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Copyright ©The Author(s) 2015.
World J Nephrol. May 6, 2015; 4(2): 287-294
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.287
Table 1 Recommendations for antibiotics choice in peritoneal dialysis-related peritonitis
Monitoring the etiologies and antimicrobial resistance profile
YesNo
Initial (empirical) protocolStart intraperitoneal antibiotics to cover gram-positive and gram roads, according to local microbiologic profileStart a glycopeptide (gram-positive coverage) plus ceftazidime (gram-negative coverage), both by intraperitoneal route1
After results of culture and in vitro susceptibility testsCulture positive: adjust the treatment according to bacterial susceptibility. If Pseudomonas spp on culture, add a second anti-pseudomonas drug acting in different ways that organism is sensitive to2Culture positive: adjust the treatment according to bacterial susceptibility. If Pseudomonas spp on culture, add a second anti-pseudomonas drug acting in different ways that organism is sensitive to2
Culture negative: continue initial antibioticsCulture negative: Continue initial antibiotics
Therapy durationPseudomonas spp, Enterococcus/Streptococcus spp = 21 d
Non-pseudomonas single gram-negative = 14-21 d
Culture negative, coagulase negative staphylococcus, other gram-positive roads = 14 d