Copyright ©The Author(s) 2015.
World J Nephrol. May 6, 2015; 4(2): 245-253
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.245
Table 1 Treatment options for hypogonadism in men desiring to preserve their fertility
Name of medicationDosing and administrationSide effectsAnticipated results
ClomipheneOral: 25 mg every other day with max of 50 mg dailyGynecomastia, weight gain, hypertension, cataracts, and acneRecovery of spermatogenetic function, increases in testosterone levels
hCGIntramuscular injection; 125-500 IU every other dayHeadache, restlessness, tiredness, swelling of the ankles/feet, mental/mood changes, pain/swelling of the breastRecovery of spermatogenetic function, increases in testosterone levels
hMGIntramuscular injection; 75 IU three times a weekGynecomastia, dizziness, fainting, headache, loss of appetite, irregular heartbeatRecovery of spermatogenetic function
AnastrozoleOral; either 0.5 or 1 mgBlood pressure increase, anorexia, malaise, rash, peripheral edema, aches glossitis, paresthesias vomiting/nauseaImprovements in T/E2 ratio, increases in sperm concentration