea and increase walking distance. Predictors for 6MWT gait test are age, LCADL score, dyspnea level, and cardiac etiology of chronic dyspnea.
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Affiliation(s)
- Kinga Vindis
- Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania; (K.V.); (N.N.); (L.I.B.)
- Department of Psycho Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania;
| | - Noemi Nemeth
- Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania; (K.V.); (N.N.); (L.I.B.)
- Department of Psycho Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania;
| | - Cristian Marge
- Department of Psycho Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania;
| | - Carmen Pantis
- Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania;
| | - Mircea Gheorghe Pop
- Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania;
| | - Manuela Simona Pop
- Department of Psycho Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania;
| | - Laura Ioana Bondar
- Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania; (K.V.); (N.N.); (L.I.B.)
- Department of Biology and Life Sciences, Faculty of Medicine, Vasile Goldiș Western University of Arad, 310048 Arad, Romania
| | | | - Katalin Babeș
- Cardiology Department, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania;
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11
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Sermsinsaithong N, Yuenyongchaiwat K, Thanawattano C, Buekban C, Kulchanarat C, Buranapuntalug S, Wattanananont K, Satdhabudha O. Effects of a Home-Based Rehabilitation Exercise Program on Cardiorespiratory Performance in Community-Dwelling Adults Who Underwent Heart Surgery: Randomized Controlled Trial. JMIR Rehabil Assist Technol 2025; 12:e68504. [PMID: 40160182 PMCID: PMC11970437 DOI: 10.2196/68504] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/07/2024] [Revised: 02/27/2025] [Accepted: 02/27/2025] [Indexed: 04/02/2025] Open
Abstract
Background Patients undergoing heart surgery demonstrate impaired cardiorespiratory performance. Phase II cardiac rehabilitation (CR) in people undergoing open heart surgery (OHS) aims to reduce the adverse physical effects of cardiovascular diseases. Virtual reality (VR) exercise is now used in CR. Objective This study aimed to explore the effects of VR exercise on functional capacity, pulmonary function, and respiratory muscle strength in patients who underwent OHS and were in phase II CR. Methods Forty-nine patients who underwent elective OHS and were in phase II CR were randomized into a VR group (N=24) and a control group (N=25). The VR group completed 8 weeks of a home-based VR exercise program, including chest trunk mobilization and aerobic circuit training for 30 minutes, whereas the control group received an exercise brochure and information regarding the benefits of exercise. Intention-to-treat analysis was conducted, and 2-way mixed ANOVA was performed to compare between- and within-group differences in functional capacity and respiratory performance. Results After completing the 8-week program, the VR group showed significant improvement in functional capacity compared to the control group (66.29, SD 25.84 m; P=.01). Inspiratory muscle strength increased in both the VR and control groups compared to baseline (9.46, SD 2.85 and 9.64, SD 2.78 cm H2O, respectively). In addition, after the 8-week intervention, significant improvements were found in expiratory muscle strength (15.79, SD 4.65 cm H2O) and forced expiratory volume in 1 second as a percentage of predicted values (2.96%, SD 1.52%) in the VR group compared to the baseline session. Conclusions The home-based VR exercise program significantly improved functional capacity but not respiratory muscle or pulmonary function.
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Affiliation(s)
- Natsinee Sermsinsaithong
- Department of Physical Therapy, Faculty of Allied Health Sciences, Thammasat University, 99 Moo 18, Paholyothin Road, Klong Luang, Pathum Thani, 12120, Thailand, 66 824521680
| | - Kornanong Yuenyongchaiwat
- Department of Physical Therapy, Faculty of Allied Health Sciences, Thammasat University, 99 Moo 18, Paholyothin Road, Klong Luang, Pathum Thani, 12120, Thailand, 66 824521680
- Thammasat University Research Unit, Physical Therapy in Respiratory and Cardiovascular Systems, Thammasat University, Pathum Thani, Thailand
| | - Chusak Thanawattano
- Biomedical Electronics and Systems Research Team, Assistive Technology and Medical Devices Research Group, National Electronics and Computer Technology Center, Pathum Thani, Thailand
| | - Chatchai Buekban
- Biomedical Electronics and Systems Research Team, Assistive Technology and Medical Devices Research Group, National Electronics and Computer Technology Center, Pathum Thani, Thailand
| | - Chitima Kulchanarat
- Physical Therapy Center, Thammasat University Hospital, Pathum Thani, Thailand
| | - Sasipa Buranapuntalug
- Department of Physical Therapy, Faculty of Allied Health Sciences, Thammasat University, 99 Moo 18, Paholyothin Road, Klong Luang, Pathum Thani, 12120, Thailand, 66 824521680
- Thammasat University Research Unit, Physical Therapy in Respiratory and Cardiovascular Systems, Thammasat University, Pathum Thani, Thailand
| | - Khanistha Wattanananont
- Cardiac Rehabilitation Unit, Excellence Center, Faculty of Medicine, Navamindradhiraj University, Bangkok, Thailand
| | - Opas Satdhabudha
- Department of Surgery, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
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12
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Verma S, Mori M, Gaudino M. Preoperative Telerehabilitation Improves Outcomes After Cardiac Surgery. J Am Coll Cardiol 2025; 85:801-803. [PMID: 39772359 DOI: 10.1016/j.jacc.2024.11.031] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/05/2024] [Revised: 11/10/2024] [Accepted: 11/12/2024] [Indexed: 02/28/2025]
Affiliation(s)
- Subodh Verma
- Division of Cardiac Surgery, St Michael's Hospital of Unity Health Toronto, Toronto, Ontario, Canada; Division of Cardiac Surgery and Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.
| | - Makoto Mori
- Division of Cardiothoracic and Vascular Surgery, Columbia University Irving Medical Center, New York, New York, USA
| | - Mario Gaudino
- Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York, USA
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13
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Arena R, Pronk NP. Rethinking obesity care in the United States: Lessons from the cardiovascular disease - Cardiac rehabilitation model. Curr Probl Cardiol 2025; 50:102966. [PMID: 39653096 DOI: 10.1016/j.cpcardiol.2024.102966] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/01/2024] [Accepted: 12/06/2024] [Indexed: 12/15/2024]
Abstract
The prevalence of obesity in the United States (U.S.), in conjunction with the myriad of detrimental health consequences associated with this disease, justifiably warrants deep concern and characterization as a national health crisis of epidemic proportions. The healthcare journey of patients suffering from and seeking treatment for obesity is, in many ways, more complex than other conditions - weight sigma, leads to negative attitudes, stereotypes, prejudice, and discrimination. A patient seeking care for obesity is often faced with having to prove their condition is not the cause of a behavioral abnormality and that their current state can be modified by lifestyle modifications, such as diet and exercise. At the same time, the infrastructure and reimbursement for lifestyle management is woefully insufficient in the current U.S. healthcare system, a system built upon disease management through pharmacotherapy and surgical options. Obesity care is evolving rapidly, and a treatment paradigm shift is needed. The magnitude and severity of the obesity epidemic demands it. Any alternative care model to be proposed should be readily scalable, sustainable, and have a strong, established, scientific foundation. Herein, we propose adopting and adapting the CVD care approach to patients diagnosed with obesity.
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Affiliation(s)
- Ross Arena
- Department of Physical Therapy, College of Applied Science, University of Illinois, 1919 W. Taylor Street (MC 898), Chicago, IL 60612, United States; Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, United States; HealthPartners Institute, Minneapolis, MN, United States.
| | - Nicolaas P Pronk
- Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, United States; HealthPartners Institute, Minneapolis, MN, United States; Department of Health Policy and Management, University of Minnesota, Minneapolis, MN, United States
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14
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Brown TM, Pack QR, Beregg EA, Brewer LC, Ford YR, Forman DE, Gathright EC, Khadanga S, Ozemek C, Thomas RJ. Core Components of Cardiac Rehabilitation Programs: 2024 Update: A Scientific Statement From the American Heart Association and the American Association of Cardiovascular and Pulmonary Rehabilitation: Endorsed by the American College of Cardiology. J Cardiopulm Rehabil Prev 2025; 45:E6-E25. [PMID: 39820221 DOI: 10.1097/hcr.0000000000000930] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 01/19/2025]
Abstract
The science of cardiac rehabilitation and the secondary prevention of cardiovascular disease has progressed substantially since the most recent American Heart Association and American Association of Cardiovascular and Pulmonary Rehabilitation update on the core components of cardiac rehabilitation and secondary prevention programs was published in 2007. In addition, the advent of new care models, including virtual and remote delivery of cardiac rehabilitation services, has expanded the ways that cardiac rehabilitation programs can reach patients. In this scientific statement, we update the scientific basis of the core components of patient assessment, nutritional counseling, weight management and body composition, cardiovascular disease and risk factor management, psychosocial management, aerobic exercise training, strength training, and physical activity counseling. In addition, in recognition that high-quality cardiac rehabilitation programs regularly monitor their processes and outcomes and engage in an ongoing process of quality improvement, we introduce a new core component of program quality. High-quality program performance will be essential to improve widely documented low enrollment and adherence rates and reduce health disparities in cardiac rehabilitation access.
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15
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Yang Y, Lv Q, Zhang X, Wu Q, Li L, Ye X, Wang S. Effects of high-intensity interval training on cardiorespiratory function in coronary artery disease: An overview of systematic reviews. Ann Phys Rehabil Med 2025; 68:101878. [PMID: 39657367 DOI: 10.1016/j.rehab.2024.101878] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/21/2023] [Revised: 06/14/2024] [Accepted: 06/18/2024] [Indexed: 12/12/2024]
Abstract
BACKGROUND Exercise-based cardiac rehabilitation has been identified as a crucial component in mitigating all-cause mortality among individuals diagnosed with coronary artery disease (CAD). Nevertheless, the optimal exercise prescription remains elusive. OBJECTIVE The purpose of this overview is to conduct a systematic evaluation and synthesis of the evidence derived from systematic reviews/meta-analyses (SRs/MAs) regarding the effects on cardiorespiratory fitness and safety of high-intensity interval training (HIIT) compared to moderate-intensity continuous training (MICT) for CAD. METHODS SRs/MAs were searched across 5 databases from inception until March 22, 2023. We assessed methodological quality using the Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR-2). The risk of bias, reporting, and evidence were evaluated using the Risk of Bias in Systematic Reviews (ROBIS) tool, the Preferred Reporting Item for Systematic Review and Meta-analysis (PRISMA) 2020, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system, respectively. RESULTS In total, 9 SRs/MAs were included. Based on the AMSTAR-2 criteria, 4 and 5 studies were considered low- and critically-low quality, respectively. None of the studies reported all 27 items outlined in the PRISMA 2020 checklist. Regarding the ROBIS evaluation, 4 reviews were rated as low risk, 4 as high risk, and 1 as unclear risk. The GRADE evaluation indicated 3 high-level evidence, 20 moderate-level evidence, 28 low-level evidence, and 34 very low-level evidence studies based on 85 indicators. Moderate- to high-quality evidence supported that HIIT is superior to MICT in improving VO2peak for CAD. CONCLUSION The efficacy and time cost of developing cardiorespiratory fitness support HIIT as an adjunct or alternative to MICT. The evidence does not permit a definitive decision regarding the adverse effects of HIIT compared to MICT. Because of the insufficient quality of the evidence, future studies should focus more on the quality of randomized controlled trials and evidence for SRs/MAs to provide scientific and robust evidence for conclusions. TRIAL REGISTRATION The review was registered at PROSPERO: CRD42023420015.
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Affiliation(s)
- Yingtian Yang
- Department of Cardiovascular Internal Medicine, Guang 'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, PR China
| | - Qianyu Lv
- Department of Cardiovascular Internal Medicine, Guang 'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, PR China
| | - Xirui Zhang
- Department of Geriatrics, Baogang Hospital, Inner Mongolia Medical College Third Affiliated Hospital, Baotou 014010, PR China
| | - Qian Wu
- Department of Cardiovascular Internal Medicine, Guang 'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, PR China
| | - Lanlan Li
- Department of Cardiovascular Internal Medicine, Guang 'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, PR China
| | - Xuejiao Ye
- Department of Cardiovascular Internal Medicine, Guang 'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, PR China
| | - Shihan Wang
- Department of Cardiovascular Internal Medicine, Guang 'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, PR China.
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16
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Ramesh SH, Jull D, Fournier H, Rajabiyazdi F. Exploring Barriers to Patients' Progression in the Cardiac Rehabilitation Journey From Health Care Providers' Perspectives: Qualitative Study. Interact J Med Res 2025; 14:e66164. [PMID: 39983120 PMCID: PMC11890148 DOI: 10.2196/66164] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/05/2024] [Revised: 01/15/2025] [Accepted: 01/21/2025] [Indexed: 02/23/2025] Open
Abstract
BACKGROUND Cardiovascular diseases are one of the leading causes of mortality globally. Cardiac rehabilitation (CR) programs are crucial for patients recovering from cardiac events, as they help reduce the risk of recurrent events and support patient recovery. The patient's journey in CR spans the stages before, during, and after the program. Patients have to progress through each stage of CR programs successfully to complete the entire CR journey and get the full benefits of CR programs, but numerous barriers within this journey can hinder patient progression. OBJECTIVE This study aims to explore the barriers to progression at all stages of the CR patient journey from the perspectives of health care providers involved in CR care. METHODS This qualitative study involved semistructured interviews with health care providers involved in CR care from July 2023 to January 2024. A purposive maximal variation sampling method was used to target providers with diverse demographics and specialties. Snowball sampling was used to recruit participants, leveraging the existing networks of participants. Each interview lasted between 30 and 45 minutes. Interviews were recorded, transcribed verbatim, and analyzed using an inductive thematic analysis approach. Data analysis was conducted from August 2023 to February 2024. RESULTS Ten health care providers, comprising 7 females and 3 males, were interviewed. Their roles included physician, program director, nurse manager, clinical manager, nurse coordinator, nurse, physiotherapist, and kinesiologist. The analysis identified four overarching themes related to barriers to progression in the CR journey: (1) patients not being referred to CR programs, (2) patients not enrolling in CR programs, (3) patients dropping out of CR programs, and (4) patients' lack of adherence to lifestyle changes post-CR programs. CONCLUSIONS In light of the growing interest in technological interventions in CR programs, we proposed 4 potential technological solutions to address the barriers to progression identified in our analysis. These solutions aim to provide a foundation for future research to guide the development of effective technologies and enhance patient progression within the CR journey.
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Affiliation(s)
- Shri Harini Ramesh
- Department of Systems and Computer Engineering, Faculty of Engineering and Design, Carleton University, Ottawa, ON, Canada
| | - Darwin Jull
- Department of Systems and Computer Engineering, Faculty of Engineering and Design, Carleton University, Ottawa, ON, Canada
| | | | - Fateme Rajabiyazdi
- Department of Systems and Computer Engineering, Faculty of Engineering and Design, Carleton University, Ottawa, ON, Canada
- Bruyère Research Institute, Bruyère, Ottawa, ON, Canada
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17
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Aleksova A, Fluca AL, Beltrami AP, Dozio E, Sinagra G, Marketou M, Janjusevic M. Part 2-Cardiac Rehabilitation After an Acute Myocardial Infarction: Timing and Gender Differences in Adherence; Where Do We Stand? J Clin Med 2025; 14:1189. [PMID: 40004720 PMCID: PMC11856719 DOI: 10.3390/jcm14041189] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/18/2024] [Revised: 02/06/2025] [Accepted: 02/11/2025] [Indexed: 02/27/2025] Open
Abstract
Cardiac rehabilitation is a beneficial multidisciplinary interventional protocol that improves cardiovascular health and reduces mortality and morbidity rates in patients with cardiovascular diseases. Multiple studies have demonstrated that the implementation of such protocols in patients with acute myocardial infarction (MI) dramatically improved patients' outcome. It is unfortunate that in practice, in spite of the advantages of cardiac rehabilitation, this approach is seldom employed. Indeed, only some guidance, such as American College of Cardiology and European Society of Cardiology guidelines, recommends cardiac rehabilitation in their protocols. In particular, the European guideline recommends its early implementation while the patient is still in hospital, whereas the American guideline suggests that it should be approximately three weeks after discharge. In Part 1 of this two-part comprehensive review, we provided a historical overview of cardiac rehabilitation, a detailed examination of each component of the cardiac rehabilitation programme, and its impact on cardiovascular health. In Part 2, the objective was to provide a comprehensive explanation of the optimal timing for the commencement of the cardiac rehabilitation programme, and to elucidate the factors that influence low engagement in such programmes, as well as the gender-based differences in adherence.
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Affiliation(s)
- Aneta Aleksova
- Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, 34100 Trieste, Italy; (A.L.F.); (G.S.); (M.J.)
- Department of Medical Surgical and Health Sciences, University of Trieste, 34125 Trieste, Italy
| | - Alessandra Lucia Fluca
- Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, 34100 Trieste, Italy; (A.L.F.); (G.S.); (M.J.)
- Department of Medical Surgical and Health Sciences, University of Trieste, 34125 Trieste, Italy
| | - Antonio Paolo Beltrami
- Dipartimento di Area Medica (DAME), Istituto di Patologia Clinica, University of Udine, 33100 Udine, Italy;
| | - Elena Dozio
- Department of Biomedical Sciences for Health, University of Milan, 20122 Milan, Italy;
| | - Gianfranco Sinagra
- Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, 34100 Trieste, Italy; (A.L.F.); (G.S.); (M.J.)
- Department of Medical Surgical and Health Sciences, University of Trieste, 34125 Trieste, Italy
| | - Maria Marketou
- Cardiology Department Crete, School of Medicine, Heraklion University General Hospital, University of Crete, 700 13 Heraklion, Greece;
| | - Milijana Janjusevic
- Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, 34100 Trieste, Italy; (A.L.F.); (G.S.); (M.J.)
- Department of Medical Surgical and Health Sciences, University of Trieste, 34125 Trieste, Italy
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18
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Gibson I, Jennings C, Neubeck L, Corcoran M, Wood D, Sharif F, Hynes L, Murphy AW, Byrne M, McEvoy JW. Using a digital health intervention "INTERCEPT" to improve secondary prevention in coronary heart disease (CHD) patients: protocol for a mixed methods non-randomised feasibility study. HRB Open Res 2025; 6:43. [PMID: 38414839 PMCID: PMC10897504 DOI: 10.12688/hrbopenres.13781.1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 11/26/2024] [Indexed: 02/29/2024] Open
Abstract
Background Digital health interventions (DHIs) are increasingly used for the secondary prevention of cardiovascular disease (CVD). The aim of this study is to determine the feasibility of "INTERCEPT", a co-designed DHI developed to improve secondary prevention in hospitalised coronary heart disease patients (CHD). Methods This non-randomised, pilot feasibility study with embedded process evaluation will be conducted with a sample of 40 patients in an acute hospital setting. Informed by behaviour change theory, INTERCEPT integrates a smartphone interface, health care professional portal, a fitness wearable and a blood pressure monitor. INTERCEPT is designed to support and motivate patients to set goals, self-monitor lifestyle and medical risk factors, and manage their medications, with the health care professional portal enabling monitoring and communication with patients. Using consecutive sampling, eligible patients will be recruited in two phases, a pre-implementation phase and an implementation phase. Commencing with pre-implementation (1 month duration), participants will not immediately receive INTERCEPT, however, they will be invited to receive INTERCEPT at 3 months follow-up. This will enable early learning about the processes of recruitment and conducting the assessment prior to full scale deployment of INTERCEPT in the next step implementation phase. During the implementation phase (2 months duration), participants will be invited to download INTERCEPT to their smartphone prior to hospital discharge. Qualitative interviews will be conducted among a subset of patients and health care professionals to gain a greater insight into their experience of using INTERCEPT. Primary outcomes will be assessed at baseline and 3-month follow-up. Using pre-defined feasibility criteria, including recruitment, retention and engagement rates, together with data on intervention acceptability, will determine the appropriateness of progressing to a definitive trial. Discussion This study will provide important insights to help inform the feasibility of conducting a definitive trial of "INTERCEPT" among coronary heart disease patients in a critical health care setting.
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Affiliation(s)
- Irene Gibson
- School of Medicine, University of Galway, Galway, Ireland
- National Institute for Prevention and Cardiovascular Health, Galway, Ireland
| | - Catriona Jennings
- School of Medicine, University of Galway, Galway, Ireland
- National Institute for Prevention and Cardiovascular Health, Galway, Ireland
| | - Lis Neubeck
- School of Health and Social Care, Edinburgh Napier University, Edinburgh, UK
| | | | - David Wood
- School of Medicine, University of Galway, Galway, Ireland
- National Institute for Prevention and Cardiovascular Health, Galway, Ireland
| | - Faisal Sharif
- School of Medicine, University of Galway, Galway, Ireland
| | - Lisa Hynes
- Croí, West of Ireland Cardiac Foundation, Galway, Ireland
| | - Andrew W Murphy
- Discipline of General Practice, University of Galway, Galway, Ireland
| | - Molly Byrne
- Health Behaviour Change Research Group, University of Galway, Galway, Ireland
| | - John William McEvoy
- School of Medicine, University of Galway, Galway, Ireland
- National Institute for Prevention and Cardiovascular Health, Galway, Ireland
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19
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Su JJ, Pepera G, Antoniou V, Batalik L. Adapting cardiac telerehabilitation from research evidence to real-world implementation: engaging stakeholders. Eur J Cardiovasc Nurs 2025; 24:126-127. [PMID: 39471325 DOI: 10.1093/eurjcn/zvae143] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/14/2024] [Accepted: 10/15/2024] [Indexed: 11/01/2024]
Affiliation(s)
- Jing Jing Su
- School of Nursing, Tung Wah College, Hong Kong, China
| | - Garyfallia Pepera
- Clinical Exercise Physiology and Rehabilitation Research Laboratory Department of Physiotherapy, Faculty of Health Sciences, University of Thessaly, Lamia, Greece
| | - Varsamo Antoniou
- Clinical Exercise Physiology and Rehabilitation Research Laboratory Department of Physiotherapy, Faculty of Health Sciences, University of Thessaly, Lamia, Greece
| | - Ladislav Batalik
- Department of Rehabilitation, University Hospital Brno, Jihlavska 20, 62500 Brno, Czech Republic
- Department of Physiotherapy and Rehabilitation, Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic
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20
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Wingood M, Vincenzo JL, Goyal P, Brach JS. Clin-STAR Corner: Rehabilitation for Older Adults With Heart Failure. J Am Geriatr Soc 2025. [PMID: 39865546 DOI: 10.1111/jgs.19346] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/09/2024] [Revised: 12/05/2024] [Accepted: 12/12/2024] [Indexed: 01/28/2025]
Abstract
Heart failure is a major contributor to morbidity, mortality, and healthcare costs, especially among older adults. Despite a large body of evidence supporting the benefits of cardiac rehabilitation, less than 30% of eligible Medicare beneficiaries participate in cardiac rehabilitation. Thus, it is essential to examine alternatives, such as physical rehabilitation, a rehabilitation approach that focuses on physical activity and function. We systematically identified and summarized four key articles published between 2022 and 2024 that highlight innovations in rehabilitation with the potential of increasing utilization. These articles emphasize three areas of opportunity: (1) home-based telerehabilitation; (2) research focused on underrepresented and underserved populations; and (3) economic evaluations. Additional research on alternative modes of cardiac or physical rehabilitation, strategies to address heart failure-related health inequities, and implementation studies incorporating cost-effectiveness are needed to support increased utilization of cardiac and physical rehabilitation.
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Affiliation(s)
- Mariana Wingood
- Department of Implementation Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
- Section of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
| | - Jennifer L Vincenzo
- Department of Physical Therapy, College of Health Professions, University of Arkansas for Medical Sciences Northwest, Fayetteville, Arkansas, USA
- Center for Implementation Research, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
| | - Parag Goyal
- Department of Medicine, Weill Cornell Medicine, New York, New York, USA
| | - Jennifer S Brach
- Department of Physical Therapy, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
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21
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Bomtempo APD, Main E, Ghisi GLDM. Remote Exercise Engagement Among Individuals With Cardiovascular Disease: A Systematic Review of Barriers and Facilitators. J Cardiopulm Rehabil Prev 2025; 45:8-19. [PMID: 39298562 DOI: 10.1097/hcr.0000000000000899] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 09/22/2024]
Abstract
PURPOSE To systematically review the literature regarding barriers and facilitators to remote exercise among individuals with cardiovascular diseases (CVD). REVIEW METHODS Six databases were searched (inception-December 2023). Studies including barriers and facilitators for remote exercise reported by individuals living with CVD were considered. Quality was rated using the Mixed Methods Assessment Tool (MMAT). Results were synthesized following a thematic analysis approach. Characteristics of interventions were reported using the Template for Intervention Description and Replication (TIDieR). SUMMARY From an initial pool of 8543 records, 18 studies met the inclusion criteria. Among these, 13 were qualitative studies, with individual interviews being the most frequent data extraction method. Nine studies received 5/5 MMAT scores (ie, high quality). Twelve studies reported remote exercise interventions, mostly delivered within cardiac rehabilitation, by physiotherapists, nurses, and dietitians, predominantly via telephone calls or videoconferences, with only one study incorporating text messages. Five key themes influencing remote exercise interventions were identified: technology (encompassing access and literacy, self-monitoring/motivation, and security concerns), individual health considerations (health/personal aspects and coronavirus disease-2019), social factors (support from health care team and family/social support), environment (facilities), and logistical factors (time and displacement). Several themes served as both facilitators and barriers. Key insights for remote exercise interventions included mobile accessibility, interactive chat sessions, minimal click interactions, short sessions, personalized feedback, and flexible timing. Results emphasize the importance of promoting social interaction and support between participants and health care teams to mitigate barriers and enhance facilitators in remote exercise interventions for individuals with CVD.
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Affiliation(s)
- Ana Paula Delgado Bomtempo
- Author Affiliations: Graduate Program in Physical Education, Faculty of Physical Education and Sports, Federal University of Juiz de Fora, Brazil (Ms Bomtempo); Library & Information Services, University Health Network, Toronto Rehabilitation Institute, Toronto, Canada (Ms Main); KITE - Toronto Rehabilitation Institute, University Health Network, University of Toronto, Canada (Dr Ghisi); and Department of Physical Therapy, Temerty Faculty of Medicine, University of Toronto, Toronto, Canada (Dr Ghisi)
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22
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Nakayama A, Iwata T, Sakuma H, Kashino K, Tomoike H. Predicting Heart Rate at the Anaerobic Threshold Using a Machine Learning Model Based on a Large-Scale Population Dataset. J Clin Med 2024; 14:21. [PMID: 39797104 PMCID: PMC11722178 DOI: 10.3390/jcm14010021] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/20/2024] [Revised: 12/12/2024] [Accepted: 12/20/2024] [Indexed: 01/13/2025] Open
Abstract
Background/Objectives: For effective exercise prescription for patients with cardiovascular disease, it is important to determine the target heart rate at the level of the anaerobic threshold (AT-HR). The AT-HR is mainly determined by cardiopulmonary exercise testing (CPET). The aim of this study is to develop a machine learning (ML) model to predict the AT-HR solely from non-exercise clinical features. Methods: From consecutive 21,482 cases of CPET between 2 February 2008 and 1 December 2021, an appropriate subset was selected to train our ML model. Data consisted of 78 features, including age, sex, anthropometry, clinical diagnosis, cardiovascular risk factors, vital signs, blood tests, and echocardiography. We predicted the AT-HR using a ML method called gradient boosting, along with a rank of each feature in terms of its contribution to AT-HR prediction. The accuracy was evaluated by comparing the predicted AT-HR with the target HRs from guideline-recommended equations in terms of the mean absolute error (MAE). Results: A total of 8228 participants included healthy individuals and patients with cardiovascular disease and were 62 ± 15 years in mean age (69% male). The MAE of the AT-HR by the ML-based model was 7.7 ± 0.2 bpm, which was significantly smaller than those of the guideline-recommended equations; the results using Karvonen formulas with the coefficients 0.7 and 0.4 were 34.5 ± 0.3 bpm and 11.9 ± 0.2 bpm, respectively, and the results using simpler formulas, rest HR + 10 and +20 bpm, were 15.9 ± 0.3 and 9.7 ± 0.2 bpm, respectively. The feature ranking method revealed that the features that make a significant contribution to AT-HR prediction include the resting heart rate, age, N-terminal pro-brain natriuretic peptide (NT-proBNP), resting systolic blood pressure, highly sensitive C-reactive protein (hsCRP), cardiovascular disease diagnosis, and β-blockers, in that order. Prediction accuracy with the top 10 to 20 features was comparable to that with all features. Conclusions: An accurate prediction model of the AT-HR from non-exercise clinical features was proposed. We expect that it will facilitate performing cardiac rehabilitation. The feature selection technique newly unveiled some major determinants of AT-HR, such as NT-proBNP and hsCRP.
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Affiliation(s)
- Atsuko Nakayama
- Department of Cardiovascular Medicine, Sakakibara Heart Institute, Tokyo 183-0003, Japan
- Department of Cardiovascular Medicine, University of Tokyo, Tokyo 113-8654, Japan
| | - Tomoharu Iwata
- NTT Communication Science Laboratories, NTT Corporation, Kanagawa-ken 243-0198, Japan
- NTT Basic Research Laboratories, NTT Corporation, Kanagawa-ken 243-0198, Japan
| | - Hiroki Sakuma
- NTT Communication Science Laboratories, NTT Corporation, Kanagawa-ken 243-0198, Japan
- NTT Basic Research Laboratories, NTT Corporation, Kanagawa-ken 243-0198, Japan
| | - Kunio Kashino
- NTT Communication Science Laboratories, NTT Corporation, Kanagawa-ken 243-0198, Japan
- NTT Basic Research Laboratories, NTT Corporation, Kanagawa-ken 243-0198, Japan
| | - Hitonobu Tomoike
- Department of Cardiovascular Medicine, Sakakibara Heart Institute, Tokyo 183-0003, Japan
- NTT Basic Research Laboratories, NTT Corporation, Kanagawa-ken 243-0198, Japan
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Shah ND, Banta CW, Berger AL, Hattenberger A, Zimmerman A, Martin BE, Wu E, Majumdar U, Kirchner HL, Matsumura ME. Retrospective Comparison of Outcomes and Cost of Virtual Versus Center-Based Cardiac Rehabilitation Programs. J Am Heart Assoc 2024; 13:e036861. [PMID: 39673292 PMCID: PMC11935551 DOI: 10.1161/jaha.124.036861] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/29/2024] [Accepted: 11/06/2024] [Indexed: 12/16/2024]
Abstract
BACKGROUND Despite robust evidence supporting an association with improved outcomes in eligible patients, cardiac rehabilitation (CR) remains underused, with a minority of eligible patients participating. Virtual cardiac rehabilitation (VCR) has been proposed as an alternative to traditional center-based CR (CBCR) to improve usage rates. However, data supporting the efficacy and cost-effectiveness of VCR are limited. In the present study, we compared the outcomes and cost of a VCR versus traditional CBCR program. METHODS AND RESULTS In a retrospective cohort study comparing VCR versus CBCR, CBCR data were collected from a period of January 2018 to September 2023. VCR data were collected from program initiation in July 2021 to September 2023. Primary health outcomes measured were 1-year mortality rates, recurrent myocardial infarction, all-cause hospital readmission, and emergency department visits. Primary cost outcomes were analyzed as cost ratios related to VCR versus CBCR assessing total medical costs allowed, pharmacy costs, and total costs of care over the 12 months post-CR enrollment. VCR was associated with a significant reduction in 1-year all-cause hospital readmission (incident rate ratio [IRR], 0.616 [95% CI, 0.489-0.777], P<0.001) and ED admission (IRR, 0.557 [95% CI, 0.452-0.687], P<0.001) at 1 year. The IRR of myocardial infarction and all-cause mortality did not significantly differ between VCR and CBCR. In addition, VCR was associated with significant reductions in medically related (cost ratio, 0.814 [95% CI, 0.690-0.960], P=0.0144) and total costs allowed (cost ratio, 0.838 [95% CI, 0.725-0.970], P=0.0176). CONCLUSIONS VCR is a viable alternative to CBCR with at least comparable efficacy and cost, and as such, represents a key mechanism for improving access to and participation in CR for eligible patients.
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Su JJ, Wong AKC, He XF, Zhang LP, Cheng J, Lu LJ, Lan L, Wang Z, Lin RS, Batalik L. Feasibility and effectiveness of cardiac telerehabilitation for older adults with coronary heart disease: A pilot randomized controlled trial. Contemp Clin Trials Commun 2024; 42:101365. [PMID: 39319320 PMCID: PMC11421251 DOI: 10.1016/j.conctc.2024.101365] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/26/2024] [Revised: 07/30/2024] [Accepted: 09/08/2024] [Indexed: 09/26/2024] Open
Abstract
BACKGROUND Cardiac rehabilitation is a beneficial multidisciplinary treatment of exercise promotion, patient education, risk factor management, and psychosocial counseling for people with coronary heart disease (CHD) that is underutilized due to substantial disparities in access, referral, and participation. Empirical studies suggest that cardiac telerehabilitation (CTR) have safety and efficacy comparable to traditional in-person cardiac rehabilitation, however, older adults are under-reported with effectiveness, feasibility, and usability remains unclear. METHODS The study randomized 43 older adults (84 % males) to the 12-week CTR intervention or standard of care. Guided by Social Cognitive Theory, participants received individualized in-person assessment and e-coaching sessions, followed by CTR usage at home. Data were collected at baseline (T0), six-week (T1), and 12-week (T2). RESULTS Participants in the CTR intervention group showed significant improvement in daily steps (T1: β = 4126.58, p = 0.001; T2: β = 5285, p = 0.01) and health-promoting lifestyle profile (T1: β = 23.26, p < 0.001; T2: β = 12.18, p = 0.008) across study endpoints. Twenty participants completed the intervention, with 40 % used the website for data-uploading or experiential learning, 90 % used the pedometer for tele-monitoring. Improving awareness of rehabilitation and an action focus were considered key facilitators while physical discomforts and difficulties in using the technology were described as the main barriers. CONCLUSIONS The CTR is feasible, safe and effective in improving physical activity and healthy behaviors in older adults with CHD. Considering the variation in individual cardiovascular risk factors, full-scale RCT with a larger sample is needed to determine the effect of CTR on psychological symptoms, body weight and blood pressure, and quality of life.
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Affiliation(s)
| | | | - Xi-Fei He
- Department of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, China
| | - Li-ping Zhang
- Department of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, China
| | - Jie Cheng
- Department of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, China
| | - Li-Juan Lu
- Department of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, China
| | - Lan Lan
- Department of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, China
| | - Zhaozhao Wang
- Department of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, China
| | - Rose S.Y. Lin
- Elaine Hubbard Center for Nursing Research on Aging, School of Nursing, University of Rochester Medical Center, USA
| | - Ladislav Batalik
- Department of Rehabilitation, University Hospital Brno, Brno, Czech Republic
- Department of Physiotherapy and Rehabilitation, Faculty of Medicine, Masaryk University, Brno, Czech Republic
- Department of Public Health, Faculty of Medicine, Masaryk University, Brno, Czech Republic
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Wang X, Chen D, Zou P, Zhang H, Qiu X, Xu L, Lee G. Understanding adaptive tasks in cardiac rehabilitation among patients with acute myocardial infarction: a qualitative study. Ann Med 2024; 56:2311227. [PMID: 38306095 PMCID: PMC10840589 DOI: 10.1080/07853890.2024.2311227] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/22/2023] [Accepted: 01/19/2024] [Indexed: 02/03/2024] Open
Abstract
BACKGROUND While Cardiac Rehabilitation (CR) programs have shown effectiveness in improving cardiac outcomes, there is limited understanding of how patients perceive and adapt to these interventions. Furthermore, alternative modes of delivering CR that have received positive evaluations from participants remain underexplored, yet they have the potential to enhance CR uptake. OBJECTIVES To explore the patient experience in CR programmes following Acute Myocardial Infarction (AMI) and describe their adaptive processing. PATIENTS AND METHODS This qualitative study was conducted at a nationally certified centre in China between July 2021 and September 2022, encompassing three stages: in-hospital, centre-based, and home-based CR programs. Purposive sampling was used to select eligible AMI patients for in-depth semi-structured interviews. The interview outline and analytical framework were aligned with the key concepts derived from the middle-range theory of adaptation to chronic illness and the normalization process theory. The findings were reported following the Consolidated Criteria for Reporting Qualitative Research checklist. RESULTS Forty AMI patients were recruited. Four main themes describing the process of AMI patients normalizing CR intervention were identified, including (1) experiencing CR service driving by role's responsibilities, (2) engaging in collaborative relationship based on interpersonal trust, (3) exploring a personalized rehabilitation plan by complex integration, and (4) expecting a promised outcome to shape decision-making. CONCLUSION Integrated care interventions for AMI patients could benefit from a collaborative co-designed approach to ensure that CR interventions are normalized and fit into patients' daily lives. Organizational-level CR services should align with the rehabilitation needs and expectations of patients.
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Affiliation(s)
- Xiyi Wang
- School of Nursing, Shanghai Jiao Tong University, Shanghai, China
| | - Dandan Chen
- School of Nursing, Zhejiang University School of Medicine, Zhejiang, China
| | - Ping Zou
- School of Nursing, Nipissing University, Toronto, Ontario, Canada
| | - Hui Zhang
- Department of Cardiology, Guizhou Provincial People’s Hospital, Guizhou, China
| | - Xunhan Qiu
- Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
| | - Li Xu
- Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
| | - Geraldine Lee
- Catherine McAuley School of Nursing & Midwifery, Brookfield Health Sciences Complex, University College Cork, Cork, Ireland
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Supervia M, Bomtempo APD, Gómez E, Bonikowske AR, Arroyo-Riaño MO, Ghisi GLDM. Enhancing cardiovascular patients' knowledge of air pollution: a pilot study evaluating the impact of an educational intervention in cardiac rehabilitation. FRONTIERS IN REHABILITATION SCIENCES 2024; 5:1495621. [PMID: 39649374 PMCID: PMC11621042 DOI: 10.3389/fresc.2024.1495621] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 09/13/2024] [Accepted: 10/30/2024] [Indexed: 12/10/2024]
Abstract
Introduction Air pollution poses significant risks to cardiovascular health, yet patients often lack comprehensive knowledge about its impact and mitigation strategies. This study aims to evaluate the effectiveness of an educational intervention within a cardiac rehabilitation (CR) context in enhancing patients' understanding of air pollution and its cardiovascular effects. Methods A pre-post pilot study was conducted from February 2021 to June 2021 at the Gregorio Marañón University General Hospital, Madrid, Spain. A total of 43 patients with cardiovascular disease attending CR were enrolled. Participants received a 1-h educational intervention delivered either in-person or online, focusing on the effects of air pollution and strategies to reduce exposure. Pre- and post-intervention questionnaires assessed participants' knowledge and perceptions. Descriptive statistics were used to analyze changes in awareness and understanding. Results Initially, participants demonstrated a high level of awareness about the health impacts of air pollution, with 100% acknowledging its effects on health. However, detailed knowledge about specific concepts such as the Air Quality Index (AQI) and particulate matter (PM2.5) was limited. Post-intervention, there was a significant increase in knowledge, with familiarity with AQI rising from 61% to 81% (p = 0.02) and understanding of PM2.5 improving from 28% to 58% (p = 0.01). This indicates that the educational intervention effectively bridged gaps in understanding and reinforced the importance of environmental factors in cardiovascular health management. Discussion The pilot study highlights the critical role of targeted education in improving patient awareness and knowledge about air pollution. The significant improvement in understanding key concepts underscores the need for broader educational initiatives that extend beyond CR programs. Future research should explore the impact of such interventions on long-term health outcomes and consider expanding educational efforts to include healthcare providers and family members.
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Affiliation(s)
- Marta Supervia
- Department of Physical Medicine and Rehabilitation Gregorio Marañón General University Hospital, Gregorio Marañón Health Research Institute, Madrid, Spain
- Radiology, Rehabilitation and Physiotherapy Department, Complutense University School of Medicine, Madrid, Spain
- Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, NY, United States
| | - Ana Paula Delgado Bomtempo
- Graduate Program in Physical Education, Faculty of Physical Education and Sports, Federal University of Juiz de Fora, Juiz de Fora, Brazil
| | - Eduardo Gómez
- Department of Physical Medicine and Rehabilitation Gregorio Marañón General University Hospital, Gregorio Marañón Health Research Institute, Madrid, Spain
| | - Amanda R. Bonikowske
- Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, NY, United States
| | - Maria Olga Arroyo-Riaño
- Department of Physical Medicine and Rehabilitation Gregorio Marañón General University Hospital, Gregorio Marañón Health Research Institute, Madrid, Spain
| | - Gabriela Lima de Melo Ghisi
- KITE Research Institute, University Health Network, Toronto, ON, Canada
- Department of Physical Therapy, University of Toronto, Toronto, ON, Canada
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Morici N, Ambrosetti M, Cianflone D, Calabrò P, Piepoli M. Closing the gap between WHO projections and actual need for cardiac rehabilitation in Europe. Eur J Prev Cardiol 2024; 31:e115-e116. [PMID: 37610737 DOI: 10.1093/eurjpc/zwad277] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/04/2023] [Revised: 08/16/2023] [Accepted: 08/18/2023] [Indexed: 08/24/2023]
Affiliation(s)
- Nuccia Morici
- Cardiac Rehabilitation, IRCCS S. Maria Nascente-Fondazione Don Carlo Gnocchi ONLUS, Via Capecelatro, 66, Milan 20100, Italy
| | - Marco Ambrosetti
- Cardiovascular Rehabilitation Unit, ASST Crema, Santa Marta Hospital, Rivolta D'Adda, Italy
| | | | - Paolo Calabrò
- Cardiovascular Rehabilitation Unit, AORN Sant'Anna e San Sebastiano, Caserta, Italy
| | - Massimo Piepoli
- Clinical Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy
- Department of Biomedical Science for Health, University of Milan, Milan, Italy
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Pack QR, Keys T, Priya A, Pekow PS, Keteyian SJ, Thompson MP, D’Aunno T, Lindenauer PK, Lagu T. Is 70% Achievable? Hospital-Level Variation in Rates of Cardiac Rehabilitation Use Among Medicare Beneficiaries. JACC. ADVANCES 2024; 3:101275. [PMID: 39741644 PMCID: PMC11686055 DOI: 10.1016/j.jacadv.2024.101275] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 05/30/2024] [Revised: 07/19/2024] [Accepted: 08/06/2024] [Indexed: 01/03/2025]
Abstract
Background Despite national goals to enroll 70% of cardiac rehabilitation (CR)-eligible patients, enrollment remains low. Objectives The purpose of this study was to evaluate how the treating hospital influences CR enrollment nationally. Methods We included Fee-for-Service Medicare beneficiaries aged ≥66 years who were hospitalized for acute myocardial infarction, coronary artery bypass grafting, percutaneous coronary intervention, or heart valve repair/replacement. We examined: 1) a risk-standardized model to assess comparative hospital rates; 2) a linear regression model to identify hospital factors associated with rates of risk-standardized CR; and 3) a hierarchical generalized linear model to calculate the hospital median OR. Results At 3,420 hospitals, we identified 264,970 eligible patients. A minority of hospitals (n = 1,446; 38%) performed cardiac surgery, but these hospitals cared for the majority (n = 242,875; 92%) of all eligible patients. Subsequent analyses were limited to these hospitals. The median risk-standardized CR enrollment rate was low (22%) and varied 10-fold across hospitals (10th, 90th percentile: 3%, 42%). Factors associated with higher hospital performance were Midwest location, higher number of hospital beds, directly affiliated CR program, and <1 mile distance between the hospital and closest CR facility. The national hospital median OR was 2.1. Conclusions The treating hospital plays a key role in facilitating CR enrollment after discharge. Fewer than 1% of U.S. hospitals achieved a risk-standardized CR enrollment rate of >70%. Hospitals with cardiac surgery capability care for more than 90% of all CR-eligible patients and may be a logical place to focus improvement efforts.
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Affiliation(s)
- Quinn R. Pack
- Department of Healthcare Delivery and Population Sciences, University of Massachusetts Chan Medical School–Baystate, Springfield, Massachusetts, USA
| | - Taylor Keys
- Department of Medicine and Center for Health Services and Outcomes Research, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
| | - Aruna Priya
- Department of Healthcare Delivery and Population Sciences, University of Massachusetts Chan Medical School–Baystate, Springfield, Massachusetts, USA
| | - Penelope S. Pekow
- Department of Healthcare Delivery and Population Sciences, University of Massachusetts Chan Medical School–Baystate, Springfield, Massachusetts, USA
| | - Steven J. Keteyian
- Division of Cardiovascular Medicine, Henry Ford Hospital and Medical Group, Detroit, Michigan, USA
| | - Michael P. Thompson
- Department of Cardiac Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA
| | - Thomas D’Aunno
- New York University Wagner Graduate School of Public Service, New York, New York, USA
| | - Peter K. Lindenauer
- Department of Healthcare Delivery and Population Sciences, University of Massachusetts Chan Medical School–Baystate, Springfield, Massachusetts, USA
| | - Tara Lagu
- Department of Medicine and Center for Health Services and Outcomes Research, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
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Gopal A, Detroyer I, de Alcantara Lima N, Ramappa P. Improved Cardiac Rehabilitation Referral Rates following Coronary Artery Bypass Graft and Heart Valve Replacement in an Inner-City Veteran Population. Am J Med Qual 2024; 39:280-284. [PMID: 39472764 DOI: 10.1097/jmq.0000000000000206] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/11/2025]
Abstract
Cardiac rehabilitation (CR) is underutilized due to various barriers, despite its known benefits in decreasing 5-year mortality after cardiac surgery. The authors initiated a quality improvement project to identify barriers and enhance CR referral rates and participation. The team conducted a retrospective review of cardiac surgery patients from 2015 to 2022 at the Detroit Veterans Affairs. Phase 1 covered 2015-2017 (preintervention), phase 2 was the intervention period, and phase 3 covered 2018-2022 (postintervention). Appropriate CR referral was defined as within 6 months postevent. Referral rates and 1-year post-op hospitalization were assessed. Group 1 (2015-2017) had 54 male patients, 44% Black, 89% hypertensive, with a 22% CR referral rate. Group 2 (2018-2022) had 98 male patients, 64% Caucasian, mean age 73 years, with a 36% CR referral rate postintervention ( P = 0.0018). One-year hospitalization decreased from 26% to 13% ( P = 0.20). CR is still an underutilized tool. Provider education and complete funding of CR can improve referral rates and participation.
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Affiliation(s)
- Akash Gopal
- Wayne State University School of Medicine, Detroit, MI
| | - Ian Detroyer
- Wayne State University School of Medicine, Detroit, MI
- Department of Surgery, St. John Ascension, Detroit, MI
| | - Neiberg de Alcantara Lima
- Hartford HealthCare Heart and Vascular Institute, Hartford Hospital, Hartford, CT
- Department of Internal Medicine, Wayne State University, Detroit, MI
| | - Preeti Ramappa
- Department of Internal Medicine, Wayne State University, Detroit, MI
- Department of Cardiology, John D Dingell VA Medical Center, Detroit, MI
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Vilela EM, Almeida MC, Oliveira C, Nogueira T, Torres S, Teixeira M, Sampaio F, Ribeiro J, Oliveira M, Bettencourt N, Viamonte S, Fontes-Carvalho R. From the armchair to contemporary cardiac rehabilitation: the remarkable ongoing journey of exercise training in ischemic heart disease. Porto Biomed J 2024; 9:273. [PMID: 39563981 PMCID: PMC11573334 DOI: 10.1097/j.pbj.0000000000000273] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/11/2024] [Revised: 10/15/2024] [Accepted: 10/16/2024] [Indexed: 11/21/2024] Open
Abstract
Exercise is an important physiological activity with several health benefits. In the setting of ischemic heart disease (IHD), the view toward exercise has greatly evolved throughout the years, concurrently to several major advances in the management of this complex entity. Currently, exercise training has broad applications across the IHD continuum as a powerful tool in its overall management, being a core component of comprehensive cardiac rehabilitation programs. Beyond this, exercise has also been incorporated as an integral part of contemporary methodologies aiming to provide diagnostic and prognostic data, such as cardiopulmonary exercise stress testing or stress echocardiography. In this article, we provide a pragmatic overview concerning the role of exercise in IHD, with a focus on its incorporation in cardiac rehabilitation frameworks, while also discussing some of the challenges and unmet needs concerning these interventions.
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Affiliation(s)
- Eduardo M Vilela
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
- Department of Medicine, Faculty of Medicine, University of Porto, Porto, Portugal
| | - Marta Catarina Almeida
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
- Faculty of Medicine, Minho University, Braga, Portugal
| | - Cláudia Oliveira
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
| | - Teresa Nogueira
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
| | - Susana Torres
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
| | | | - Francisco Sampaio
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
- Cardiovascular Research Center (UniC@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
| | - José Ribeiro
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
| | - Marco Oliveira
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
| | - Nuno Bettencourt
- Cardiovascular Research Center (UniC@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
| | - Sofia Viamonte
- North Rehabilitation Centre, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
| | - Ricardo Fontes-Carvalho
- Cardiology Department, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, Portugal
- Cardiovascular Research Center (UniC@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
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Child CE, Ho LA, Lachant D, Gupta N, Moss J, Jones A, Krishna R, Holland AE, Han MK, McCarthy C, Ataya A, Baqir M, Dilling DF, Swigris J, Swenson ER, Brown MB. Unsupervised Exercise in Interstitial Lung Disease: A Delphi Study to Develop a Consensus Preparticipation Screening Tool for Lymphangioleiomyomatosis. Chest 2024; 166:1108-1123. [PMID: 39025205 PMCID: PMC11562656 DOI: 10.1016/j.chest.2024.06.3803] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/26/2024] [Revised: 06/13/2024] [Accepted: 06/25/2024] [Indexed: 07/20/2024] Open
Abstract
BACKGROUND Little research is available to provide practical guidance to health care providers for exercise preparticipation screening and referral of patients with interstitial lung diseases (ILDs), including lymphangioleiomyomatosis (LAM), to participate in remote, unsupervised exercise programs. RESEARCH QUESTION What exercise preparticipation screening steps are essential to determine whether a patient with LAM is medically appropriate to participate in a remote, unsupervised exercise program? STUDY DESIGN AND METHODS Sixteen experts in LAM and ILD participated in a two-round modified Delphi study, ranking their level of agreement for 10 statements related to unsupervised exercise training in LAM, with an a priori definition of consensus. Additionally, 60 patients with LAM completed a survey of the perceived risks and benefits of remote exercise training in LAM. RESULTS Seven of the 10 statements reached consensus among experts. Experts agreed that an in-person clinical exercise test is indicated to screen for exercise-induced hypoxemia and prescribe supplemental oxygen therapy as indicated prior to initiating a remote exercise program. Patients with recent pneumothorax should wait to start an exercise program for at least 4 weeks until after resolution of pneumothorax and clearance by a physician. Patients with high cardiovascular risk for event during exercise, severe resting pulmonary hypertension, or risk for falls may be more appropriate for referral to a rehabilitation center. A LAM-specific remote exercise preparticipation screening tool was developed from the consensus statements and agreed upon by the panelists. INTERPRETATION A modified Delphi study approach was useful to develop disease-specific recommendations for safety and preparticipation screening prior to unsupervised, remotely administered exercise in LAM. The primary product of this study is a clinical decision aid for providers to use when medically screening patients prior to participation in the newly launched LAMFit remote exercise program.
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Affiliation(s)
- Claire E Child
- Department of Rehabilitation Medicine, Division of Physical Therapy, University of Washington, Seattle, WA
| | - Lawrence A Ho
- Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA
| | | | | | - Joel Moss
- Critical Care Medicine and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
| | - Amanda Jones
- Critical Care Medicine and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
| | | | - Anne E Holland
- Monash University and Alfred Health, Melbourne, VIC, Australia; Institute for Breathing and Sleep, Melbourne, VIC, Australia
| | | | - Cormac McCarthy
- St. Vincent's University Hospital Dublin, Dublin, Ireland; University College Dublin, Dublin, Ireland
| | - Ali Ataya
- University of Florida, Gainesville, FL
| | | | - Daniel F Dilling
- Division of Pulmonary and Critical Care, Loyola University Chicago, Stritch School of Medicine, Maywood, IL
| | | | | | - Mary Beth Brown
- Department of Rehabilitation Medicine, Division of Physical Therapy, University of Washington, Seattle, WA.
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Brown TM, Pack QR, Aberegg E, Brewer LC, Ford YR, Forman DE, Gathright EC, Khadanga S, Ozemek C, Thomas RJ. Core Components of Cardiac Rehabilitation Programs: 2024 Update: A Scientific Statement From the American Heart Association and the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation 2024; 150:e328-e347. [PMID: 39315436 DOI: 10.1161/cir.0000000000001289] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 09/25/2024]
Abstract
The science of cardiac rehabilitation and the secondary prevention of cardiovascular disease has progressed substantially since the most recent American Heart Association and American Association of Cardiovascular and Pulmonary Rehabilitation update on the core components of cardiac rehabilitation and secondary prevention programs was published in 2007. In addition, the advent of new care models, including virtual and remote delivery of cardiac rehabilitation services, has expanded the ways that cardiac rehabilitation programs can reach patients. In this scientific statement, we update the scientific basis of the core components of patient assessment, nutritional counseling, weight management and body composition, cardiovascular disease and risk factor management, psychosocial management, aerobic exercise training, strength training, and physical activity counseling. In addition, in recognition that high-quality cardiac rehabilitation programs regularly monitor their processes and outcomes and engage in an ongoing process of quality improvement, we introduce a new core component of program quality. High-quality program performance will be essential to improve widely documented low enrollment and adherence rates and reduce health disparities in cardiac rehabilitation access.
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Grace SL, Ghanbari M, da Cruz MMA, Vanderlei LCM, Ghisi GLDM. Psychometric validation of the Cardiac Rehabilitation Barriers Scale Revised (CRBS-R) for hybrid delivery. BMJ Open 2024; 14:e090261. [PMID: 39414267 PMCID: PMC11481153 DOI: 10.1136/bmjopen-2024-090261] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 06/20/2024] [Accepted: 09/23/2024] [Indexed: 10/18/2024] Open
Abstract
OBJECTIVE To test the measurement properties of the revised version of the English Cardiac Rehabilitation Barriers Scale (CRBS-R), suitable for hybrid delivery, structural validity, internal reliability, as well as face, cross-cultural, construct and criterion validity were assessed. DESIGN Cross-sectional study, where participants completed an online survey via Qualtrics (2023-2024). SETTING Multicentre, with cardiac rehabilitation (CR) programmes recruiting patients globally; most patients stemmed from a hybrid programme in Iran and supervised programme in Brazil. PARTICIPANTS Participants include inpatients or outpatients with a cardiovascular diagnosis or procedure that is indicated for participation in CR. MEASURES In addition to sociodemographic and CR use items, the 21-item CRBS-R was administered. It assesses multilevel barriers and was revised based on a literature review. Responses range from 1 to 5, with higher scores indicating greater barriers. RESULTS 235 patients participated from all 6 WHO regions. Items were rated as highly applicable, and open-ended responses revealing no key barriers were omitted, supporting face and cross-cultural validity. Cronbach's α for the total CRBS-R was 0.82. Principal components analysis resulted in the extraction of 4 components, which collectively accounted for 60.5% of the variance and were all internally consistent. Construct validity was supported by associations of total CRBS scores with work status (p=0.04), exercise history (p=0.01) and social support (p=0.03). Total CRBS-R scores were significantly lower in patients who were referred and enrolled versus those who were not (both p≤0.01), confirming criterion validity. CONCLUSIONS The CRBS-R is a reliable and valid scale comprising four subscales, applicable to hybrid CR across diverse settings. It can serve as a valuable tool to support identification of patient's CR barriers, to optimise secondary prevention utilisation globally.
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Affiliation(s)
- Sherry L Grace
- Faculty of Health, York University, Toronto, Ontario, Canada
- KITE Research Institute, University Health Network, Toronto, Ontario, Canada
| | - Mahdieh Ghanbari
- Yazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
| | | | | | - Gabriela Lima de Melo Ghisi
- KITE Research Institute, University Health Network, Toronto, Ontario, Canada
- Department pf Physical Therapy, University of Toronto, Toronto, Ontario, Canada
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Choi HI, Lee SJ, Choi JD, Kim G, Lee YS, Lee JY. Efficacy of Wearable Single-Lead ECG Monitoring during Exercise Stress Testing: A Comparative Study. SENSORS (BASEL, SWITZERLAND) 2024; 24:6394. [PMID: 39409434 PMCID: PMC11479017 DOI: 10.3390/s24196394] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 08/13/2024] [Revised: 09/27/2024] [Accepted: 09/28/2024] [Indexed: 10/20/2024]
Abstract
BACKGROUND AND OBJECTIVES Few comparative studies have evaluated wearable single-lead electrocardiogram (ECG) devices and standard multi-lead ECG devices during exercise testing. This study aimed to validate the accuracy of a wearable single-lead ECG monitor for recording heart rate (HR) metrics during graded exercise tests (GXTs). METHODS A cohort of 50 patients at a tertiary hospital underwent GXT while simultaneously being equipped with wearable single- and conventional multi-lead ECGs. The concordance between these modalities was quantified using the intraclass correlation coefficient and Bland-Altman plot analysis. RESULTS The minimum and average HR readings between the devices were generally consistent. Parameters such as ventricular ectopic beats and supraventricular ectopic beats showed strong agreement. However, the agreement for the Total QRS and Maximum RR was not sufficient. HR measurements across different stages of the exercise test showed sufficient agreement. Although not statistically significant, the standard multi-lead ECG devices exhibited higher noise levels compared to the wearable single-lead ECG devices. CONCLUSIONS Wearable single-lead ECG devices can reliably monitor HR and detect abnormal beats across a spectrum of exercise intensities, offering a viable alternative to traditional multi-lead systems.
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Affiliation(s)
- Hyo-In Choi
- Division of Cardiology, Department of Internal Medicine, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul 03181, Republic of Korea; (H.-I.C.); (S.J.L.)
| | - Seung Jae Lee
- Division of Cardiology, Department of Internal Medicine, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul 03181, Republic of Korea; (H.-I.C.); (S.J.L.)
| | - Jong Doo Choi
- Seers Technology Co., Ltd., Seongnam-si 13558, Republic of Korea; (J.D.C.); (G.K.); (Y.-S.L.)
| | - GyungChul Kim
- Seers Technology Co., Ltd., Seongnam-si 13558, Republic of Korea; (J.D.C.); (G.K.); (Y.-S.L.)
| | - Young-Shin Lee
- Seers Technology Co., Ltd., Seongnam-si 13558, Republic of Korea; (J.D.C.); (G.K.); (Y.-S.L.)
| | - Jong-Young Lee
- Division of Cardiology, Department of Internal Medicine, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul 03181, Republic of Korea; (H.-I.C.); (S.J.L.)
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Li R, Wang M, Chen S, Zhang L. Comparative efficacy and adherence of telehealth cardiac rehabilitation interventions for patients with cardiovascular disease: A systematic review and network meta-analysis. Int J Nurs Stud 2024; 158:104845. [PMID: 39032245 DOI: 10.1016/j.ijnurstu.2024.104845] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/08/2023] [Revised: 06/19/2024] [Accepted: 06/20/2024] [Indexed: 07/23/2024]
Abstract
BACKGROUND Traditional center-based cardiac rehabilitation had low adherence rates. With the increasing utilization of digital technology in healthcare services, telehealth can overcome common barriers to improve adherence, and some telehealth interventions have been proven safe and effective. However, it remains unclear which telehealth intervention types can maximize the efficacy and adherence for cardiac rehabilitation. OBJECTIVE To compare the effect of different types of telehealth interventions on the efficacy and adherence of patients with cardiovascular disease in cardiac rehabilitation. DESIGN Systematic review and network meta-analysis. METHODS We systematically searched PubMed, Cochrane Central Register of Controlled Trials, Web of Science, CINAHL, ProQuest, Scopus, and Embase databases for randomized controlled trials of telehealth cardiac rehabilitation for cardiovascular disease patients from January 2013 to March 2024. The primary outcomes were peak oxygen uptake (VO2 peak) and adherence. Secondary outcomes included 6-minute walking distance, moderate-to-vigorous intensity physical activity, depression, self-reported quality of life, and patient satisfaction. The study protocol has been registered on PROSPERO (ID: CRD42023459643). RESULTS This network meta-analysis included 46 randomized controlled trials. The results indicated that telehealth cardiac rehabilitation improved VO2 peak, 6-minute walking distance, moderate-to-vigorous intensity physical activity, and adherence. The surface under the cumulative ranking curve (SUCRA) results showed that the Wearable Devices + Smartphone Applications (SUCRA = 86.8 %, mean rank = 1.7) was the most effective telehealth intervention for improving VO2 peak. The Smartphone Applications + Instant Communication Tools (SUCRA = 74.2 %, mean rank = 2.6) was the most effective telehealth intervention for promoting adherence. CONCLUSIONS Combining two or more types of telehealth interventions was found to be effective. Future efforts should prioritize conducting high-quality randomized controlled trials to identify more effective combinations with traditional cardiac rehabilitation.
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Affiliation(s)
- Ruru Li
- The First School of Medicine, Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China
| | - Miao Wang
- The School of Nursing, Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China
| | - Shuoshuo Chen
- The First School of Medicine, Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China
| | - Liqing Zhang
- The Department of Nursing, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
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Bates BA, Enzan N, Tohyama T, Gandhi P, Matsushima S, Tsutsui H, Setoguchi S, Ide T. Management and outcomes of heart failure hospitalization among older adults in the United States and Japan. ESC Heart Fail 2024; 11:3395-3405. [PMID: 38978406 PMCID: PMC11424315 DOI: 10.1002/ehf2.14873] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/09/2023] [Revised: 03/11/2024] [Accepted: 05/12/2024] [Indexed: 07/10/2024] Open
Abstract
AIMS Despite advances in therapies, the disease burden of heart failure (HF) has been rising globally. International comparisons of HF management and outcomes may reveal care patterns that improve outcomes. Accordingly, we examined clinical management and patient outcomes in older adults hospitalized for acute HF in the United States (US) and Japan. METHODS We identified patients aged >65 who were hospitalized for HF in 2013 using US Medicare data and the Japanese Registry of Acute Decompensated Heart Failure (JROADHF). We described patient characteristics, management, and healthcare utilization and compared outcomes using multivariable Cox regression during and after HF hospitalization. RESULTS Among 11 193 Japanese and 120 289 US patients, age and sex distributions were similar, but US patients had higher comorbidity rates. The length of stay was longer in Japan (median 18 vs. 5 days). While Medicare patients had higher use of implantable cardioverter defibrillator or cardiac resynchronization therapy during hospitalization (1.32% vs. 0.6%), Japanese patients were more likely to receive cardiovascular medications at discharge and to undergo cardiac rehabilitation within 3 months of HF admission (31% vs. 1.6%). Physician follow-up within 30 days was higher in Japan (77% vs. 57%). Cardiovascular readmission, cardiovascular mortality and all-cause mortality were 2.1-3.7 times higher in the US patients. The per-day cost of hospitalization was lower in Japan ($516 vs. $1323). CONCLUSIONS We observed notable differences in the management, outcomes and costs of HF hospitalization between the US and Japan. Large differences in length of hospitalization, cardiac rehabilitation rate and outcomes warrant further research to determine the optimal length of stay and assess the benefits of inpatient cardiac rehabilitation to reduce rehospitalization and mortality.
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Affiliation(s)
- Benjamin A. Bates
- Institute For Health, Healthcare Policy, and Aging ResearchRutgers UniversityNew BrunswickNew JerseyUSA
- Department of MedicineRutgers Robert Wood Johnson Medical SchoolNew BrunswickNew JerseyUSA
| | - Nobuyuki Enzan
- Department of Cardiovascular Medicine, Faculty of Medical SciencesKyushu UniversityFukuokaJapan
- Division of Cardiovascular Medicine, Research Institute of AngiocardiologyKyushu UniversityFukuokaJapan
| | - Takeshi Tohyama
- Center for Clinical and Translational ResearchKyushu University HospitalFukuokaJapan
| | - Poonam Gandhi
- Institute For Health, Healthcare Policy, and Aging ResearchRutgers UniversityNew BrunswickNew JerseyUSA
| | - Shouji Matsushima
- Department of Cardiovascular Medicine, Faculty of Medical SciencesKyushu UniversityFukuokaJapan
- Division of Cardiovascular Medicine, Research Institute of AngiocardiologyKyushu UniversityFukuokaJapan
| | - Hiroyuki Tsutsui
- Department of Cardiovascular Medicine, Faculty of Medical SciencesKyushu UniversityFukuokaJapan
- Division of Cardiovascular Medicine, Research Institute of AngiocardiologyKyushu UniversityFukuokaJapan
| | - Soko Setoguchi
- Institute For Health, Healthcare Policy, and Aging ResearchRutgers UniversityNew BrunswickNew JerseyUSA
- Department of MedicineRutgers Robert Wood Johnson Medical SchoolNew BrunswickNew JerseyUSA
| | - Tomomi Ide
- Department of Cardiovascular Medicine, Faculty of Medical SciencesKyushu UniversityFukuokaJapan
- Division of Cardiovascular Medicine, Research Institute of AngiocardiologyKyushu UniversityFukuokaJapan
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Bilbrey T, Martin J, Zhou W, Bai C, Vaswani N, Shah R, Chokshi S, Chen X, Bhusri S, Niemi S, Meng H, Lei Z. A Dual-Modality Home-Based Cardiac Rehabilitation Program for Adults With Cardiovascular Disease: Single-Arm Remote Clinical Trial. JMIR Mhealth Uhealth 2024; 12:e59098. [PMID: 39150858 PMCID: PMC11480683 DOI: 10.2196/59098] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/08/2024] [Revised: 07/20/2024] [Accepted: 08/12/2024] [Indexed: 08/18/2024] Open
Abstract
BACKGROUND Cardiac rehabilitation (CR) is a safe, effective intervention for individuals with cardiovascular disease (CVD). However, a majority of eligible patients do not complete CR. Growing evidence suggests that home-based cardiac rehabilitation (HBCR) programs are comparable in effectiveness and safety with traditional center-based programs. More research is needed to explore different ways to deliver HBCR programs to patients with CVD. OBJECTIVE We aimed to assess the feasibility and impact of a digital HBCR program (RecoveryPlus.Health) that integrates both telehealth and mHealth modalities on functional exercise capacity, resting heart rate, and quality of life among adults with CVD. METHODS This 12-week prospective, single-arm remote clinical trial used a within-subject design. We recruited adults with CVD (aged ≥40 years) from the community with a CR-eligible diagnosis (stable angina pectoris, myocardial infarction, and heart failure) between May and August 2023. All enrolled patients referred to the RPH clinic in Roanoke, Texas, were included. The care team provided guideline-concordant CR services to study participants via two modalities: (1) a synchronous telehealth exercise training through videoconferencing; and (2) an asynchronous mobile health (mHealth) coaching app (RPH app). Baseline intake survey, electronic health record, and app log data were used to extract individual characteristics, care processes, and platform engagement data. Feasibility was measured by program completion rate and CR service use. Efficacy was measured by changes in the 6-minute walk test, resting heart rate, and quality of life (12-Item Short-Form Health Survey) before and after the 12-week program. Paired t tests were used to examine pre- and postintervention changes in the outcome variables. RESULTS In total, 162 met the inclusion criteria and 75 (46.3%) consented and were enrolled (mean age 64, SD 10.30 years; male: n=37, 49%; White: n=46, 61%). Heart failure was the most common diagnosis (37/75, 49%). In total, 62/75 (83%) participants completed the 12-week study and used the telehealth modality with 9.63 (SD 3.33) sessions completed, and 59/75 (79%) used the mHealth modality with 10.97 (SD 11.70) sessions completed. Post intervention, 50/62 (81%) participants' performance in the 6-minute walk test had improved, with an average improvement of 40 (SD 63.39) m (95% CI 25.6-57.1). The average 12-Item Short-Form Health Survey's physical and mental summary scores improved by 2.7 (SD 6.47) points (95% CI 1.1-4.3) and 2.2 (SD 9.09) points (95% CI 0.1-4.5), respectively. There were no changes in resting heart rate and no exercise-related adverse events were reported. CONCLUSIONS The RecoveryPlus.Health digital HBCR program showed feasibility and efficacy in a group of nationally recruited patients with CVD. The findings add to the evidence that a telehealth and mHealth dual-modality HBCR program may be a promising approach to overcome some of the main barriers to improving CR access in the United States. TRIAL REGISTRATION ClinicalTrials.gov NCT05804500; https://clinicaltrials.gov/search?cond=NCT05804500.
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Affiliation(s)
- Tim Bilbrey
- RecoveryPlus.Health, Inc, New York, NY, United States
| | - Jenny Martin
- RecoveryPlus.Health, Inc, New York, NY, United States
| | - Wen Zhou
- RecoveryPlus.Health, Inc, New York, NY, United States
| | - Changhao Bai
- RecoveryPlus.Health, Inc, New York, NY, United States
| | - Nitin Vaswani
- Node.Health Foundation, Wilmington, DE, United States
| | - Rishab Shah
- Node.Health Foundation, Wilmington, DE, United States
| | - Sara Chokshi
- Node.Health Foundation, Wilmington, DE, United States
| | - Xi Chen
- RecoveryPlus.Health, Inc, New York, NY, United States
| | - Satjit Bhusri
- Upper East Side Cardiology PLLC, New York, NY, United States
| | - Samantha Niemi
- McCormick School of Engineering, Northwestern University, Chicago, IL, United States
| | - Hongdao Meng
- School of Aging Studies, University of South Florida, Tampa, FL, United States
| | - Zhen Lei
- RecoveryPlus.Health, Inc, New York, NY, United States
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Mirzaei Najmabadi A, Rahimi MS, Riahi SM, Kazemi T. Cardiac rehabilitation is necessary for patients: Providing experiences from the launch of cardiac rehabilitation in a deprived province in Iran. JOURNAL OF RESEARCH IN MEDICAL SCIENCES : THE OFFICIAL JOURNAL OF ISFAHAN UNIVERSITY OF MEDICAL SCIENCES 2024; 29:57. [PMID: 39629032 PMCID: PMC11613981 DOI: 10.4103/jrms.jrms_687_23] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 10/12/2023] [Revised: 02/14/2024] [Accepted: 02/28/2024] [Indexed: 12/06/2024]
Affiliation(s)
- A Mirzaei Najmabadi
- School of Medicine, Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran
| | - Maryam Sadat Rahimi
- Department of Surgery, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
| | - Seyed Mohammad Riahi
- Department of Community Medicine, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
| | - Toba Kazemi
- Department of Cardiology, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
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Redfern J, Gallagher R, Maiorana A, Candelaria D, Hollings M, Gauci S, O'Neil A, Chaseling GK, Zhang L, Thomas EE, Ghisi GLM, Gibson I, Hyun K, Beatty A, Briffa T, Taylor RS, Arena R, Jennings C, Wood D, Grace SL. Cardiac rehabilitation and secondary prevention of CVD: time to think about cardiovascular health rather than rehabilitation. NPJ CARDIOVASCULAR HEALTH 2024; 1:22. [PMID: 39359645 PMCID: PMC11442299 DOI: 10.1038/s44325-024-00017-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 04/06/2024] [Accepted: 07/25/2024] [Indexed: 10/04/2024]
Abstract
During the past century, there have been major developments in the medical and surgical treatment of cardiovascular disease (CVD). These advancements have resulted in more people surviving initial events and having reduced length of stay in hospital; consequently, there is an increasing number of people in need of ongoing and lifelong cardiovascular risk management. The physical and emotional effects of living with CVD are ongoing with broad challenges ranging from the individual to system level. However, post-discharge care of people with coronary disease continues to follow a 50-year-old cardiac rehabilitation model which focuses on the sub-acute phase and is of a finite in duration. The aim of this paper is to consider the concept of supporting survivors to live well with CVD rather than 'rehabilitating' them and propose factors for consideration in reframing secondary prevention towards optimizing cardiovascular health. We discuss deeply-held potential considerations and challenges associated with the concept of supporting survivors achieve optimal cardiovascular health and live well with CVD rather than 'rehabilitating' them. We propose the concept of 5 x P's for reframing traditional cardiac rehabilitation towards the concept of cardiovascular health for survivors beyond 'rehabilitation'. These include the need for personalization, processes, patient-centered care, parlance, and partnership. Taken together, consideration of challenges at the systems and population level will ultimately improve engagement with secondary prevention as well as outcomes for all people who need it.
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Affiliation(s)
- Julie Redfern
- Institute for Evidence-Based Healthcare, Bond University, Gold Coast, NSW Australia
- Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia
| | - Robyn Gallagher
- Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia
| | - Andrew Maiorana
- Curtin School of Allied Health, Curtin University, Bentley, WA Australia
- Allied Health Department, Fiona Stanley Hospital, Murdoch, WA Australia
| | - Dion Candelaria
- Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia
| | - Matthew Hollings
- School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia
| | - Sarah Gauci
- Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC Australia
| | - Adrienne O'Neil
- Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC Australia
| | - Georgia K Chaseling
- Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia
| | - Ling Zhang
- Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia
| | - Emma E Thomas
- Centre for Online Health, Centre for Health Services Research, The University of Queensland, Brisbane, QLD Australia
| | | | - Irene Gibson
- School of Medicine, University of Galway, Galway, Republic of Ireland
| | - Karice Hyun
- School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia
- Cardiology Department, Concord Hospital, ANZAC Research Institute, Concord, NSW Australia
| | - Alexis Beatty
- Alexis L Beatty, Departments of Epidemiology & Biostatistics and Medicine, University of California, California, USA
| | - Tom Briffa
- University of Western Australia, Crawley, WA Australia
| | - Rod S Taylor
- School of Health and Well Being, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland UK
| | - Ross Arena
- Department of Physical Therapy, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL USA
| | - Catriona Jennings
- National Institute for Prevention and Cardiovascular Health NIPC and University of Galway, Galway, Republic of Ireland
| | - David Wood
- National Institute for Prevention and Cardiovascular Health NIPC and University of Galway, Galway, Republic of Ireland
| | - Sherry L Grace
- Faculty of Health, York University, Toronto, ON Canada
- KITE & Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, ON Canada
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Svenningsen A, Söderström S, Bucher Sandbakk S, Gullestad L, Bønaa KH, Wisløff U, Hollekim-Strand SM. Mind the intention-behavior gap: a qualitative study of post-myocardial infarction patients' beliefs and experiences with long-term supervised and self-monitored physical exercise. BMC Sports Sci Med Rehabil 2024; 16:204. [PMID: 39334432 PMCID: PMC11437989 DOI: 10.1186/s13102-024-00987-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/04/2024] [Accepted: 09/10/2024] [Indexed: 09/30/2024]
Abstract
BACKGROUND Many post-myocardial infarction (MI) patients struggle with physical activity behavior change (BC) for life-long secondary prevention. There is limited knowledge about factors influencing long-term physical activity BC among post-MI patients. This qualitative study aimed to explore the beliefs and experiences related to post-MI patients' physical activity BC process following a year's participation in a supervised and self-monitored exercise program: the Norwegian Trial of Physical Exercise After MI (NorEx). METHODS We conducted a qualitative study, performing in-depth semi-structured interviews with a randomly selected sample of NorEx participants when they were scheduled for cardiopulmonary exercise testing after one year of participation. Interviews were transcribed verbatim and the data was analyzed by applying reflexive thematic analysis. RESULTS Seventeen participants (n = 4 female [24%]; median age, 61 years; median time since index MI, 4 years) were recruited and interviewed once. Analysis resulted in four main themes (nine sub-themes): (1) Personal responsibility to exercise (Exercise is safe, Health benefits, Habitual exercise); (2) Peer social support for a sense of safety and belonging (Social exercise, Supervision is preferred); (3) Research participation transformed exercise beliefs (High-intensity exercise is superior, Personal Activity Intelligence (PAI) promotes exercise adherence); and (4) Mind the intention-behavior gap (Initial anxiety, Lack of continued follow-up). CONCLUSIONS Several participants reported that they were able to maintain exercise BC during a year's participation in NorEx. Nevertheless, a perceived lack of continued and individualized follow-up made some participants struggle with motivation and self-regulation, leading to an intention-behavior gap. Therefore, our findings suggest there is a need for individualized and continued social support and supervision from health and exercise professionals to maintain long-term exercise BC for secondary prevention among post-MI patients. TRIAL REGISTRATION The NorEx study has been registered at ClinicalTrials.gov (NCT04617639, registration date 2020-10-21).
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Affiliation(s)
- Alexander Svenningsen
- Faculty of Medicine and Health Sciences, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), 8905, Trondheim, 7491, Norway.
| | - Sylvia Söderström
- Department of Neuromedicine and Movement Science, NTNU, Trondheim, Norway
| | | | - Lars Gullestad
- Institute of Clinical Medicine, Department of Cardiology, University of Oslo, Oslo, Norway
| | - Kaare Harald Bønaa
- Clinic for Heart Disease, St. Olav University Hospital, Trondheim, Norway
| | - Ulrik Wisløff
- Department of Circulation and Medical Imaging, NTNU, Trondheim, Norway
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Gallo G, Volterrani M, Fini M, Sposato B, Autore C, Tocci G, Volpe M. Position Statement of the Italian Society of Cardiovascular Prevention (SIPREC) and Italian Heart Failure Association (ITAHFA) on Cardiac Rehabilitation and Protection Programs as a Cornerstone of Secondary Prevention after Myocardial Infarction or Revascularization. High Blood Press Cardiovasc Prev 2024; 31:417-423. [PMID: 39060868 DOI: 10.1007/s40292-024-00663-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/24/2024] [Accepted: 07/12/2024] [Indexed: 07/28/2024] Open
Abstract
Despite the remarkable and progressive advances made in the prevention and management of cardiovascular diseases, the recurrence of cardiovascular events remains unacceptably elevated with a notable size of the residual risk. Indeed, in patients who suffered from myocardial infarction or who underwent percutaneous or surgical myocardial revascularization, life-style changes and optimized pharmacological therapy with antiplatelet drugs, lipid lowering agents, beta-blockers, renin angiotensin system inhibitors and antidiabetic drugs, when appropriate, are systematically prescribed but they might be insufficient to protect from further events. In such a context, an increasing body of evidence supports the benefits of cardiac rehabilitation (CR) in the setting of secondary cardiovascular prevention, consisting in the reduction of myocardial oxygen demands, in the inhibition of atherosclerotic plaque progression and in an improvement of exercise performance, quality of life and survival. However, prescription and implementation of CR programs is still not sufficiently considered.The aim of this position paper of the Italian Society of Cardiovascular Prevention (SIPREC) and of the Italian Heart Failure Association (ITAHFA) is to examine the reasons of the insufficient use of this strategy in clinical practice and to propose some feasible solutions to overcome this clinical gap.
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Affiliation(s)
- Giovanna Gallo
- Department of Clinical and Molecular Medicine, Sapienza University of Rome, Via di Grottarossa 1035-1039, Rome, 00189, Italy
| | | | | | | | - Camillo Autore
- Cardio-Pulmonary Department, San Raffaele Cassino, Cassino (FR), 03043, Italy
| | - Giuliano Tocci
- Department of Clinical and Molecular Medicine, Sapienza University of Rome, Via di Grottarossa 1035-1039, Rome, 00189, Italy
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Vilela EM, Bento L, Oliveira L, Abreu A, Dores H, Teixeira M, Mendes M, Fontes P, Fontes-Carvalho R, Pereira H, Gonçalves L. Training and attitudes concerning cardiac rehabilitation in Portugal: A national survey of physician members of the Portuguese Society of Cardiology. Rev Port Cardiol 2024; 43:487-496. [PMID: 38460749 DOI: 10.1016/j.repc.2023.12.009] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/12/2023] [Accepted: 12/22/2023] [Indexed: 03/11/2024] Open
Abstract
INTRODUCTION AND OBJECTIVES Cardiac rehabilitation (CR) is a central component in the management of cardiovascular disease. While its potential benefits have been extensively explored and confirmed, its implementation is still suboptimal, due to various possible barriers. This study aimed to assess training and attitudes concerning CR among physicians in a Portuguese setting. METHODS An online questionnaire structured in three parts (participant characteristics, training and attitudes concerning CR, and a brief general knowledge assessment) was developed and sent to members of the Portuguese Society of Cardiology. The study population encompassed physicians with a medical specialty or residents from the third year onward of a specialty program. RESULTS A total of 97 individuals (57.7% male, 61.9% aged ≤50 years) presented valid answers. CR was available at the workplace of 54.6% of participants. Most of them considered that the time allocated to CR training during residency was inadequate, and thought that more time was needed for this purpose. Most had not dedicated (or intended to dedicate) time for CR training, with lack of time being the most frequently attributed reason. In terms of referral, a substantial proportion of subjects did not refer patients, with lack of CR centers and human resources being the most frequent reasons. CONCLUSIONS This survey provides contemporary data on CR training and attitudes, highlighting areas of potential improvement, such as time allocated to training in this area. These results could provide a useful pragmatic framework for optimization of training and awareness in this pivotal field of cardiovascular medicine.
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Affiliation(s)
- Eduardo M Vilela
- Cardiology Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
| | - Luísa Bento
- Cardiology Department, Hospital Garcia de Orta, Portugal
| | - Luís Oliveira
- Cardiology Department, Centro Hospitalar Universitário Cova da Beira, Covilhã, Portugal
| | - Ana Abreu
- Serviço de Cardiologia, Hospital Universitário de Santa Maria/Centro Hospitalar Universitário Lisboa Norte (CHULN), Lisboa, Portugal; Centro Académico de Medicina de Lisboa (CAML), Centro Cardiovascular da Universidade de Lisboa (CCUL), Lisboa, Portugal; Instituto de Saúde Ambiental (ISAMB), Instituto Medicina Preventiva e Saúde Pública (IMPSP), Instituto de Medicina Nuclear (IMN), Faculdade de Medicina da Universidade de Lisboa (FMUL), Lisboa, Portugal
| | - Hélder Dores
- Cardiology Department, Hospital da Luz, Lisboa, Portugal; NOVA Medical School, Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisbon, Portugal; CHRC, NOVA Medical School, Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisbon, Portugal
| | - Madalena Teixeira
- Cardiology Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal
| | - Miguel Mendes
- Cardiology Department, Centro Hospitalar de Lisboa Ocidental - Hospital de Santa Cruz, Carnaxide, Portugal
| | - Paulo Fontes
- Cardiology Department, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal
| | - Ricardo Fontes-Carvalho
- Cardiology Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal; Cardiovascular Research Center (UniC@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
| | - Hélder Pereira
- Cardiology Department, Hospital Garcia de Orta, Portugal; Faculty of Medicine, University of Lisbon, Lisboa, Portugal
| | - Lino Gonçalves
- Cardiology Department, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal
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Mahfouz Khalil MI, El-Monshed AH, Shaala RS, El-Sherif SM, Mousa EFS. Home-based transitional cardiac telerehabilitation in older adults post coronary artery bypass grafting: A randomized controlled trial. Geriatr Nurs 2024; 59:139-149. [PMID: 39002504 DOI: 10.1016/j.gerinurse.2024.06.044] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/29/2024] [Revised: 06/09/2024] [Accepted: 06/27/2024] [Indexed: 07/15/2024]
Abstract
This randomized controlled trial evaluated the effectiveness of a 12-week home-based transitional cardiac telerehabilitation (Hb-T-CTR) program on health-related quality-of-life and therapeutic self-care in older adults' post-Coronary Artery Bypass Grafting (CABG). The intervention group (n = 57) underwent Hb-T-CTR, incorporating preoperative counseling, postoperative education, a culturally adapted video, home visits, and telephone counseling, while the control group (n = 61) received standard care. Using the Coronary Revascularization Outcome Questionnaire and the Sidani Doran Therapeutic Self-Care Measure, data were collected at three time points. Results showed significant improvements in overall scores for both health-related quality of life (t1=3.386, P = 0.001; t2=4.224, P < 0.001) and therapeutic self-care (t1=7.104, P < 0.001; t2=4.242, P < 0.001) in the intervention group compared to controls. This telehealth approach provides convenient and accessible rehabilitation services for older adults' post-CABG and highlights the importance of integrating Hb-T-CTR into routine care for personalized rehabilitation. This study underscores the potential of telehealth tools in overcoming barriers and enhancing patient-centered interventions.
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Affiliation(s)
| | - Ahmed Hashem El-Monshed
- Department of Nursing, College of Health and Sport Sciences, University of Bahrain, Manama, Bahrain; Department of Psychiatric and Mental Health Nursing, Faculty of Nursing-Mansoura University, Egypt.
| | - Reem Said Shaala
- Department of Internal Medicine, Geriatric Unit, Faculty of Medicine, Alexandria University, Egypt
| | - Sherine Mahmoud El-Sherif
- Department of Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Alexandria University, Egypt
| | - Enas Fouad Sayed Mousa
- Department of Geriatric Medicine and Gerontology, Faculty of Medicine, Helwan University, Egypt
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Jansson AK, Schumacher TL, Kocanda L, Whatnall M, Fenwick M, Betts D, Bauman A, Kerr J, Duncan MJ, Collins CE, Boyle A, Inder KJ, Plotnikoff RC. A Systematic Review of the Completion of Cardiac Rehabilitation Programs for Adults Aged 18-50 Years. J Cardiopulm Rehabil Prev 2024; 44:E30-E51. [PMID: 39185913 DOI: 10.1097/hcr.0000000000000881] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 08/27/2024]
Abstract
OBJECTIVE To perform a systematic review of completion rates of cardiac rehabilitation (CR) in adults aged 18 to 50 yr and describe how core components were reported, measured, and tailored to those under 50 yr. REVIEW METHODS Database search of MEDLINE, Embase, Emcare, PsycINFO, CINAHL, Scopus, and the Cochrane Library based on keywords, including articles from January 1, 1990. The last search was performed on April 21, 2023. Following the Preferred Reporting Items for Systematic Review and Meta-Analyses protocol, eligible articles contained adults (aged between 18 and 50 yr) who had participated in a CR program. SUMMARY Out of the articles screened (n = 24,517), 33 reports across 31 independent studies were considered eligible (n = 1958 patients aged ≤50 yr). Cardiac rehabilitation completion rates ranged from 64% to 100%; however, only 5 studies presented a completion rate definition. The length of the program ranged from 7 d to 20 wk, with most (65%) ranging between 6 and 12 wk. While the studies included in this systematic review indicated relatively high rates of completing CR, these are likely to overrepresent the true completion rates as few definitions were provided that could be compared to completion rates used in clinical practice. This systematic review also found that all interventions prescribed exercise (eg, aerobic alone or combined with resistance training or yoga) but had very limited inclusion or description of other integral components of CR (eg, initial assessment and smoking cessation) or how they were assessed and individualized to meet the needs of younger attendees.
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Affiliation(s)
- Anna K Jansson
- Author Affiliations: Centre for Active Living and Learning, School of Education, The University of Newcastle, Newcastle, New South Wales, Australia (Drs Jansson and Plotnikoff); Active Living Research Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia (Dr Jansson, Mr Fenwick, and Drs Duncan and Plotnikoff); Department of Rural Health, The University of Newcastle, Tamworth, New South Wales, Australia (Drs Schumacher and Kocanda); School of Health Science, College of Health and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia (Drs Whatnall and Collins); Food and Nutrition Research Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia (Drs Kocanda, Whatnall, and Collins); School of Medicine and Public Health, The University of Newcastle, Newcastle, New South Wales, Australia (Mr Fenwick and Drs Duncan and Boyle); Cancer Council NSW, Sydney, New South Wales, Australia (Mrs Betts); School of Public Health, University of Sydney, Sydney, New South Wales, Australia (Dr Bauman); Hunter New England Health, Newcastle, New South Wales, Australia (Ms Kerr and Dr Inder); and School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (Dr Inder)
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Ghisi GLM, Bomtempo APD, Gonzalez NF, Reyes GP, Anchique CV. Evaluating the Clinical Effectiveness of Cardiac Rehabilitation among Patients of Very Low Socioeconomic Status Living in Colombia. J Cardiovasc Dev Dis 2024; 11:255. [PMID: 39330313 PMCID: PMC11432289 DOI: 10.3390/jcdd11090255] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/22/2024] [Revised: 08/19/2024] [Accepted: 08/20/2024] [Indexed: 09/28/2024] Open
Abstract
Cardiovascular disease (CVD) poses a significant health burden, particularly among individuals of low socioeconomic status (SES) in low- and middle-income countries (LMICs). This study evaluates the clinical effectiveness of cardiac rehabilitation (CR) in addressing CVD outcomes among very low-SES patients in Colombia. Data from participants enrolled in a CR program in Colombia between 2022 and 2023 were analyzed retrospectively. Measures included heart-healthy behaviors, physical/psychological outcomes, and quality of life assessed at 18, 36, and 60 sessions. Significant improvements were observed in exercise capacity, psychological well-being, and quality of life metrics throughout the CR program. However, barriers to CR attendance and the critical need for expanded program availability remain evident, particularly in LMIC settings like Colombia. In conclusion, structured CR programs demonstrate substantial benefits for very low-SES individuals in a LMIC country, highlighting the urgent need for increased program accessibility and equitable healthcare provision to optimize cardiovascular health outcomes.
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Affiliation(s)
- Gabriela L. M. Ghisi
- KITE Research Institute, University Health Network, University of Toronto, Toronto, ON M4G 1R7, Canada
| | - Ana Paula Delgado Bomtempo
- Graduate Program in Physical Education, Faculty of Physical Education and Sports, Federal University of Juiz de Fora, Juiz de Fora 36036-900, Brazil;
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Gibson I, Kerins C, Foley L, Hynes L, Byrne M, Murphy AW, Reardon CM, McEvoy JW, Meade O. Factors influencing implementation of digital cardiac rehabilitation: A qualitative analysis of health workers perspectives. HRB Open Res 2024; 7:50. [PMID: 39391821 PMCID: PMC11464961 DOI: 10.12688/hrbopenres.13929.1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 07/18/2024] [Indexed: 10/12/2024] Open
Abstract
Background Despite growing evidence for the effectiveness of digital cardiac rehabilitation (CR) uptake of this technology remains low. Understanding the factors that influence implementation of digital CR in clinical practice is a growing area of research. The aim of this nested qualitative study was to explore health worker perspectives on factors influencing implementation of a digital CR programme. Methods Using convenience sampling, semi-structured interviews were conducted with health workers, including health care professionals (nurses, dietitians, physiotherapists) and those in administrative and managerial roles who were involved in delivering and referring patients to Croí MySláinte, a 12-week digital CR intervention delivered during the Coronavirus 2019 pandemic. The updated Consolidated Framework for Implementation Research (CFIR) guided data collection and framework analysis. Results Interviews were conducted with 14 health workers. Factors influencing implementation of Croí MySláinte were multiple, with some operating independently and others in combination. They related to: (i) characteristics of individuals (e.g., senior leadership support, commitment and motivation of Health workers to meet patient needs, technical capability, workload and perceived fit with role); (ii) features of the programme (e.g., accessibility and convenience for patients, the digital platform, patient self- monitoring tools, the multidisciplinary team and core components); (iii) the external environment (e.g., partnership and connections between organisations, broadband and COVID-19); (iv) the internal environment (e.g., organisational culture, teamwork, resources including funding, digital infrastructure and staffing); and (v) the implementation process (e.g., engaging patients through provision of technical support). Conclusion The study findings suggest that factors influencing implementation of digital CR operate at multiple levels. Therefore, multi-level implementation strategies are required if the true potential of digital health in improving equitable cardiac rehabilitation access, participation and patient outcomes is to be realised.
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Affiliation(s)
- Irene Gibson
- School of Medicine, University of Galway, Galway, County Galway, Ireland
- National Institute for Prevention and Cardiovascular Health, Galway, Ireland
| | - Claire Kerins
- Health Promotion Research Centre, University of Galway, Galway, County Galway, Ireland
| | - Louise Foley
- School of Allied Health, University of Limerick, Limerick, County Limerick, Ireland
| | - Lisa Hynes
- Croí, West of Ireland Cardiac and Stroke Foundation, Galway, Ireland
| | - Molly Byrne
- Health Behaviour Change Research Group, University of Galway, Galway, County Galway, Ireland
| | - Andrew William Murphy
- Health Research Board Primary Care Clinical Trials Network Ireland, University of Galway, Galway, County Galway, Ireland
| | - Caitlin Marie Reardon
- Veteran Affairs (VA) Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
| | - John William McEvoy
- School of Medicine, University of Galway, Galway, County Galway, Ireland
- National Institute for Prevention and Cardiovascular Health, Galway, Ireland
| | - Oonagh Meade
- School of Psychology, University of Galway, Galway, County Galway, Ireland
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Chen EW, Varghese MS, Wu WC. The Potential of Broadband Internet Availability in Improving Access to Cardiac Rehabilitation. J Cardiopulm Rehabil Prev 2024; 44:227-228. [PMID: 38959340 DOI: 10.1097/hcr.0000000000000895] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 07/05/2024]
Affiliation(s)
- Edward W Chen
- Author Affiliations: Department of Internal Medicine, Yale School of Medicine, (Dr Chen); Department of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut (Dr Varghese); Department of Cardiology, Veterans Affair Connecticut Healthcare System, West Haven, Connecticut (Dr Varghese); and Division of Cardiology, Department of Medicine, The Providence Veterans Affairs Medical Center, Lifespan Hospitals, and the Warren Alpert Medical School at Brown University, Providence, Rhode Island (Dr Wu)
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48
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Del Furia MJ, Arienti C, Cattadori G, Di Marco S, Kiekens C. Overview of Cochrane Systematic Reviews on Interventions for Rehabilitation in People with Ischemic Heart Disease: A Mapping Synthesis. J Clin Med 2024; 13:3662. [PMID: 38999228 PMCID: PMC11242865 DOI: 10.3390/jcm13133662] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/13/2024] [Revised: 06/06/2024] [Accepted: 06/14/2024] [Indexed: 07/14/2024] Open
Abstract
Objectives: This overview of Cochrane Systematic Reviews (CSRs) reports on current evidence and its certainty of the effectiveness of interventions for the rehabilitation of people with ischemic heart disease (IHD), included in the World Health Organization Rehabilitation Programme Package of Interventions for Rehabilitation. Methods: We included all the CSRs relevant to people with IHD. We used a mapping synthesis to group outcomes and comparisons of included CSRs, indicating the effectiveness of interventions for rehabilitation and the certainty of evidence. Results: The evidence map included a total of 13 CSRs. The effect of the interventions varied across comparisons, and the certainty of evidence was inconsistent, ranging from high to very low. We found the best evidence for exercise-based cardiac rehabilitation in the reduction of fatal and non-fatal myocardial infarction and all-cause hospital admission up to 12 months follow-up. Also, combined interventions (work-directed interventions, physical conditioning interventions, and psychological interventions) reduce the days needed for returning to work. Conclusions: The current effect and certainty of evidence for several comparisons investigated support the role of exercise-based cardiac rehabilitation in the management of people with IHD, specifically reducing the risk of fatal and non-fatal myocardial infarction and hospitalisation. However, our findings highlight the lack of high-certainty evidence about hard endpoints, particularly total mortality. Future research should prioritise these primary endpoints to enhance the credibility of cardiac rehabilitation.
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Affiliation(s)
- Matteo Johann Del Furia
- Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy;
- Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy
- IRCCS Istituto Ortopedico Galeazzi, 20157 Milan, Italy;
| | - Chiara Arienti
- Clinical Epidemiology and Research Center, Department of Biomedical Sciences, Humanitas University, Piave Emanuele, 20090 Milan, Italy;
| | - Gaia Cattadori
- Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy
- IRCCS MultiMedica, 20138 Milan, Italy;
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Keteyian SJ, Grimshaw C, Ehrman JK, Kerrigan DJ, Abdul-Nour K, Lanfear DE, Brawner CA. The iATTEND Trial: A Trial Comparing Hybrid Versus Standard Cardiac Rehabilitation. Am J Cardiol 2024; 221:94-101. [PMID: 38670326 PMCID: PMC11144075 DOI: 10.1016/j.amjcard.2024.04.034] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/16/2024] [Revised: 03/22/2024] [Accepted: 04/19/2024] [Indexed: 04/28/2024]
Abstract
The improving ATTENDance (iATTEND) to cardiac rehabilitation (CR) trial tested the hypotheses that hybrid CR (HYCR) (combination of virtual and in-facility CR sessions) would result in greater attendance compared with traditional, facility-based only CR (FBCR) and yield equivalent improvements in exercise capacity and health status. Patients were randomized to HYCR (n = 142) or FBCR (n = 140), stratified by gender and race. Attendance was assessed as number of CR sessions completed within 6 months (primary end point) and the percentage of patients completing 36 CR sessions. Other end points (tested for equivalency) included exercise capacity and self-reported health status. HYCR patients completed 1 to 12 sessions in-facility, with the balance completed virtually using synchronized, 2-way audiovisual technology. Neither total number of CR sessions completed within 6 months (29 ± 12 vs 28 ± 12 visits, adjusted p = 0.94) nor percentage of patients completing 36 sessions (59 ± 4% vs 51 ± 4%, adjusted p = 0.32) were significantly different between HYCR and FBCR, respectively. The between-group changes for exercise capacity (peak oxygen uptake, 6-minute walk distance) and health status were equivalent. Regarding safety, no sessions required physician involvement, there was 1 major adverse event after a virtual session, and no falls required medical attention. In conclusion, although we rejected our primary hypothesis that attendance would be greater with HYCR versus FBCR, we showed that FBCR and HYCR resulted in similar patient attendance patterns and equivalent improvements in exercise capacity and health status. HYCR which incorporates virtually supervised exercise should be considered an acceptable alternative to FBCR. NCT Identifier: 03646760; The Improving ATTENDance to Cardiac Rehabilitation Trial - Full-Text View - ClinicalTrials. gov; https://classic.clinicaltrials.gov/ct2/show/NCT03646760.
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Affiliation(s)
- Steven J Keteyian
- Division of Cardiovascular Medicine, Department of Medicine, Henry Ford Health Detroit, Michigan.
| | - Crystal Grimshaw
- Division of Cardiovascular Medicine, Department of Medicine, Henry Ford Health Detroit, Michigan
| | - Jonathan K Ehrman
- Division of Cardiovascular Medicine, Department of Medicine, Henry Ford Health Detroit, Michigan
| | - Dennis J Kerrigan
- Division of Cardiovascular Medicine, Department of Medicine, Henry Ford Health Detroit, Michigan
| | - Khaled Abdul-Nour
- Division of Cardiovascular Medicine, Department of Medicine, Henry Ford Health Detroit, Michigan
| | - David E Lanfear
- Division of Cardiovascular Medicine, Department of Medicine, Henry Ford Health Detroit, Michigan
| | - Clinton A Brawner
- Division of Cardiovascular Medicine, Department of Medicine, Henry Ford Health Detroit, Michigan
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50
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Spatola CAM, Rapelli G, Giusti EM, Cattivelli R, Goodwin CL, Pietrabissa G, Malfatto G, Facchini M, Cappella EAM, Varallo G, Martino G, Castelnuovo G. Effects of a brief intervention based on Acceptance and Commitment Therapy versus usual care for cardiac rehabilitation patients with coronary heart disease (ACTonHEART): a randomised controlled trial. BMJ Open 2024; 14:e084070. [PMID: 38866567 PMCID: PMC11177674 DOI: 10.1136/bmjopen-2024-084070] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/09/2024] [Accepted: 05/20/2024] [Indexed: 06/14/2024] Open
Abstract
OBJECTIVES The main objective of the study is to investigate the short-term efficacy of Acceptance and Commitment Therapy (ACT) on the simultaneous modification of biological indicators of risk and psychological well-being in patients with coronary heart disease attending cardiac rehabilitation (CR). DESIGN This was a two-arm randomised controlled trial comparing a brief, manualised, ACT-based intervention with usual care (UC). SETTING The study was conducted in an outpatient CR unit in Italy. Data collection took place from January 2016 to July 2017. PARTICIPANTS Ninety-two patients were enrolled and randomised, following an unbalanced randomisation ratio of 2:1 to the ACT group (n=59) and the control group (n=33). Eighty-five patients completed the ACT (n=54) and the UC (n=31) interventions and were analysed. INTERVENTIONS The control group received UC, a 6 weeks multidisciplinary outpatient CR programme, encompassing exercise training, educational counselling and medical examinations. The experimental group, in addition to UC, participated in the Acceptance and Commitment Therapy on HEART disease (ACTonHEART) intervention encompassing three group sessions based on ACT. OUTCOMES The primary outcomes were Low Density Lipoproteins (LDL)cholesterol, resting systolic blood pressure, body mass index (BMI) and psychological well-being measured by the Psychological General Well-Being Index (PGWBI). Outcome measures were assessed at baseline and at the end of CR. RESULTS Based on linear mixed models, no significant group × time interaction was observed for either the primary outcomes (β, 95% CI: PGWBI =-1.13, -6.40 to -4.14; LDL cholesterol =-2.13, -11.02 to -6.76; systolic blood pressure =-0.50, -10.76 to -9.76; diastolic blood pressure =-2.73, -10.12 to -4.65; BMI =-0.16, -1.83 to -1.51, all p values >0.05) or the secondary outcomes (all p values >0.05). A significant time effect was found for the PGWBI total (beta=4.72; p=0.03). CONCLUSIONS Although analyses revealed null findings, the results can inform the design of future ACT-based CR interventions and can help researchers to strike a balance between the idealised implementation of an ACT intervention and the structural limitations of existing CR programmes. TRIAL REGISTRATION NUMBER NCT01909102.
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Affiliation(s)
- Chiara A M Spatola
- Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
| | - Giada Rapelli
- Department of Psychology Renzo Canestrari, Alma Mater Studiorum University of Bologna, Bologna, Italy
| | | | - Roberto Cattivelli
- Department of Psychology Renzo Canestrari, Alma Mater Studiorum University of Bologna, Bologna, Italy
| | - Christina L Goodwin
- Cooper University Health Care, Camden, New Jersey, USA
- Cooper University Medical School of Rowan University, Camden, New Jersey, USA
| | - Giada Pietrabissa
- IRCCS Istituto Auxologico Italiano, Clinical Psychology Research Laboratory, Milan, Italy
| | - Gabriella Malfatto
- Istituto Auxologico Italiano IRCCS, Dipartimento di Scienze Cardiovascolari, Neurologiche, Metaboliche, Ospedale San Luca, Milano, Italy
| | - Mario Facchini
- Istituto Auxologico Italiano IRCCS, Dipartimento di Scienze Cardiovascolari, Neurologiche, Metaboliche, Ospedale San Luca, Milano, Italy
| | | | - Giorgia Varallo
- Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
| | - Gabriella Martino
- Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
| | - Gianluca Castelnuovo
- IRCCS Istituto Auxologico Italiano, Clinical Psychology Research Laboratory, Milan, Italy
- Catholic University of the Sacred Heart, Milano, Italy
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