Copyright ©The Author(s) 2022.
World J Virol. Jan 25, 2022; 11(1): 40-56
Published online Jan 25, 2022. doi: 10.5501/wjv.v11.i1.40
Table 1 Comparison of available animal models for SARS-CoV-2 infection
Animal model
Upper respiratory tract
Lower respiratory tract
Feces/Fecal swab
Contact transmission
Airborne transmission
Weight loss
1Cat (6 to 9 mo)Infectious virusNilPresentNot reported33%Not reported[72]
2ChickenNilNilNot reportedNilNot reportedNot reported[72]
3DogNilNilPresentNilNot reportedNot reported[72]
4DuckNilNilNot reportedNilNot reportedNot reported[72]
5FerretInfectious virusInfectious virusPresent100%30%Not reported[72,73]
6hACE2 mouseNot reportedInfectious titerInfectious titerNot reportedNot reportedPresent[57]
7HamsterInfectious titerInfectious titerInfectious titer100%Not reportedPresent[59]
8KittenInfectious titerInfectious titerNot reportedNot reported33%Not reported[72]
9MacaquePresentPresentNot reportedNot reportedNot reportedNil[80]
10PigNilNilNot reportedNilNot reportedNot reported[72]