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Copyright ©2014 Baishideng Publishing Group Inc.
World J Nephrol. Nov 6, 2014; 3(4): 295-301
Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.295
Table 1 Summary of angiotensin II effects on tubular transport
Nephron segmentPotential targetsEffectsRef.
PTNHE3, NBCe1biphasic in rats, mice, rabbits[19,27-32]
JHCO3monophasic stimulation in humans[84]
TALNKA, NKCC2, Cl channelstimulation[40-43]
NADPH oxidase
DCTNCCstimulation[47,49]
WNK4?
CNT/CDENaCstimulation[55,59-61]
Table 2 Summary of nitric oxide effects on tubular transport
Nephron segmentPotential targetsEffectsRef.
PTNHE3, NBCe1inhibition in rats, mice, rabbits[65-68,84]
JHCO3biphasic in rats?[64]
monophasic stimulation in humans[84]
TALNKA, NKCC2inhibition[69-72]
JCl, JHCO3
CNT/CDENaCinhibition[81,83]